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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

2,351–2,400 of 18,558 reactions from Rhea

dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
Direction not assertedBalancedRhea 19873
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate) + ADP + H(+)
Left to rightBalance undeterminableRhea 19877
L-lysyl-[protein] + GTP = N(epsilon)-GMP-L-lysyl-[protein] + diphosphate + H(+)
Direction not assertedBalance undeterminableRhea 19881
(S)-reticuline + O2 = (S)-scoulerine + H2O2 + H(+)
Direction not assertedBalancedRhea 19885
alpha-D-glucose 1-phosphate + UTP + H(+) = UDP-alpha-D-glucose + diphosphate
Left to rightBalancedRhea 19889
4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + ATP = 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + ADP
Direction not assertedBalancedRhea 19893

2 L-arginine + 3 NADPH + 4 O2 + H(+) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H2O

Left to rightBalancedRhea 19897

L-tryptophan + O2 = alpha,beta-didehydrotryptophan + H2O2

Direction not assertedBalancedRhea 19901

spermidine + NAD(+) = dehydrospermidine + NADH + H(+)

Direction not assertedBalancedRhea 19905

(S)-lactate + 2 Fe(III)-[cytochrome c] = 2 Fe(II)-[cytochrome c] + pyruvate + 2 H(+)

Direction not assertedBalance undeterminableRhea 19909

a (3R)-hydroxyacyl-[ACP] + NAD(+) = a 3-oxoacyl-[ACP] + NADH + H(+)

Direction not assertedBalance undeterminableRhea 19913

D-ribitol 5-phosphate + NADP(+) = D-ribulose 5-phosphate + NADPH + H(+)

Direction not assertedBalancedRhea 19921

D-ribitol 5-phosphate + NAD(+) = D-ribulose 5-phosphate + NADH + H(+)

Direction not assertedBalancedRhea 19925

[(1->4)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-beta-D-glucosyl](n+1) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 19929

alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate

Left to rightBalancedRhea 19933

glycine + S-adenosyl-L-methionine = sarcosine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 19937

norcoclaurine + S-adenosyl-L-methionine = coclaurine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 19941

N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 19945

(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate = 7,8-dihydropteroate + diphosphate

Direction not assertedBalancedRhea 19949

a 2-oxocarboxylate + L-alanine = an L-alpha-amino acid + pyruvate

Direction not assertedBalance undeterminableRhea 19953

2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H(+)

Direction not assertedBalancedRhea 19957

a 2'-deoxyribonucleoside + a ribonucleoside 5'-phosphate = a ribonucleoside + a 2'-deoxyribonucleoside 5'-phosphate

Direction not assertedBalance undeterminableRhea 19961

S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H(+)

Direction not assertedBalancedRhea 19965

hydroxylamine + O2 = nitrite + H2O + H(+)

Direction not assertedBalancedRhea 19969

S-adenosyl 3-(methylsulfanyl)propylamine + spermidine = spermine + S-methyl-5'-thioadenosine + H(+)

Left to rightBalancedRhea 19973

L-tyrosine methyl ester + 3'-phosphoadenylyl sulfate = L-tyrosine methyl ester 4-sulfate + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 19977

S-(hydroxymethyl)glutathione + NADP(+) = S-formylglutathione + NADPH + H(+)

Direction not assertedBalancedRhea 19981

S-(hydroxymethyl)glutathione + NAD(+) = S-formylglutathione + NADH + H(+)

Direction not assertedBalancedRhea 19985

5-(methylsulfanyl)-alpha-D-ribose 1-phosphate = 5-(methylsulfanyl)-D-ribulose 1-phosphate

Direction not assertedBalancedRhea 19989

[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol

Direction not assertedBalance undeterminableRhea 19993

phosphoenolpyruvate + H2O = pyruvate + phosphate

Direction not assertedBalancedRhea 19997

glycolaldehyde + NAD(+) + H2O = glycolate + NADH + 2 H(+)

Direction not assertedBalancedRhea 20001

an alpha-D-glucuronoside + H2O = D-glucuronate + an alcohol

Direction not assertedBalance undeterminableRhea 20005

2-hydroxy-2-methylpropanenitrile + UDP-alpha-D-glucose = linamarin + UDP + H(+)

Direction not assertedBalancedRhea 20009

carbamoyl phosphate + L-aspartate = N-carbamoyl-L-aspartate + phosphate + H(+)

Direction not assertedBalancedRhea 20013

5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H2 = 5,10-methylenetetrahydromethanopterin + H(+)

Direction not assertedBalancedRhea 20017

deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2

Direction not assertedBalancedRhea 20021

gibberellin A3 + UDP-alpha-D-glucose = gibberellin A3 O-beta-D-glucoside + UDP + H(+)

Direction not assertedBalancedRhea 20025

10-deoxysarpagine + NADP(+) = vellosimine + NADPH + H(+)

Direction not assertedBalancedRhea 20029

isopenicillin N = penicillin N

Direction not assertedBalancedRhea 20033

D-sorbitol 6-phosphate + NADP(+) = aldehydo-D-glucose 6-phosphate + NADPH + H(+)

Direction not assertedBalancedRhea 20037

3-oxopropanoate + NADP(+) + H2O = malonate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 20041

3-oxopropanoate + NAD(+) + H2O = malonate + NADH + 2 H(+)

Direction not assertedBalancedRhea 20045

1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide

Direction not assertedBalancedRhea 20049

ribitol + NAD(+) = D-ribulose + NADH + H(+)

Direction not assertedBalancedRhea 20053

N-carbamoylsarcosine + H2O + 2 H(+) = sarcosine + NH4(+) + CO2

Direction not assertedBalancedRhea 20057

2'-deoxycytidine + a ribonucleoside 5'-triphosphate = dCMP + a ribonucleoside 5'-diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 20061

2'-deoxymugineate + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineate + succinate + CO2 + H(+)

Direction not assertedBalancedRhea 20065

(Z)-phenylacetaldehyde oxime = phenylacetonitrile + H2O

Direction not assertedBalancedRhea 20069

D-allo-threonine = acetaldehyde + glycine

Direction not assertedBalancedRhea 20073

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