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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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AssessmentsRegulatory determinations, transcribed
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

23,601–23,650 of 31,435, by identifier

(3S)-3-hydroxypentanoyl-CoA + H2O = (3S)-3-hydroxypentanoate + CoA + H(+)
Direction not assertedBalancedRhea 55096
3-oxopentanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxypentanoyl-[ACP] + NADP(+)
Direction not assertedBalance undeterminableRhea 55100
3-oxoheptanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxyheptanoyl-[ACP] + NADP(+)
Direction not assertedBalance undeterminableRhea 55104
3-oxononanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxynonanoyl-[ACP] + NADP(+)
Direction not assertedBalance undeterminableRhea 55108
4-methyl-3-oxopentanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxy-4-methylpentanoyl-[ACP] + NADP(+)
Direction not assertedBalance undeterminableRhea 55112
5-methyl-3-oxohexanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxy-5-methylhexanoyl-[ACP] + NADP(+)
Direction not assertedBalance undeterminableRhea 55116

4-methyl-3-oxohexanoyl-[ACP] + NADPH + H(+) = (3R)-hydroxy-4-methylhexanoyl-[ACP] + NADP(+)

Direction not assertedBalance undeterminableRhea 55120

(2E)-5-methylhexenoyl-[ACP] + NADH + H(+) = 5-methylhexanoyl-[ACP] + NAD(+)

Direction not assertedBalance undeterminableRhea 55124

(3R)-hydroxy-5-methylhexanoyl-[ACP] = (2E)-5-methylhexenoyl-[ACP] + H2O

Direction not assertedBalance undeterminableRhea 55128

holo-[D-alanyl-carrier protein] + D-alanine + ATP = D-alanyl-[D-alanyl-carrier protein] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 55132

D-alanine + ATP + H(+) = D-alanyl-5'-AMP + diphosphate

Direction not assertedBalancedRhea 55136

D-alanyl-5'-AMP + holo-[D-alanyl-carrier protein] = D-alanyl-[D-alanyl-carrier protein] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 55140

[(3S,4R)-4-(6-methylheptanoyl)-5-oxooxolan-3-yl]methyl phosphate + NADP(+) = [4-(6-methylheptanoyl)-5-oxo-2H-furan-3-yl]methyl phosphate + NADPH + H(+)

Direction not assertedBalancedRhea 55144

a [(3S,4R)-4-alkanoyl-5-oxooxolan-3-yl]methyl phosphate + NADP(+) = a (4-alkanoyl-5-oxo-2,5-dihydrofuran-3-yl)methyl phosphate + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 55148

L-prolyl-[peptidyl-carrier protein] + 2 oxidized [electron-transfer flavoprotein] + H(+) = (1H-pyrrole-2-carbonyl)-[peptidyl-carrier protein] + 2 reduced [electron-transfer flavoprotein]

Direction not assertedBalance undeterminableRhea 55152

a quinone + hydrogen sulfide + glutathione + H(+) = S-sulfanylglutathione + a quinol

Left to rightBalance undeterminableRhea 55156

coenzyme B + coenzyme M + 2 oxidized [2Fe-2S]-[ferredoxin] = coenzyme M-coenzyme B heterodisulfide + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)

Direction not assertedBalance undeterminableRhea 55160

a jasmonyl-L-isoleucinate + NADPH + O2 + H(+) = L-isoleucine-12-hydroxyjasmonate + NADP(+) + H2O

Direction not assertedBalancedRhea 55164

[TtuB sulfur-carrier protein]-C-terminal Gly-Gly + ATP + H(+) = [TtuB sulfur-carrier protein]-C-terminal Gly-Gly-AMP + diphosphate

Direction not assertedBalance undeterminableRhea 55168

hexanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxyhexanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 55172

butanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxybutanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 55176

3-methylnonanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxy-3-methylnonanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 55180

3-methylundecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxy-3-methylundecanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 55184

5-methyluridine(54) in tRNA + hydrogen sulfide + ATP = 5-methyl-2-thiouridine(54) in tRNA + AMP + diphosphate

Direction not assertedBalancedRhea 55188

3-methyldodecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxy-3-methyldodecanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 55192

2-hydroxyoctadecanoyl-CoA = heptadecanal + formyl-CoA

Left to rightBalancedRhea 55196

5-amino-6-(D-ribitylamino)uracil + L-tyrosine + S-adenosyl-L-methionine = 5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + 2-iminoacetate + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalancedRhea 55200

5-amino-5-(4-hydroxybenzyl)-6-(D-ribitylimino)-5,6-dihydrouracil + S-adenosyl-L-methionine = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 5'-deoxyadenosine + L-methionine + NH4(+) + H(+)

Direction not assertedBalancedRhea 55204

(4R)-hydroxysphinganine 1-phosphate = (2R)-hydroxyhexadecanal + phosphoethanolamine

Direction not assertedBalancedRhea 55208

(2R)-hydroxyhexadecanoyl-CoA = pentadecanal + formyl-CoA

Left to rightBalancedRhea 55212

(2E,6E,10E)-geranylgeranyl diphosphate = rhizathalene A + diphosphate

Direction not assertedBalancedRhea 55216

4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) = 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + 6 Fe(III)-[cytochrome b5] + 4 H2O

Left to rightBalance undeterminableRhea 55220

4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 55224

4alpha-hydroxymethyl-4beta-methyl-5alpha-cholest-7-en-3beta-ol + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 55228

3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + 2 Fe(II)-[cytochrome b5] + O2 + H(+) = 2 Fe(III)-[cytochrome b561] + 4alpha-carboxy-4beta-methyl-5alpha-cholest-7-ene-3beta-ol + H2O

Direction not assertedBalance undeterminableRhea 55232

1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(N-hexadecanoyl)-serine + H2O = 1-octadecanoyl-2-hydroxy-sn-glycero-3-phospho-(N-hexadecanoyl)-serine + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 55236

1-O-(1Z-octadecenoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + H2O = 1-O-(1Z-octadecenyl)-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + (9Z)-octadecenoate + H(+)

Left to rightBalancedRhea 55240

4,4-dimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 6 Fe(II)-[cytochrome b5] + 3 O2 + 5 H(+) = 4beta-methylzymosterol-4alpha-carboxylate + 6 Fe(III)-[cytochrome b5] + 4 H2O

Left to rightBalance undeterminableRhea 55244

1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = N-octadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 55248

1-hexadecanoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = 2-octadecanoyl-sn-glycero-3-phosphocholine + N-hexadecanoyl-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+)

Left to rightBalancedRhea 55252

1,2-di-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 55256

2 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine = N,1,2-tri-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + H(+)

Left to rightBalancedRhea 55260

N-(30-hydroxytriacontanoyl)-sphing-4-enine + 1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol = N-[30-(9Z,12Z-octadecadienoyloxy)-triacontanoyl]-sphing-4-enine + di-(9Z,12Z)-octadecadienoylglycerol

Left to rightBalancedRhea 55264

(2R)-2-O-(alpha-D-glucopyranosyl)-glycerate + phosphate = (R)-glycerate + alpha-D-glucose 1-phosphate

Direction not assertedBalancedRhea 55268

11-cis-retinol + tetradecanoyl-CoA = 11-cis-retinyl tetradecanoate + CoA

Left to rightBalancedRhea 55272

9-cis-retinol + tetradecanoyl-CoA = 9-cis-retinyl tetradecanoate + CoA

Left to rightBalancedRhea 55276

13-cis-retinol + tetradecanoyl-CoA = 13-cis-retinyl tetradecanoate + CoA

Left to rightBalancedRhea 55280

all-trans-retinol + tetradecanoyl-CoA = all-trans-retinyl tetradecanoate + CoA

Left to rightBalancedRhea 55284

tetradecan-1-ol + tetradecanoyl-CoA = tetradecyl tetradecanoate + CoA

Left to rightBalancedRhea 55288

pseudouridine(54) in tRNA + S-adenosyl-L-methionine = N(1)-methylpseudouridine(54) in tRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 55292

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