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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

23,201–23,250 of 31,435, by identifier

1-hexadecanoyl-2-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + cholesterol = (6Z,9Z,12Z-octadecatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Left to rightBalancedRhea 53476
3beta-hydroxy-5alpha-androstan-17-one + NADPH + H(+) = 5alpha-androstane-3beta,17beta-diol + NADP(+)
Left to rightBalancedRhea 53480
androst-4-ene-3,11,17-trione + NADPH + H(+) = 17beta-hydroxyandrost-4-ene-3,11-dione + NADP(+)
Left to rightBalancedRhea 53484
11beta-hydroxyandrost-4-ene-3,17-dione + NADPH + H(+) = 11beta,17beta-dihydroxyandrost-4-ene-3-one + NADP(+)
Left to rightBalancedRhea 53488
5-methyl-5,6,7,8-tetrahydromethanopterin + coenzyme M + 2 Na(+)(in) = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M + 2 Na(+)(out)
Direction not assertedBalancedTransportRhea 53492
1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O = hexanoate + a 2-acyl-sn-glycero-3-phosphocholine + H(+)
Left to right

Balance undeterminable

Rhea 53496

1-hexanoyl-2-acyl-sn-glycero-3-phosphocholine + H2O = 1-hexanoyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 53500

5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + AH2 + S-adenosyl-L-methionine = 5-hydroxybenzimidazole + 5'-deoxyadenosine + formate + L-methionine + A + NH4(+) + phosphate + 2 H(+)

Direction not assertedBalancedRhea 53504

(13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + glutathione = (13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate

Left to rightBalancedRhea 53508

(13R)-S-glutathionyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O = (13R)-S-cysteinylglycyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + L-glutamate

Left to rightBalancedRhea 53512

1-hexadecanoyl-2-(11Z,14Z,17Z-eicosatrienoyl)-sn-glycero-3-phosphocholine + cholesterol = (11Z,14Z,17Z-eicosatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine

Left to rightBalancedRhea 53516

1-hexadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + cholesterol = (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + 1-hexadecanoyl-sn-glycero-3-phosphocholine

Left to rightBalancedRhea 53520

1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine = 1,2-diheptadecanoyl-sn-glycero-3-phospho-N-hexadecanoyl-ethanolamine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 53524

1,2-diheptadecanoyl-sn-glycero-3-phosphoethanolamine + 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine = 1,2-diheptadecanoyl-sn-glycero-3-phospho-N-(9Z-octadecenoyl)-ethanolamine + 2-hexadecanoyl-sn-glycero-3-phosphocholine + H(+)

Left to rightBalancedRhea 53528

(14S)-hydroperoxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate = (13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O

Left to rightBalancedRhea 53532

(13S,14S)-epoxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O = (13R,14S)-dihydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate

Direction not assertedBalancedRhea 53536

(13R)-S-cysteinylglycyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + H2O = (13R)-S-cysteinyl-(14S)-hydroxy-(4Z,7Z,9E,11E,16Z,19Z)-docosahexaenoate + glycine

Direction not assertedBalancedRhea 53540

chlorophyll a + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O = 7(1)-hydroxychlorophyll a + 2 reduced [2Fe-2S]-[ferredoxin] + 2 H(+)

Direction not assertedBalance undeterminableRhea 53544

prostaglandin J2 = Delta(12)-prostaglandin J2

Direction not assertedBalancedRhea 53548

(9S,10R)-epoxy-octadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-(9S,10R)-epoxy-octadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53552

(9R,10S)-epoxy-octadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-(9R,10S)-epoxy-octadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53556

9,10-epoxyoctadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-9,10-epoxy-octadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53560

9,10-epoxy-(12Z)-octadecenoate + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-9,10-epoxy-(12Z)-octadecenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53564

12,13-epoxy-(9Z)-octadecenoate + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-12,13-epoxy-(9Z)-octadecenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53568

8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy-8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53572

11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy-11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53576

14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy-14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 53580

resolvin D2 + NAD(+) = 7-oxoresolvin D2 + NADH + H(+)

Left to rightBalancedRhea 53584

resolvin D2 + NAD(+) = 16-oxoresolvin D2 + NADH + H(+)

Left to rightBalancedRhea 53588

1-tetradecanoyl-sn-glycerol 3-phosphate + H2O = 1-tetradecanoyl-sn-glycerol + phosphate

Left to rightBalancedRhea 53592

1-octadecanoyl-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycerol + phosphate

Left to rightBalancedRhea 53596

1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 53600

1-hexadecanoyl-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-sn-glycerol + phosphate

Left to rightBalancedRhea 53604

4-hydroxyestrone + O2 = (2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + H(+)

Direction not assertedBalancedRhea 53608

D-ribulose 5-phosphate + CTP + H(+) = CDP-D-ribulose + diphosphate

Direction not assertedBalancedRhea 53612

(2E,6E)-farnesyl diphosphate + H2O = (+)-isoafricanol + diphosphate

Direction not assertedBalancedRhea 53616

(2E,6E,10E)-geranylgeranyl diphosphate = (-)-spiroviolene + diphosphate

Direction not assertedBalancedRhea 53620

(2E,6E,10E)-geranylgeranyl diphosphate = tsukubadiene + diphosphate

Direction not assertedBalancedRhea 53624

(2E,6E)-farnesyl diphosphate = (2S,3R,6S,9S)-(-)-protoillud-7-ene + diphosphate

Direction not assertedBalancedRhea 53628

(2E,6E)-farnesyl diphosphate = (3S)-(+)-asterisca-2(9),6-diene + diphosphate

Direction not assertedBalancedRhea 53632

a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-acetyl-sn-glycero-3-phosphocholine + a 1-O-alkyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 53636

(2E,6E)-farnesyl diphosphate = (-)-alpha-amorphene + diphosphate

Direction not assertedBalancedRhea 53640

(2E,6E)-farnesyl diphosphate + H2O = (+)-corvol ether B + diphosphate

Direction not assertedBalancedRhea 53644

(2E,6E)-farnesyl diphosphate + H2O = (+)-corvol ether A + diphosphate

Direction not assertedBalancedRhea 53648

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S,15S)-dihydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate

Left to rightBalancedRhea 53652

(5S,6R)-dihydroxy-(7E,9E,11Z,14Z)-eicosatetraenoate + O2 = (5S,6R)-dihydroxy-(15S)-hydroperoxy-(7E,9E,11Z,13E)-eicosatetraenoate

Left to rightBalancedRhea 53656

(5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S)-hydroxy-(15S)-hydroperoxy-(6E,8Z,11Z,13E)-eicosatetraenoate

Left to rightBalancedRhea 53660

(2Z,10Z)-3-hydroxy-5,17-dioxo-4,5-secoestra-2,10-diene-3-oate + NH4(+) = pyridinestrone carboxylate + 2 H2O + H(+)

Direction not assertedBalancedRhea 53664

(2E,6E)-farnesyl diphosphate = (1R,4R,5S)-(-)-guaia-6,10(14)-diene + diphosphate

Direction not assertedBalancedRhea 53668

2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + AH2 + O2 = 2-[(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoyl]-sn-glycero-3-phosphoethanolamine + A + H2O

Direction not assertedBalancedRhea 53672

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