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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

22,951–23,000 of 31,435, by identifier

16alpha,17beta-estriol + UDP-alpha-D-glucuronate = 16alpha,17beta-estriol 3-O-(beta-D-glucuronate) + UDP + H(+)
Left to rightBalancedRhea 52468
16alpha,17beta-estriol + UDP-alpha-D-glucuronate = 16alpha,17beta-estriol 16-O-(beta-D-glucuronate) + UDP + H(+)
Left to rightBalancedRhea 52472
estrone + UDP-alpha-D-glucuronate = estrone 3-O-(beta-D-glucuronate) + UDP + H(+)
Left to rightBalancedRhea 52476
16-methoxytabersonine + reduced [NADPH--hemoprotein reductase] + O2 = (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 52480
(3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + A = (3R)-1,2-didehydro-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + AH2
Direction not assertedBalancedRhea 52484
prostaglandin E2 + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy prostaglandin E2 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not asserted

?

Balance undeterminable

Rhea 52488

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52492

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52496

(9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + O2 = (13R)-hydroxy-(9Z,11E)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52500

(9Z,12Z)-octadecadienoate + reduced [NADPH--hemoprotein reductase] + O2 = (9R)-hydroxy-(10E,12Z)-octadecadienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52504

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 13(S)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 52508

trans-4-hydroxy-L-proline + a quinone = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + a quinol + H(+)

Direction not assertedBalance undeterminableRhea 52512

ubiquinone-10 + trans-4-hydroxy-L-proline = (3R,5S)-1-pyrroline-3-hydroxy-5-carboxylate + ubiquinol-10 + H(+)

Direction not assertedBalancedRhea 52516

prostaglandin E1 + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy prostaglandin E1 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 52520

prostaglandin A1 + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy prostaglandin A1 + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 52524

L-asparagine + 2-oxoglutarate = 2-oxosuccinamate + L-glutamate

Direction not assertedBalancedRhea 52528

adenosine + GTP = GDP + AMP + H(+)

Direction not assertedBalancedRhea 52532

dGTP + adenosine = dGDP + AMP + H(+)

Direction not assertedBalancedRhea 52536

cytidine + phosphate = cytosine + alpha-D-ribose 1-phosphate

Direction not assertedBalancedRhea 52540

D-erythronate + NAD(+) = 2-dehydro-D-erythronate + NADH + H(+)

Direction not assertedBalancedRhea 52544

L-threonate + NAD(+) = 2-dehydro-L-erythronate + NADH + H(+)

Direction not assertedBalancedRhea 52548

3-dehydro-L-erythronate + ATP = 3-dehydro-4-O-phospho-L-erythronate + ADP + H(+)

Direction not assertedBalancedRhea 52552

3-dehydro-D-erythronate + ATP = 3-dehydro-4-O-phospho-D-erythronate + ADP + H(+)

Direction not assertedBalancedRhea 52556

2-dehydro-D-erythronate = 3-dehydro-D-erythronate

Direction not assertedBalancedRhea 52560

2-dehydro-L-erythronate = 3-dehydro-L-erythronate

Direction not assertedBalancedRhea 52564

epitestosterone + UDP-alpha-D-glucuronate = epitestosterone 17-O-(beta-D-glucuronate) + UDP + H(+)

Left to rightBalancedRhea 52568

butanoyl-CoA + NAD(+) = (2E)-butenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 52572

hexanoyl-CoA + NAD(+) = (2E)-hexenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 52576

Pb(2+)(in) + ATP + H2O = Pb(2+)(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 52580

chenodeoxycholoyl-CoA + NAD(+) = 7alpha-hydroxy-3-oxochol-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 52584

choloyl-CoA + NAD(+) = 7alpha,12alpha-dihydroxy-3-oxochol-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 52588

deoxycholoyl-CoA + NAD(+) = 12alpha-hydroxy-3-oxocholan-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 52592

lithocholoyl-CoA + NAD(+) = 3-oxocholan-24-oyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 52596

propanoyl-CoA + L-methionine = N-propanoyl-L-methioninate + CoA + H(+)

Direction not assertedBalancedRhea 52600

3-O-(N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D-mannosyl)-L-seryl-[protein] + ATP = 3-O-(N-acetyl-beta-D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-6-O-phospho-alpha-D-mannosyl)-L-seryl-[protein] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 52604

2-hydroxybutanoate + NADP(+) = 2-oxobutanoate + NADPH + H(+)

Direction not assertedBalancedRhea 52608

3-(methylsulfanyl)propanoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = 3-(methylsulfanyl)acryloyl-CoA + reduced [electron-transfer flavoprotein]

Direction not assertedBalance undeterminableRhea 52612

3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-alpha-D-Man]-L-Thr-[protein] + ATP = 3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 52616

3-methylbutanoyl-CoA = 2,2-dimethylpropanoyl-CoA

Direction not assertedBalancedRhea 52620

[amino-group carrier protein]-C-terminal-L-glutamate + L-glutamate + ATP = [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 52624

an N-fatty-acyl-L-alpha-amino acid + H2O = an L-alpha-amino acid + a fatty acid

Direction not assertedBalance undeterminableRhea 52628

[amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate + ATP = [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate + ADP

Direction not assertedBalance undeterminableRhea 52632

a 5-methyl-2'-deoxycytidine in DNA + 2-oxoglutarate + O2 = a 5-hydroxymethyl-2'-deoxycytidine in DNA + succinate + CO2

Left to rightBalance undeterminableRhea 52636

(2R)-2-O-[alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl-(1->2)]-glycerate + octanoyl-CoA = (2R)-2-O-[6-O-octanoyl-alpha-D-glucopyranosyl-(1->6)-alpha-D-glucopyranosyl-(1->2)]-glycerate + CoA

Direction not assertedBalancedRhea 52640

D-xylono-1,4-lactone 5-phosphate + H2O = 5-phospho-D-xylonate + H(+)

Direction not assertedBalancedRhea 52644

L-arabino-1,4-lactone 5-phosphate + H2O = 5-phospho-L-arabinonate + H(+)

Direction not assertedBalancedRhea 52648

lanosterol + S-adenosyl-L-methionine = eburicol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 52652

a long-chain (3S)-3-hydroxy fatty acyl-CoA + NAD(+) = a long-chain 3-oxo-fatty acyl-CoA + NADH + H(+)

Left to rightBalance undeterminableRhea 52656

an L-alpha-amino acid + holo-[ACP] + ATP = an L-alpha-aminoacyl-[ACP] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 52660

a short-chain (3S)-3-hydroxyacyl-CoA = a short-chain (2E)-enoyl-CoA + H2O

Direction not assertedBalance undeterminableRhea 52664

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