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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

22,601–22,650 of 31,435, by identifier

5alpha-androst-1-ene-3,17-dione + A = androsta-1,4-diene-3,17-dione + AH2
Direction not assertedBalancedRhea 51060
lithocholate + 3'-phosphoadenylyl sulfate = lithocholate 3-sulfate + adenosine 3',5'-bisphosphate + H(+)
Left to rightBalancedRhea 51064
(2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol + pyruvate = (3S,5R,10R,12S,14S,15R,16R)-3,5,10,14,15-pentahydroxy-12,16-dimethylicosan-2-one + L-alanine
Direction not assertedBalancedRhea 51068
an aryl sulfate + a phenol = an aryl sulfate + a phenol
Direction not assertedBalance undeterminableRhea 51072
2-hydroxy-17beta-estradiol + 3'-phosphoadenylyl sulfate = 2-hydroxy-17beta-estradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)
Direction not assertedBalancedRhea 51076
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19,20-epoxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Left to right

→

Balance undeterminable

Rhea 51080

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 16,17-epoxy-(4Z,7Z,10Z,13Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51084

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 13,14-epoxy-(4Z,7Z,10Z,16Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51088

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 10,11-epoxy-(4Z,7Z,13Z,16Z,19Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51092

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19,20-epoxy-(7Z,10Z,13Z,16Z)-docosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51096

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 16,17-epoxy-(7Z,10Z,13Z,19Z)-docosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51100

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 13,14-epoxy-(7Z,10Z,16Z,19Z)-docosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51104

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 10,11-epoxy-(7Z,13Z,16Z,19Z)-docosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51108

(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy-(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 51112

guanosine(6) in tRNA + S-adenosyl-L-methionine = N(2)-methylguanosine(6) in tRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 51116

(8S,15S)-dihydroperoxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 AH2 = (8S,15S)-dihydroxy-(5Z,9E,11Z,13E)-eicosatetraenoate + 2 A + 2 H2O

Direction not assertedBalancedRhea 51120

uridine in snRNA = pseudouridine in snRNA

Direction not assertedBalancedRhea 51124

an aliphatic amine + A + H2O = an aldehyde + AH2 + NH4(+)

Direction not assertedBalance undeterminableRhea 51128

a purine 2'-deoxyribonucleoside 5'-phosphate + H2O = a purine nucleobase + 2-deoxy-D-ribose 5-phosphate

Direction not assertedBalance undeterminableRhea 51132

(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + 2 O2 = (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E,19Z)-docosahexaenoate

Direction not assertedBalancedRhea 51136

(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate + 2 O2 = (10,17S)-dihydroperoxy-(4Z,7Z,11Z,13Z,15E)-docosapentaenoate

Direction not assertedBalancedRhea 51140

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + 2 O2 = (10,17)-dihydroperoxy-(7Z,11Z,13Z,15E,19Z)-docosapentaenoate

Direction not assertedBalancedRhea 51144

2 oxidized [azurin] + a primary alcohol = 2 reduced [azurin] + an aldehyde + 2 H(+)

Direction not assertedBalance undeterminableRhea 51148

L-cysteinyl-[sulfatase] + 2 a thiol + O2 = an organic disulfide + 3-oxo-L-alanyl-[sulfatase] + hydrogen sulfide + H2O + H(+)

Direction not assertedBalance undeterminableRhea 51152

tRNA(Glu) + L-glutamate + ATP = L-glutamyl-tRNA(Gln) + AMP + diphosphate

Direction not assertedBalancedRhea 51156

cytidine(60) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(60) in tRNA(Asp) + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51160

cytidine(61) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(61) in tRNA(Asp) + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51164

(R)-adrenaline + O2 + H2O = (R)-3,4-dihydroxymandelaldehyde + methylamine + H2O2

Direction not assertedBalancedRhea 51168

cytidine(62) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(62) in tRNA(Asp) + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51172

cytidine(48) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(48) in tRNA(Asp) + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51176

cytidine(49) in tRNA(Asp) + S-adenosyl-L-methionine = 5-methylcytidine(49) in tRNA(Asp) + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 51180

1-octadecanoyl-sn-glycero-3-phosphoserine + H2O = sn-glycero-3-phospho-L-serine + octadecanoate + H(+)

Left to rightBalancedRhea 51184

superoxide + nitric oxide = peroxynitrite

Direction not assertedBalancedRhea 51188

(R)-2-hydroxyglutarate + NADP(+) = 2-oxoglutarate + NADPH + H(+)

Direction not assertedBalancedRhea 51192

serotonin(out) + chloride(out) + Na(+)(out) = serotonin(in) + chloride(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 51196

N-retinylidene-N-retinylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphate + H(+) = N-retinylidene-N-retinylphosphatidylethanolamine + H2O

Direction not assertedBalance undeterminableRhea 51200

6-trans-leukotriene B4 + NADP(+) = 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + NADPH + H(+)

Left to rightBalancedRhea 51204

20-hydroxy-leukotriene B4 + NADP(+) = 12-oxo-20-hydroxy-leukotriene B4 + NADPH + H(+)

Left to rightBalancedRhea 51208

(5S,12S)-dihydroxy-(6E,10E,12E,14Z)-eicosatetraenoate + NADP(+) = 12-oxo-(5S)-hydroxy-(6E,8E,10E,14Z)-eicosatetraenoate + NADPH + H(+)

Left to rightBalancedRhea 51212

3beta-hydroxyandrost-5-en-17-one + 3'-phosphoadenylyl sulfate = dehydroepiandrosterone 3-sulfate + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 51216

1-chloro-2,4-dinitrobenzene + glutathione = 2,4-dinitrophenyl-S-glutathione + chloride + H(+)

Left to rightBalancedRhea 51220

S-sulfanyl-L-cysteinyl-[SoxY protein] + thiosulfate + 2 Fe(III)-[cytochrome c] = S-(2-sulfodisulfanyl)-L-cysteinyl-[SoxY protein] + 2 Fe(II)-[cytochrome c] + 2 H(+)

Direction not assertedBalance undeterminableRhea 51224

17alpha-ethynylestradiol + 3'-phosphoadenylyl sulfate = 17alpha-ethynylestradiol 3-sulfate + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 51228

2-glyceryl-prostaglandin H2 = 2-glyceryl-prostaglandin D2

Left to rightBalancedRhea 51232

oxidized coenzyme F420-(gamma-L-Glu)(n) + GTP + L-glutamate = oxidized coenzyme F420-(gamma-L-Glu)(n+1) + GDP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 51236

(9Z,12Z)-octadecadienoate + O2 = (13R)-hydroperoxy-(9Z,11E)-octadecadienoate

Direction not assertedBalancedRhea 51240

(9Z,12Z,15Z)-octadecatrienoate + O2 = (13R)-hydroperoxy-(9Z,11E,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 51244

(9Z,12Z,15Z)-octadecatrienoate + O2 = (9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 51248

(9Z,12Z,15Z)-octadecatrienoate + O2 = (11R)-hydroperoxy-(9Z,12Z,15Z)-octadecatrienoate

Direction not assertedBalancedRhea 51252

(9S)-hydroperoxy-(10E,12Z,15Z)-octadecatrienoate + O2 = (9S,16S)-dihydroperoxy-(10E,12Z,14E)-octadecatrienoate

Direction not assertedBalancedRhea 51256

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