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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

2,101–2,150 of 18,558 reactions from Rhea

4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + NADH + H(+)
Direction not assertedBalancedRhea 18829
4-formylbenzenesulfonate + NAD(+) + H2O = 4-sulfobenzoate + NADH + 2 H(+)
Direction not assertedBalancedRhea 18833
10-deacetyltaxuyunnanin C + acetyl-CoA = taxuyunnanin C + CoA
Direction not assertedBalancedRhea 18837
(R)-glycerate + NADP(+) = 2-hydroxy-3-oxopropanoate + NADPH + H(+)
Direction not assertedBalancedRhea 18841
(R)-glycerate + NAD(+) = 2-hydroxy-3-oxopropanoate + NADH + H(+)
Direction not assertedBalancedRhea 18845
a 2'-unsubstituted isoflavone + reduced [NADPH--hemoprotein reductase] + O2 = a 2'-hydroxyisoflavone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 18849

tartrate + NAD(+) = 2-hydroxy-3-oxosuccinate + NADH + H(+)

Direction not assertedBalancedRhea 18853

lithocholate + reduced [NADPH--hemoprotein reductase] + O2 = 6beta-hydroxylithocholate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 18857

a 5-hydroxyfurocoumarin + S-adenosyl-L-methionine = a 5-methoxyfurocoumarin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 18861

N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + 2-methylpropanoyl-CoA = N(6)-[(R)-S(8)-2-methylpropanoyldihydrolipoyl]-L-lysyl-[protein] + CoA

Right to leftBalance undeterminableRhea 18865

L-xylulose + ATP = L-xylulose 5-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 18869

3-chloro-D-alanine + H2O = chloride + pyruvate + NH4(+) + H(+)

Direction not assertedBalancedRhea 18873

myo-inositol + S-adenosyl-L-methionine = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 18877

histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 18881

GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH + H(+)

Direction not assertedBalancedRhea 18885

D-glucose 6-phosphate + UDP-alpha-D-glucose = alpha,alpha-trehalose 6-phosphate + UDP + H(+)

Direction not assertedBalancedRhea 18889

a flavonol 3-O-beta-D-glucoside + UDP-alpha-D-glucose = a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside + UDP + H(+)

Direction not assertedBalance undeterminableRhea 18893

3,3',5'-triiodo-L-thyronine + iodide + A + H(+) = L-thyroxine + AH2

Right to leftBalancedRhea 18897

N-benzyloxycarbonyl-L-leucine + H2O + H(+) = benzyl alcohol + L-leucine + CO2

Direction not assertedBalancedRhea 18901

phosphonoacetaldehyde + H2O = acetaldehyde + phosphate + H(+)

Direction not assertedBalancedRhea 18905

2,4,6-trichlorophenol + S-adenosyl-L-methionine = 2,4,6-trichloroanisole + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 18909

a neolactoside nLc4Cer(d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a neolactoside IV(3)-alpha-NeuAc-nLc4Cer(d18:1(4E)) + CMP + H(+)

Left to rightBalance undeterminableRhea 18913

L-gulono-1,4-lactone + NADP(+) = D-glucurono-3,6-lactone + NADPH + H(+)

Direction not assertedBalancedRhea 18925

thiophene-2-carbonyl-CoA + AH2 + O2 = 5-hydroxythiophene-2-carbonyl-CoA + A + H2O + H(+)

Direction not assertedBalancedRhea 18929

(24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-en-26-oyl-CoA + H2O

Right to leftBalancedRhea 18933

an N-acyl-L-homoserine lactone + H2O = L-homoserine lactone + a carboxylate

Direction not assertedBalance undeterminableRhea 18937

a (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP(+) = a (3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 18941

L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2

Left to rightBalance undeterminableRhea 18945

taxa-4(20),11-dien-5alpha-ol + reduced [NADPH--hemoprotein reductase] + O2 = taxa-4(20),11-dien-5alpha,13alpha-diol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 18949

L-erythro-7,8-dihydrobiopterin + NADP(+) = L-sepiapterin + NADPH + H(+)

Right to leftBalancedRhea 18953

(4R)-limonene + reduced [NADPH--hemoprotein reductase] + O2 = (1R,5S)-carveol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 18957

D-allose + L-lysyl-[protein] = N(6)-(D-psicosyl)-L-lysyl-[protein] + H2O

Direction not assertedBalance undeterminableRhea 18961

hydroxymethylbilane = uroporphyrinogen III + H2O

Direction not assertedBalancedRhea 18965

a long-chain fatty acid + hnu + H(+) = a long-chain alkane + CO2

Direction not assertedBalance undeterminableRhea 18969

deacetoxyvindoline + 2-oxoglutarate + O2 = 4-O-deacetylvindoline + succinate + CO2

Direction not assertedBalancedRhea 18973

a quinone + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + a quinol

Left to rightBalance undeterminableRhea 18977

(R)-pantolactone + NADP(+) = 2-dehydropantolactone + NADPH + H(+)

Direction not assertedBalancedRhea 18981

chorismate = isochorismate

Direction not assertedBalancedRhea 18985

L-valine + H(+) = 2-methylpropan-1-amine + CO2

Direction not assertedBalancedRhea 18989

(9Z,12Z)-octadecadienoate + O2 = (11S)-hydroperoxy-(9Z,12Z)-octadecadienoate

Direction not assertedBalancedRhea 18993

phosphocholine + CTP + H(+) = CDP-choline + diphosphate

Left to rightBalancedRhea 18997

a 3-acylpyruvate + H2O = a carboxylate + pyruvate + H(+)

Direction not assertedBalance undeterminableRhea 19009

dTTP + H2O = dTDP + phosphate + H(+)

Direction not assertedBalancedRhea 19013

(6S)-NADHX + ATP = ADP + phosphate + NADH + H(+)

Direction not assertedBalancedRhea 19017

an alpha-L-fucosyl-(1->2)-beta-D-galactosyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-alpha-D-galactosaminyl-(1->3)-[alpha-L-fucosyl-(1->2)]-beta-D-galactosyl derivative + UDP + H(+)

Left to rightBalance undeterminableRhea 19021

L-aspartate + O2 + H2O = oxaloacetate + H2O2 + NH4(+)

Direction not assertedBalancedRhea 19025

urea-1-carboxylate + H2O + 3 H(+) = 2 NH4(+) + 2 CO2

Direction not assertedBalancedRhea 19029

an N-acyl-D-glucosamine = an N-acyl-D-mannosamine

ReversibleBalance undeterminableRhea 19033

an epoxide + H2O = an ethanediol

Left to rightBalance undeterminableRhea 19037

(25R)-cholest-5-ene-3beta,26-diol + reduced [NADPH--hemoprotein reductase] + O2 = (25R)-cholest-5-en-3beta,7alpha,26-triol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 19041

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