Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

20,851–20,900 of 31,435, by identifier

beta-D-galactosyl-(1<->1)-sphing-4-enine + H2O = sphing-4-enine + D-galactose
Left to rightBalancedRhea 43908
cholest-4-en-3-one + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (25R)-3-oxocholest-4-en-26-ol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Direction not assertedBalance undeterminableRhea 43912
(25R)-3-oxocholest-4-en-26-ol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = (25R)-3-oxocholest-4-en-26-al + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 H2O
Direction not assertedBalance undeterminableRhea 43916
(25R)-3-oxocholest-4-en-26-al + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) = (25R)-3-oxocholest-4-en-26-oate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Direction not assertedBalance undeterminableRhea 43920
pregnenolone + NAD(+) = pregn-5-ene-3,20-dione + NADH + H(+)
Left to rightBalancedRhea 43924
pregn-5-ene-3,20-dione = progesterone
Left to rightBalancedRhea

43928

3beta-hydroxyandrost-5-en-17-one + NAD(+) = androst-5-ene-3,17-dione + NADH + H(+)

Left to rightBalancedRhea 43932

androst-5-ene-3,17-dione = androst-4-ene-3,17-dione

Left to rightBalancedRhea 43936

3,7,11,15-tetramethylhexadecanoate + NADPH + O2 + H(+) = omega-hydroxy-3,7,11,15-tetramethyl-hexadecanoate + NADP(+) + H2O

Direction not assertedBalancedRhea 43952

15-methylhexadecanoate + NADPH + O2 + H(+) = omega-hydroxy-15-methyl-hexadecanoate + NADP(+) + H2O

Direction not assertedBalancedRhea 43956

a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA = a 1-acyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA

Left to rightBalance undeterminableRhea 43960

a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + octadecanoyl-CoA = 1-octadecanoyl-2-acyl-sn-glycero-3-phospho-1D-myo-inositol + CoA

Left to rightBalance undeterminableRhea 43964

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoate + H(+)

Left to rightBalancedRhea 43968

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = hexadecanoyl-glycero-3-phospho-(1D-myo-inositol) + hexadecanoate + H(+)

Direction not assertedBalancedRhea 43972

hexadecanoate + NADPH + O2 + H(+) = 14-hydroxyhexadecanoate + NADP(+) + H2O

Direction not assertedBalancedRhea 43976

hexadecanoate + NADPH + O2 + H(+) = 15-hydroxyhexadecanoate + NADP(+) + H2O

Direction not assertedBalancedRhea 43980

(2E,6E)-farnesol + NADPH + O2 + H(+) = (2E,6E)-omega-hydroxy-farnesol + NADP(+) + H2O

Direction not assertedBalancedRhea 43984

(2E,6E)-farnesyl diphosphate + NADPH + O2 + H(+) = (2E,6E)-omega-hydroxy-farnesyl diphosphate + NADP(+) + H2O

Direction not assertedBalancedRhea 43988

(2E,6E,10E)-geranylgeraniol + NADPH + O2 + H(+) = 16-hydroxy-(2E,6E,10E)-geranylgeraniol + NADP(+) + H2O

Direction not assertedBalancedRhea 43992

a 3-methyl fatty acyl-CoA + 2-oxoglutarate + O2 = a 2-hydroxy-3-methyl fatty acyl-CoA + succinate + CO2

Direction not assertedBalance undeterminableRhea 43996

3-methylhexadecanoyl-CoA + 2-oxoglutarate + O2 = 2-hydroxy-3-methylhexadecanoyl-CoA + succinate + CO2

Left to rightBalancedRhea 44000

3-methyl fatty acid + ATP + CoA = a 3-methyl fatty acyl-CoA + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 44004

a 2-methyl-branched fatty aldehyde + NAD(+) + H2O = a 2-methyl fatty acid + NADH + 2 H(+)

Direction not assertedBalance undeterminableRhea 44008

(9Z)-hexadecenoyl-[ACP] + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid IVA (E. coli) = (9Z)-hexadecenoyl-(Kdo)2-lipid IVA (E. coli) + holo-[ACP]

Direction not assertedBalance undeterminableRhea 44012

2,6,10,14-tetramethylpentadecanal + NAD(+) + H2O = 2,6,10,14-tetramethylpentadecanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 44016

octadecanal + NAD(+) + H2O = octadecanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 44020

(3R)-3-hydroxydodecanoyl-CoA = (2E)-dodecenoyl-CoA + H2O

Direction not assertedBalancedRhea 44024

L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H2O

Direction not assertedBalancedRhea 44028

9,10-epoxy-(12Z)-octadecenoate + H2O = 9,10-dihydroxy-(12Z)-octadecenoate

Left to rightBalancedRhea 44032

12,13-epoxy-(9Z)-octadecenoate + H2O = 12,13-dihydroxy-(9Z)-octadecenoate

Direction not assertedBalancedRhea 44036

14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoate + H2O = 14,15-dihydroxy-(5Z,8Z,11Z)-eicosatrienoate

Left to rightBalancedRhea 44040

11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + H2O = 11,12-dihydroxy-(5Z,8Z,14Z)-eicosatrienoate

Left to rightBalancedRhea 44044

8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoate + H2O = 8,9-dihydroxy-(5Z,11Z,14Z)-eicosatrienoate

Left to rightBalancedRhea 44048

alpha,alpha-trehalose + hexadecanoyl-CoA = 2-O-hexadecanoyl-alpha,alpha-trehalose + CoA

Direction not assertedBalancedRhea 44052

2-O-hexadecanoyl-alpha,alpha-trehalose + hexadecanoyl-CoA = 2-O,3-O-dihexadecanoyl-alpha,alpha-trehalose + CoA

Direction not assertedBalancedRhea 44056

2-O-sulfo-alpha,alpha-trehalose + hexadecanoyl-CoA = 2-O-sulfo-2'-O-hexadecanoyl-alpha,alpha-trehalose + CoA

Direction not assertedBalancedRhea 44060

octan-1-ol + hexadecanoyl-CoA = octyl hexadecanoate + CoA

Direction not assertedBalancedRhea 44064

a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + H2O = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 44068

1-O-alkyl-2-acyl-sn-glycerol + ATP = 1-O-alkyl-2-acyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalance undeterminableRhea 44072

pentadecanoate + ATP + CoA = pentadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44076

undecanoate + ATP + CoA = undecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44080

heptadecanoate + ATP + CoA = heptadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44084

heptanoate + ATP + CoA = heptanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44088

nonadecanoate + ATP + CoA = nonadecanoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 44092

decan-1-ol + hexadecanoyl-CoA = decyl hexadecanoate + CoA

Direction not assertedBalancedRhea 44096

octanal + NAD(+) + H2O = octanoate + NADH + 2 H(+)

Left to rightBalancedRhea 44100

decanal + NAD(+) + H2O = decanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 44104

heptanal + NAD(+) + H2O = heptanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 44108

nonan-1-ol + hexadecanoyl-CoA = nonyl hexadecanoate + CoA

Direction not assertedBalancedRhea 44112

eicosan-1-ol + hexadecanoyl-CoA = eicosyl hexadecanoate + CoA

Direction not assertedBalancedRhea 44116

Page 418 of 629