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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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AssessmentsRegulatory determinations, transcribed
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

20,751–20,800 of 31,435, by identifier

2,5-diformylfuran + H2O = 2-(dihydroxymethyl)-5-formylfuran
Direction not assertedBalancedRhea 43508
2-(dihydroxymethyl)-5-formylfuran + O2 = 2-carboxy-5-formylfuran + H2O2 + H(+)
Direction not assertedBalancedRhea 43512
2-carboxy-5-formylfuran + H2O = 2-carboxy-5-(dihydroxymethyl)furan
Direction not assertedBalancedRhea 43516
2-carboxy-5-(dihydroxymethyl)furan + O2 = 2,5-dicarboxyfuran + H2O2 + H(+)
Direction not assertedBalancedRhea 43520
L-allo-threonine + NADP(+) = aminoacetone + CO2 + NADPH
Direction not assertedBalancedRhea 43524
L-serine + NAD(+) = 2-aminomalonate semialdehyde + NADH + H(+)
Direction not assertedBalancedRhea 43528
a ribonucleoside 3',5'-bisphosphate + H2O = a ribonucleoside 5'-phosphate + phosphate

Direction not assertedBalance undeterminableRhea 43532

2 D-glyceraldehyde 3-phosphate = 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + phosphate + 2 H2O

Direction not assertedBalancedRhea 43536

L-seryl-[isocitrate dehydrogenase] + ATP = O-phospho-L-seryl-[isocitrate dehydrogenase] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 43540

tyramine + L-glutamate + ATP = gamma-L-glutamyltyramine + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 43544

1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate

ReversibleBalancedRhea 43548

1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dioctanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate

Left to rightBalancedRhea 43552

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4-bisphosphate) + phosphate

Left to rightBalancedRhea 43556

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + phosphate

Left to rightBalancedRhea 43560

4-(hydroxymethyl)-2-furancarboxaldehyde phosphate + L-alanine = [5-(aminomethyl)-3-furyl]methyl phosphate + pyruvate

Direction not assertedBalancedRhea 43564

3,6-anhydro-alpha-L-galactopyranose + NAD(+) + H2O = 3,6-anhydro-L-galactonate + NADH + 2 H(+)

Direction not assertedBalancedRhea 43568

D-arginine + A + H2O = 5-guanidino-2-oxopentanoate + AH2 + NH4(+)

Direction not assertedBalancedRhea 43572

1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + H2O = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol-4-phosphate) + phosphate

Direction not assertedBalancedRhea 43576

D-arginine + A = iminoarginine + AH2

Direction not assertedBalancedRhea 43580

iminoarginine + H2O = 5-guanidino-2-oxopentanoate + NH4(+)

Direction not assertedBalancedRhea 43584

a globoside NORint + UDP-alpha-D-galactose = a globoside NOR2 + UDP + H(+)

Direction not assertedBalance undeterminableRhea 43588

all-trans-zeaxanthin + O2 = (3R)-3-hydroxy-8'-apo-beta-carotenal + 3beta-hydroxy-beta-cyclocitral

Direction not assertedBalancedRhea 43592

(3R)-3-hydroxy-8'-apo-beta-carotenal + O2 = crocetin dialdehyde + 3beta-hydroxy-beta-cyclocitral

Direction not assertedBalancedRhea 43596

3-oxoeicosanoyl-[ACP] + NADPH + H(+) = 3R-hydroxyeicosanoyl-[ACP] + NADP(+)

Direction not assertedBalance undeterminableRhea 43600

(2E)-4-hydroxy-3-methylbut-2-enyl diphosphate + oxidized [flavodoxin] + H2O + 2 H(+) = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + reduced [flavodoxin]

Direction not assertedBalance undeterminableRhea 43604

cytidine(34) in tRNA(Ile2) + agmatine + ATP + H2O = 2-agmatinylcytidine(34) in tRNA(Ile2) + AMP + 2 phosphate + 2 H(+)

Direction not assertedBalancedRhea 43608

uridine(341) in tmRNA + S-adenosyl-L-methionine = 5-methyluridine(341) in tmRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 43612

[molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly + ATP + H(+) = [molybdopterin-synthase sulfur-carrier protein]-C-terminal Gly-Gly-AMP + diphosphate

Direction not assertedBalance undeterminableRhea 43616

L-serine + NADP(+) = aminoacetaldehyde + CO2 + NADPH

Direction not assertedBalancedRhea 43620

2-aminomalonate semialdehyde + H(+) = aminoacetaldehyde + CO2

Direction not assertedBalancedRhea 43624

L-serine + NAD(+) = aminoacetaldehyde + CO2 + NADH

Direction not assertedBalancedRhea 43628

L-phenylalanyl-tRNA(Phe) + an N-terminal L-alpha-aminoacyl-[protein] = an N-terminal L-phenylalanyl-L-alpha-aminoacyl-[protein] + tRNA(Phe)

Direction not assertedBalance undeterminableRhea 43632

N(6)-acetyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-acetyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]

Left to rightBalance undeterminableRhea 43636

malonyl-[ACP] + dodecanoyl-CoA + H(+) = 3-oxotetradecanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 43640

malonyl-[ACP] + tetradecanoyl-CoA + H(+) = 3-oxohexadecanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 43644

malonyl-[ACP] + hexadecanoyl-CoA + H(+) = 3-oxooctadecanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 43648

decanoyl-CoA + malonyl-[ACP] + H(+) = 3-oxododecanoyl-[ACP] + CO2 + CoA

Direction not assertedBalance undeterminableRhea 43652

1,2-di-(9Z-octadecenoyl)-sn-glycerol + CTP = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CDP + H(+)

Direction not assertedBalancedRhea 43656

propanoyl-CoA + hydrogencarbonate + ATP = methylmalonyl-CoA + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 43660

tetracosanoyl-CoA + hydrogencarbonate + ATP = 2-carboxytetracosanoyl-CoA + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 43664

hexacosanoyl-CoA + hydrogencarbonate + ATP = 2-carboxyhexacosanoyl-CoA + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 43668

1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + CoA

Left to rightBalancedRhea 43672

1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + (9Z)-octadecenoyl-CoA = 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phospho]-glycerol + CoA

Left to rightBalancedRhea 43676

1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA = 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-2-hexadecanoyl-sn-glycero-3-phospho]-glycerol + CoA

Left to rightBalancedRhea 43680

L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + phosphate + ATP = N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + AMP + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 43684

N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + pyruvate = L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + phosphoenolpyruvate

Direction not assertedBalance undeterminableRhea 43688

N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + ADP = N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 43692

N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase] + phosphate + H(+) = N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] + diphosphate

Direction not assertedBalance undeterminableRhea 43696

(2E,6E)-farnesoate + S-adenosyl-L-methionine = methyl (2E,6E)-farnesoate + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 43700

tetradecanoate + ATP + H(+) = tetradecanoyl-AMP + diphosphate

Direction not assertedBalancedRhea 43704

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