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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

19,951–20,000 of 31,435, by identifier

(3R)-hydroxyhexadecanedioyl-CoA + NAD(+) = 3-oxohexadecanedioyl-CoA + NADH + H(+)
Left to rightBalancedRhea 40263
(3S)-hydroxyhexadecanedioyl-CoA + NAD(+) = 3-oxohexadecanedioyl-CoA + NADH + H(+)
Left to rightBalancedRhea 40267
tetradecanedioyl-CoA + O2 = (2E)-tetradecenedioyl-CoA + H2O2
Direction not assertedBalancedRhea 40271
hexadecanedioyl-CoA + O2 = (2E)-hexadecenedioyl-CoA + H2O2
Left to rightBalancedRhea 40275
dodecanoyl-CoA + (R)-carnitine = O-dodecanoyl-R-carnitine + CoA
Direction not assertedBalancedRhea 40279
hexadecanedioyl-CoA + (R)-carnitine = O-hexadecanedioyl-L-carnitine + CoA
Direction not assertedBalancedRhea 40283
decanedioate + ATP + CoA = decanedioyl-CoA + AMP + diphosphate

? Direction not asserted

Balanced

Rhea 40287

tetradecanedioate + ATP + CoA = tetradecanedioyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 40291

hexadecanedioate + ATP + CoA = hexadecanedioyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 40295

6-deoxyerythronolide B + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = erythronolide B + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 40299

dodecanedioyl-CoA + A = (2E)-dodecenedioyl-CoA + AH2

Direction not assertedBalancedRhea 40303

decanedioyl-CoA + A = (2E)-decenedioyl-CoA + AH2

Direction not assertedBalancedRhea 40307

hexanoyl-CoA + O2 = (2E)-hexenoyl-CoA + H2O2

Left to rightBalancedRhea 40311

glutaryl-CoA + O2 = (2E)-glutaconyl-CoA + H2O2

Left to rightBalancedRhea 40315

tetracosanoyl-CoA + O2 = (2E)-tetracosenoyl-CoA + H2O2

Left to rightBalancedRhea 40319

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40323

1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40327

1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + ATP = 1-eicosanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40331

1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40335

1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycerol + ATP = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40339

3-oxohexadecanedioyl-CoA + CoA = tetradecanedioyl-CoA + acetyl-CoA

Left to rightBalancedRhea 40343

3-oxotetradecanedioyl-CoA + CoA = dodecanedioyl-CoA + acetyl-CoA

Direction not assertedBalancedRhea 40347

1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycerol + ATP = 1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40351

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycerol + ATP = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40355

1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycerol + ATP = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40359

1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)

Left to rightBalancedRhea 40363

1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 4-phosphate + ATP = 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 4,5-bisphosphate + ADP + H(+)

Left to rightBalancedRhea 40367

alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + ATP = 3-O-phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-di-trans,octa-cis-undecaprenyl diphosphate + ADP + H(+)

Direction not assertedBalance undeterminableRhea 40371

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate + ADP + H(+)

Left to rightBalancedRhea 40375

1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol + ATP = 1-octadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate + ADP + H(+)

Left to rightBalancedRhea 40379

1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho-1D-myo-inositol + ATP = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate + ADP + H(+)

Left to rightBalancedRhea 40383

1,2-di-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho-1D-myo-inositol + ATP = 1,2-di(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho-1D-myo-inositol 5-phosphate + ADP + H(+)

Left to rightBalancedRhea 40387

1-O-alkyl-2-acyl-sn-glycerol + an acyl-CoA = 1-O-alkyl-2,3-diacyl-sn-glycerol + CoA

Direction not assertedBalance undeterminableRhea 40391

1,2-dihydro-beta-NAD + O2 + H(+) = H2O2 + NAD(+)

Direction not assertedBalancedRhea 40395

1,2-dihydro-beta-NADP + O2 + H(+) = H2O2 + NADP(+)

Direction not assertedBalancedRhea 40399

1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycerol + ATP = 1-O-hexadecyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40403

1-O-hexadecyl-2-(9Z-octadecenoyl)-sn-glycerol + ATP = 1-O-hexadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+)

Left to rightBalancedRhea 40407

1,2-dihexadecanoyl-sn-glycero-3-CDP + myo-inositol = 1,2-dihexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)

Direction not assertedBalancedRhea 40411

pristanoyl-CoA + H2O = 2,6,10,14-tetramethylpentadecanoate + CoA + H(+)

Left to rightBalancedRhea 40415

phytanoyl-CoA + H2O = 3,7,11,15-tetramethylhexadecanoate + CoA + H(+)

Left to rightBalancedRhea 40419

(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O

Direction not assertedBalance undeterminableRhea 40423

1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

Left to rightBalancedRhea 40427

1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-hexadecanoyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

Left to rightBalancedRhea 40431

1-hexadecanoyl-sn-glycero-3-phosphocholine + H2O = sn-glycerol 3-phosphocholine + hexadecanoate + H(+)

Left to rightBalancedRhea 40435

6-sulfo-beta-D-quinovose = 6-deoxy-6-sulfo-D-fructose

Direction not assertedBalancedRhea 40439

6-deoxy-6-sulfo-D-fructose + ATP = 6-deoxy-6-sulfo-D-fructose 1-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 40443

(2R)-pristanoyl-CoA = (2S)-pristanoyl-CoA

Direction not assertedBalancedRhea 40447

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

Left to rightBalancedRhea 40451

(25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA = (25S)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA

ReversibleBalancedRhea 40455

(2S)-pristanoyl-CoA + O2 = (2E)-pristenoyl-CoA + H2O2

Left to rightBalancedRhea 40459

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