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Subsystem: Leukotriene metabolism Remove
151–170 of 170 reactions in Leukotriene metabolism
10,11-dihydro-12-epi-LTB4[c] = 10,11-dihydro-LTB4[c]
ReversibleBalancedHuman-GEM MAR01285
H+[x] + leukotriene E4[x] + NADPH[x] + O2[x] = 20-hydroxy-LTE4[x] + H2O[x] + NADP+[x]
Left to rightBalancedEC 1.14.13.34Human-GEM MAR01287
20-hydroxy-LTE4[x] + NAD+[x] = 20-oxo-LTE4[x] + H+[x] + NADH[x]
Left to rightBalancedEC 1.1.1.1Human-GEM MAR01288
20-oxo-LTE4[x] + H2O[x] + NAD+[x] = 20-COOH-LTE4[x] + 2 H+[x] + NADH[x]
Left to rightBalancedEC 1.2.1.3Human-GEM MAR01289
20-COOH-LTE4[x] + ATP[x] + CoA[x] = 20-COOH-LTE4-CoA[x] + AMP[x] + PPi[x]
Left to rightBalancedEC 6.2.1.3
20-COOH-LTE4-CoA[x] + FAD[x] = (18E)-20-oxo-20-CoA-LTE4[x] + FADH2[x]
Left to rightBalancedEC 1.3.3.6Human-GEM MAR01291
(18E)-20-oxo-20-CoA-LTE4[x] + H2O[x] = 18(R)-hydroxy-20-oxo-20-CoA-LTE4[x]
Left to rightBalancedEC 4.2.1.17Human-GEM MAR01292
18(R)-hydroxy-20-oxo-20-CoA-LTE4[x] + NAD+[x] = 20-COOH-18-oxo-LTE4-CoA[x] + H+[x] + NADH[x]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Human-GEM MAR01293
20-COOH-18-oxo-LTE4-CoA[x] + CoA[x] = acetyl-CoA[x] + omega-COOH-dinor-LTE4-CoA[x]
Left to rightBalancedEC 2.3.1.16Human-GEM MAR01294
18-COOH-LTE4[x] + CoA[x] + H+[x] = H2O[x] + omega-COOH-dinor-LTE4-CoA[x]
ReversibleBalancedEC 3.1.2.2Human-GEM MAR01295
FAD[x] + omega-COOH-dinor-LTE4-CoA[x] = 18-COOH-(16E)-dinor-LTE5-CoA[x] + FADH2[x]
Left to rightBalancedEC 1.3.3.6Human-GEM MAR01296
18-COOH-(15E)-dinor-LTE4-CoA[x] + NADP+[x] = 18-COOH-(16E)-dinor-LTE5-CoA[x] + H+[x] + NADPH[x]
ReversibleBalancedEC 1.3.1.34Human-GEM MAR01297
16e-18-oxo-18-CoA-dinor-LTE4[x] = 18-COOH-(15E)-dinor-LTE4-CoA[x]
ReversibleBalancedEC 5.3.3.8Human-GEM MAR01298
16e-18-oxo-18-CoA-dinor-LTE4[x] + H2O[x] = 16(S)-hydroxy-18-oxo-18-CoA-LTE4[x]
Left to rightBalancedEC 4.2.1.17Human-GEM MAR01299
16(S)-hydroxy-18-oxo-18-CoA-LTE4[x] + NAD+[x] = 16,18-oxo-18-CoA-dinor-LTE4[x] + H+[x] + NADH[x]
Left to rightBalancedEC 1.1.1.35, 1.1.1.211Human-GEM MAR01300
16e-18-oxo-18-CoA-dinor-LTE4[x] + CoA[x] + H2O[x] = acetyl-CoA[x] + 5 H+[x] + omega-COOH-tetranor-LTE3-CoA[x]
Left to rightUnbalancedEC 2.3.1.16Human-GEM MAR01301
H+[x] + H2O[x] + omega-COOH-tetranor-LTE3-CoA[x] = CoA[x] + omega-COOH-tetranor-LTE3[x]
Left to rightUnbalancedEC 3.1.2.27, 2.3.1.65Human-GEM MAR01302
FAD[x] + 3 H+[x] + omega-COOH-tetranor-LTE3-CoA[x] = (13E)-tetranor-16-oxo-16-CoA-LTE4[x] + FADH2[x]
Left to rightUnbalancedEC 1.3.3.6Human-GEM MAR01303
(13E)-tetranor-16-oxo-16-CoA-LTE4[x] + H2O[x] = (13E)-tetranor-16-carboxy-LTE4[x] + CoA[x] + H+[x]
Left to rightBalancedEC 3.1.2.2Human-GEM MAR01304
H2O[c] + leukotriene C4[c] = glutamate[c] + LTD4[c]
Left to rightBalancedEC 2.3.2.2Human-GEM MAR04796