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Subsystem: Bile acid biosynthesis Remove
151–200 of 256 reactions in Bile acid biosynthesis
5beta-cholestane-3alpha,7alpha-diol[m] + 2 NADP+[m] = 7alpha-hydroxycholest-4-en-3-one[m] + 2 H+[m] + 2 NADPH[m]
ReversibleBalancedEC 1.1.1.50Human-GEM MAR02895
5beta-cholestane-3alpha,7alpha,12alpha,25-tetrol[c] + H+[c] + NADPH[c] + O2[c] = 5beta-cholestane-3alpha,7alpha,12alpha,24r,25-pentol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.55Human-GEM MAR02933
5beta-cholestane-3alpha,7alpha,12alpha,25-tetrol[c] + H+[c] + NADPH[c] + O2[c] = 5beta-cholestane-3alpha,7alpha,12alpha,25,27-pentol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.55Human-GEM MAR02934
5beta-cholestane-3alpha,7alpha-diol[c] + H+[c] + NADPH[c] + O2[c] = 5beta-cholestane-3alpha,7alpha,27-triol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.1.1.1Human-GEM MAR02935
26-hydroxycholesterol[c] + NADP+[c] = 3beta-hydroxy-5-cholestenal[c] + H+[c] + NADPH[c]
ReversibleBalancedEC 5.3.3.1Human-GEM MAR02936
3beta-hydroxy-5-cholestene-27-oate[c] + H+[c] + NADPH[c] + O2[c] = 3beta,7alpha-dihydroxy-5-cholestenoate[c] + H2O[c] + NADP+[c]
Left to rightBalancedHuman-GEM MAR02937
3beta,7alpha-dihydroxy-5-cholestenoate[c] + NADP+[c] = 7alpha-hydroxy-3-oxo-4-cholestenoic acid[c] + H+[c] + NADPH[c]
ReversibleBalancedHuman-GEM MAR02938
3beta-hydroxy-5-cholestenal[c] + H2O[c] + NADP+[c] = 3beta-hydroxy-5-cholestene-27-oate[c] + 2 H+[c] + NADPH[c]
ReversibleBalancedEC 1.14.14.55Human-GEM MAR02939
chenodeoxycholoyl-CoA[m] + H2O[m] = chenodiol[m] + CoA[m] + H+[m]
ReversibleBalancedEC 3.1.2.2Human-GEM MAR02940
25(R)DHCA-CoA[c] + CoA[c] + O2[c] = chenodeoxycholoyl-CoA[c] + H2O[c] + propanoyl-CoA[c]
Left to rightBalancedEC 2.3.1.176Human-GEM MAR02941
25(R)DHCA-CoA[m] + CoA[m] + O2[m] = chenodeoxycholoyl-CoA[m] + H2O[m] + propanoyl-CoA[m]
ReversibleBalancedEC 2.3.1.176Human-GEM MAR02950
25(R)DHCA-CoA[x] + CoA[x] + O2[x] = chenodeoxycholoyl-CoA[x] + H2O[x] + propanoyl-CoA[x]
Left to rightBalancedEC 2.3.1.176Human-GEM MAR02953
5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol[m] + NAD+[m] = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al[m] + H+[m] + NADH[m]
ReversibleBalancedEC 1.14.14.55Human-GEM MAR03209
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al[c] + H2O[c] + NADP+[c] = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate[c] + 2 H+[c] + NADPH[c]
ReversibleBalancedHuman-GEM MAR03210
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al[m] + H2O[m] + NADP+[m] = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate[m] + 2 H+[m] + NADPH[m]
ReversibleBalancedEC 1.14.15.15Human-GEM MAR03214
cholest-5-ene-3beta,7alpha,27-triol[c] + H+[c] + 2 NADPH[c] + 2 O2[c] = 3beta,7alpha-dihydroxy-5-cholestenoate[c] + 3 H2O[c] + 2 NADP+[c]
Left to rightBalancedEC 2.1.1.13Human-GEM MAR03216
5beta-cholestane-3alpha,7alpha,12alpha,24s,25-pentol[c] + NADP+[c] = 3alpha,7alpha,12alpha,25-tetrahydroxy-5beta-cholestane-24-one[c] + H+[c] + NADPH[c]
ReversibleBalancedEC 1.11.1.7Human-GEM MAR03217
26-hydroxycholesterol[m] + NAD+[m] = 7alpha-hydroxycholest-4-en-3-one[m] + H+[m] + NADH[m]
ReversibleBalancedEC 3.5.1.14Human-GEM MAR03259
5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol[c] + H+[c] + NADPH[c] + O2[c] = 5beta-cholestane-3alpha,7alpha,12alpha,27,27-pentaol[c] + H2O[c] + NADP+[c]
Left to rightBalancedHuman-GEM MAR03766
5beta-cholestane-3alpha,7alpha,12alpha,26-tetrol[m] + H+[m] + NADPH[m] + O2[m] = 5beta-cholestane-3alpha,7alpha,12alpha,27,27-pentaol[m] + H2O[m] + NADP+[m]
Left to rightBalancedEC 1.14.15.15Human-GEM MAR03768
5beta-cholestane-3alpha,7alpha,12alpha,27,27-pentaol[c] = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al[c] + H2O[c]
ReversibleBalancedHuman-GEM MAR03774
H2O[m] + propanoyl-CoA[m] = CoA[m] + H+[m] + propanoate[m]
Left to rightBalancedEC 3.1.2.2Human-GEM MAR03799
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate[c] + 2 H+[c] + NADH[c] = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al[c] + H2O[c] + NAD+[c]
ReversibleBalancedEC 1.2.1.3Human-GEM MAR03815
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate[m] + 2 H+[m] + NADH[m] = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al[m] + H2O[m] + NAD+[m]
Left to rightBalancedEC 1.2.1.3Human-GEM MAR03817
3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate[r] + 2 H+[r] + NADH[r] = 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al[r] + H2O[r] + NAD+[r]
ReversibleBalancedEC 1.2.1.3Human-GEM MAR03821
cysteine[c] + O2[c] = 3-sulfinoalanine[c] + 2 H+[c]
Left to rightBalancedEC 1.13.11.20Human-GEM MAR03908
3-sulfinoalanine[c] + 2 H+[c] = CO2[c] + hypotaurine[c]
Left to rightBalancedEC 4.1.1.15, 4.1.1.29Human-GEM MAR03910
H+[c] + NADH[c] + taurine[c] = H2O[c] + hypotaurine[c] + NAD+[c]
BlockedBalancedHuman-GEM MAR03911
cysteamine[c] + O2[c] = H+[c] + hypotaurine[c]
Left to rightBalancedEC 1.13.11.19Human-GEM MAR04679
2 3-sulfinoalanine[c] + 2 H+[c] + O2[c] = 2 L-cysteate[c]
Left to rightBalancedHuman-GEM MAR08063
2 3-sulfinoalanine[m] + 2 H+[m] + O2[m] = 2 L-cysteate[m]
Left to rightBalancedHuman-GEM MAR08064
H+[c] + L-cysteate[c] = CO2[c] + taurine[c]
Left to rightBalancedEC 4.1.1.15, 4.1.1.29Human-GEM MAR08065
2 hypotaurine[c] + O2[c] = 2 taurine[c]
BlockedBalancedHuman-GEM MAR08759
deoxycholoyl-CoA[c] + glycine[c] = CoA[c] + glycodeoxycholate[c]
Left to rightBalancedHuman-GEM MAR10069
ATP[c] + CoA[c] + alpha-muricholic acid[c] = AMP[c] + PPi[c] + alpha-muricholoyl-CoA[c]
Left to rightBalancedHuman-GEM MAR10080
H2O[c] + alpha-muricholoyl-CoA[c] = CoA[c] + H+[c] + alpha-muricholic acid[c]
Left to rightBalancedHuman-GEM MAR10092
taurine[c] + alpha-muricholoyl-CoA[c] = CoA[c] + H+[c] + tauro-alpha-muricholic acid[c]
Left to rightBalancedHuman-GEM MAR10093
ATP[c] + CoA[c] + beta-muricholic acid[c] = AMP[c] + PPi[c] + beta-muricholoyl-CoA[c]
Left to rightBalancedEC 6.2.1.7Human-GEM MAR10094
H2O[c] + beta-muricholoyl-CoA[c] = CoA[c] + H+[c] + beta-muricholic acid[c]
Left to rightBalancedHuman-GEM MAR10095
taurine[c] + beta-muricholoyl-CoA[c] = CoA[c] + H+[c] + tauro-beta-muricholic acid[c]
Left to rightBalancedHuman-GEM MAR10096
ATP[c] + CoA[c] + omega-muricholic acid[c] = AMP[c] + PPi[c] + omega-muricholoyl-CoA[c]
Left to rightBalancedEC 6.2.1.7Human-GEM MAR10097
H2O[c] + omega-muricholoyl-CoA[c] = CoA[c] + H+[c] + omega-muricholic acid[c]
Left to rightBalancedHuman-GEM MAR10098
taurine[c] + omega-muricholoyl-CoA[c] = CoA[c] + H+[c] + tauro-omega-muricholic acid[c]
Left to rightBalancedHuman-GEM MAR10099
ATP[c] + CoA[c] + hyocholic acid[c] = AMP[c] + PPi[c] + hyocholoyl-CoA[c]
Left to rightBalancedEC 6.2.1.7Human-GEM MAR10105
H2O[c] + hyocholoyl-CoA[c] = CoA[c] + H+[c] + hyocholic acid[c]
Left to rightBalancedHuman-GEM MAR10106
taurine[c] + hyocholoyl-CoA[c] = CoA[c] + H+[c] + taurohyocholic acid[c]
Left to rightBalancedHuman-GEM MAR10107
glycine[c] + hyocholoyl-CoA[c] = CoA[c] + H+[c] + glycohyocholic acid[c]
Left to rightBalancedHuman-GEM MAR10108
ATP[c] + CoA[c] + dehydrocholic acid[c] = AMP[c] + PPi[c] + dehydrocholoyl-CoA[c]
Left to rightBalancedEC 6.2.1.7Human-GEM MAR10111
H2O[c] + dehydrocholoyl-CoA[c] = CoA[c] + H+[c] + dehydrocholic acid[c]
Left to rightBalancedHuman-GEM MAR10112
taurine[c] + dehydrocholoyl-CoA[c] = CoA[c] + H+[c] + taurodehydrocholic acid[c]
Left to rightBalancedHuman-GEM MAR10113