Loading the page.
Subsystem: Drug metabolism Remove
151–200 of 572 reactions in Drug metabolism
ATP[c] + H2O[c] + 7-hydroxy-3-alpha-iso-pravastatin[c] = ADP[c] + H+[c] + Pi[c] + 7-hydroxy-3-alpha-iso-pravastatin[e]
Left to rightBalancedTransportHuman-GEM MAR12458
7-hydroxy-3-alpha-iso-pravastatin[c] = 7-hydroxy-3-alpha-iso-pravastatin[e]
ReversibleBalancedTransportHuman-GEM MAR12459
H+[e] + allopurinol[e] = H+[c] + allopurinol[c]
Left to rightBalancedTransportHuman-GEM MAR12460
ATP[c] + H2O[c] + acetaminophen/paracetamol[c] = ADP[c] + H+[c] + Pi[c] + acetaminophen/paracetamol[e]
Left to rightBalancedTransportEC 7.6.2.2Human-GEM MAR12461
UDP-glucuronate[r] + acetaminophen/paracetamol[r] = H+[r] + UDP[r] + Acetaminophen glucuronide[r]
acetaminophen-glutathione-conjugate[e] = acetaminophen-glutathione-conjugate[c]
ReversibleBalancedTransportHuman-GEM MAR12463
ATP[c] + H2O[c] + acetaminophen-glutathione-conjugate[c] = ADP[c] + H+[c] + Pi[c] + acetaminophen-glutathione-conjugate[e]
Left to rightBalancedTransportHuman-GEM MAR12464
ATP[c] + H2O[c] + acetaminophen-glutathione-conjugate[e] = ADP[c] + H+[c] + Pi[c] + acetaminophen-glutathione-conjugate[c]
Left to rightBalancedTransportHuman-GEM MAR12465
ATP[c] + H2O[c] + Acetaminophen glucuronide[c] = ADP[c] + H+[c] + Pi[c] + Acetaminophen glucuronide[e]
Left to rightBalancedTransportHuman-GEM MAR12466
ATP[c] + H2O[c] + Acetaminophen glucuronide[e] = ADP[c] + H+[c] + Pi[c] + Acetaminophen glucuronide[c]
Left to rightBalancedTransportHuman-GEM MAR12467
PAPS[c] + acetaminophen/paracetamol[c] = H+[c] + PAP[c] + sulphate-conjugate-acetaminophen[c]
Left to rightBalancedEC 2.8.2.1Human-GEM MAR12468
acetaminophen/paracetamol[e] = acetaminophen/paracetamol[c]
ReversibleBalancedTransportHuman-GEM MAR12469
ATP[c] + H2O[c] + acetaminophen/paracetamol[e] = ADP[c] + H+[c] + Pi[c] + acetaminophen/paracetamol[c]
Left to rightBalancedTransportHuman-GEM MAR12470
Na+[e] + allopurinol[e] = Na+[c] + allopurinol[c]
Left to rightBalancedTransportHuman-GEM MAR12471
H2O[c] + O2[c] + allopurinol[c] = H2O2[c] + oxypurinol[c]
Left to rightBalancedEC 1.17.3.2, 1.2.3.1Human-GEM MAR12472
allopurinol[e] = allopurinol[c]
ReversibleBalancedTransportHuman-GEM MAR12473
H+[r] + NADPH[r] + O2[r] + AM1 (cyclosporine)[r] = H2O[r] + NADP+[r] + AM19 (cyclosporine)[r]
Left to rightBalancedEC 1.14.13.-, 1.14.14.1Human-GEM MAR12474
H+[r] + NADPH[r] + O2[r] + AM9 (cyclosporine)[r] = H2O[r] + NADP+[r] + AM19 (cyclosporine)[r]
Left to rightBalancedHuman-GEM MAR12475
ATP[c] + H2O[c] + AM19 (cyclosporine)[c] = ADP[c] + H+[c] + Pi[c] + AM19 (cyclosporine)[e]
Left to rightBalancedTransportHuman-GEM MAR12476
H+[c] + SAH[c] + AM1A (cyclosporine)[c] = SAM[c] + AM1A4N (cyclosporine)[c]
Left to rightBalancedHuman-GEM MAR12477
ATP[c] + H2O[c] + AM1A4N (cyclosporine)[c] = ADP[c] + H+[c] + Pi[c] + AM1A4N (cyclosporine)[e]
Left to rightBalancedTransportHuman-GEM MAR12478
O2[r] + AM1c (cyclosporine)[r] = H+[r] + H2O[r] + AM1Ac (cyclosporine)[r]
Left to rightBalancedHuman-GEM MAR12479
AM1Ac (cyclosporine)[c] = AM1Ac (cyclosporine)[e]
ReversibleBalancedTransportHuman-GEM MAR12480
NADPH[r] + O2[r] + AM1AL (cyclosporine)[r] = H2O[r] + NADP+[r] + AM1A (cyclosporine)[r]
Left to rightBalancedHuman-GEM MAR12481
ATP[c] + H2O[c] + AM1A (cyclosporine)[c] = ADP[c] + H+[c] + Pi[c] + AM1A (cyclosporine)[e]
Left to rightBalancedTransportHuman-GEM MAR12482
AM1A (cyclosporine)[c] = AM1A (cyclosporine)[e]
ReversibleBalancedTransportHuman-GEM MAR12483
NADP+[c] + AM1 (cyclosporine)[c] = H+[c] + NADPH[c] + AM1AL (cyclosporine)[c]
Left to rightBalancedHuman-GEM MAR12484
ATP[c] + H2O[c] + AM1AL (cyclosporine)[c] = ADP[c] + H+[c] + Pi[c] + AM1AL (cyclosporine)[e]
Left to rightBalancedTransportHuman-GEM MAR12485
AM1AL (cyclosporine)[c] = AM1AL (cyclosporine)[e]
ReversibleBalancedTransportHuman-GEM MAR12486
H+[c] + SAH[c] + AM1c9 (cyclosporine)[c] = SAM[c] + AM1c4N9 (cyclosporine)[c]
Left to rightBalancedHuman-GEM MAR12487
ATP[c] + H2O[c] + AM1c4N9 (cyclosporine)[c] = ADP[c] + H+[c] + Pi[c] + AM1c4N9 (cyclosporine)[e]
Left to rightBalancedTransportHuman-GEM MAR12488
H+[r] + NADPH[r] + O2[r] + AM1c (cyclosporine)[r] = H2O[r] + NADP+[r] + AM1c9 (cyclosporine)[r]
Left to rightBalancedHuman-GEM MAR12489
ATP[c] + H2O[c] + AM1c9 (cyclosporine)[c] = ADP[c] + H+[c] + Pi[c] + AM1c9 (cyclosporine)[e]
Left to rightBalancedTransportHuman-GEM MAR12490
AM1c9 (cyclosporine)[c] = AM1c9 (cyclosporine)[e]
ReversibleBalancedTransportHuman-GEM MAR12491
H+[r] + NADPH[r] + O2[r] + cyclosporine[r] = H2O[r] + NADP+[r] + AM1c (cyclosporine)[r]
Left to rightBalancedHuman-GEM MAR12492
ATP[c] + H2O[c] + AM1c (cyclosporine)[c] = ADP[c] + H+[c] + Pi[c] + AM1c (cyclosporine)[e]
Left to rightBalancedTransportHuman-GEM MAR12493
AM1c (cyclosporine)[c] = AM1c (cyclosporine)[e]
ReversibleBalancedTransportHuman-GEM MAR12494
UDP-glucuronate[r] + AM1c (cyclosporine)[r] = H+[r] + UDP[r] + AM1c-glucuronide (cyclosporine)[r]
Left to rightBalancedHuman-GEM MAR12495
ATP[c] + H2O[c] + AM1c-glucuronide (cyclosporine)[c] = ADP[c] + H+[c] + Pi[c] + AM1c-glucuronide (cyclosporine)[e]
Left to rightBalancedTransportHuman-GEM MAR12496
H+[r] + NADPH[r] + O2[r] + cyclosporine[r] = H2O[r] + NADP+[r] + AM1 (cyclosporine)[r]
Left to rightBalancedEC 1.14.13.-, 1.14.14.1Human-GEM MAR12497
AM1 (cyclosporine)[c] = AM1 (cyclosporine)[e]
ReversibleBalancedTransportHuman-GEM MAR12498
H+[c] + SAH[c] + AM9 (cyclosporine)[c] = SAM[c] + AM4N9 (cyclosporine)[c]
Left to rightBalancedHuman-GEM MAR12499
H+[r] + NADPH[r] + O2[r] + AM4N (cyclosporine)[r] = H2O[r] + NADP+[r] + AM4N9 (cyclosporine)[r]
Left to rightBalancedHuman-GEM MAR12500
AM4N9 (cyclosporine)[c] = AM4N9 (cyclosporine)[e]
ReversibleBalancedTransportHuman-GEM MAR12501
ATP[c] + H2O[c] + AM4N9 (cyclosporine)[c] = ADP[c] + H+[c] + Pi[c] + AM4N9 (cyclosporine)[e]
Left to rightBalancedTransportHuman-GEM MAR12502
H+[c] + SAH[c] + cyclosporine[c] = SAM[c] + AM4N (cyclosporine)[c]
Left to rightBalancedHuman-GEM MAR12503
ATP[c] + H2O[c] + AM4N (cyclosporine)[c] = ADP[c] + H+[c] + Pi[c] + AM4N (cyclosporine)[e]
Left to rightBalancedTransportHuman-GEM MAR12504
AM4N (cyclosporine)[c] = AM4N (cyclosporine)[e]
ReversibleBalancedTransportHuman-GEM MAR12505
H+[r] + NADPH[r] + O2[r] + cyclosporine[r] = H2O[r] + NADP+[r] + AM9 (cyclosporine)[r]
Left to rightBalancedEC 1.14.13.-, 1.14.14.1Human-GEM MAR12506
ATP[c] + H2O[c] + AM9 (cyclosporine)[c] = ADP[c] + H+[c] + Pi[c] + AM9 (cyclosporine)[e]
Left to rightBalancedTransportHuman-GEM MAR12507