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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

19,801–19,850 of 31,435, by identifier

dTDP-4-amino-4,6-dideoxy-alpha-D-glucose + AH2 + S-adenosyl-L-methionine = dTDP-3-dehydro-4,6-dideoxy-alpha-D-glucose + 5'-deoxyadenosine + L-methionine + A + NH4(+) + H(+)
Direction not assertedBalancedRhea 39647
6-oxocyclohex-1-ene-1-carbonyl-CoA + 2 H2O = 3-hydroxy-6-carboxyhexanoyl-CoA + H(+)
Direction not assertedBalancedRhea 39651
(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + AH2 + O2 = (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + A + 2 H2O
Direction not assertedBalancedRhea 39655
a 3-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,3-diacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine
Direction not assertedBalance undeterminableRhea 39659
oxidized coenzyme F420-(gamma-L-Glu)(n) + a quinol + H(+) = reduced coenzyme F420-(gamma-L-Glu)(n) + a quinone
Direction not assertedBalance undeterminableRhea 39663
a secondary alcohol + oxidized coenzyme F420-(gamma-L-Glu)(n) + H(+) = a ketone + reduced coenzyme F420-(gamma-L-Glu)(n)
Direction not asserted

?

Balance undeterminable

Rhea 39667

(9Z)-hexadecenoyl-CoA + AH2 + O2 = (9Z,12Z)-hexadecadienoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 39671

(9Z)-hexadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z)-octadecenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 39675

(11Z)-octadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(13Z)-eicosenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 39679

3-oxo-(11Z)-octadecenoyl-CoA + NADPH + H(+) = (R)-3-hydroxy-(11Z)-octadecenoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39683

(R)-3-hydroxy-(11Z)-octadecenoyl-CoA = (2E,11Z)-octadecadienoyl-CoA + H2O

Direction not assertedBalancedRhea 39687

(2E,11Z)-octadecadienoyl-CoA + NADPH + H(+) = (11Z)-octadecenoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39691

3-oxo-(13Z)-eicosenoyl-CoA + NADPH + H(+) = (R)-3-hydroxy-(13Z)-eicosenoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39695

(R)-3-hydroxy-(13Z)-eicosenoyl-CoA = (2E,13Z)-eicosadienoyl-CoA + H2O

Direction not assertedBalancedRhea 39699

(2E,13Z)-eicosadienoyl-CoA + NADPH + H(+) = (13Z)-eicosenoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39703

a long-chain fatty acyl-CoA(out) = a long-chain fatty acyl-CoA(in)

Direction not assertedBalance undeterminableTransportRhea 39707

2 reduced coenzyme F420-(gamma-L-Glu)(n) + O2 = 2 oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 39711

(9Z,12Z,15Z,18Z)-tetracosatetraenoyl-CoA + AH2 + O2 = (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + A + 2 H2O

Direction not assertedBalancedRhea 39715

tetracosanoate + reduced [NADPH--hemoprotein reductase] + O2 = 24-hydroxytetracosanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 39719

a 1,2-diacyl-sn-glycerol(in) = a 1,2-diacyl-sn-glycerol(out)

Left to rightBalance undeterminableTransportRhea 39723

a sphingomyelin(in) = a sphingomyelin(out)

Left to rightBalance undeterminableTransportRhea 39727

3-hydroxyhexadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 3,16-dihydroxyhexadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 39731

3-hydroxyoctadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 3,18-dihydroxyoctadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 39735

3-hydroxydodecanoate + NADPH + O2 + H(+) = 3,12-dihydroxydodecanoate + NADP(+) + H2O

Direction not assertedBalancedRhea 39739

a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out)

Left to rightBalance undeterminableTransportRhea 39743

cholesterol(in) = cholesterol(out)

Left to rightBalancedTransportRhea 39747

dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 11-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 39751

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 39755

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 39759

20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 39767

20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (5Z,8Z,11Z,14Z)-eicosatetraenedioate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 39771

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 17,18-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 39775

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = (17R,18S)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 39779

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = (17S,18R)-epoxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 39783

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 39787

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + reduced [NADPH--hemoprotein reductase] + O2 = 20-hydroxy-(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 39791

7beta-hydroxycholesterol(in) + ATP + H2O = 7beta-hydroxycholesterol(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 39795

20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + NAD(+) = 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + NADH + H(+)

Left to rightBalancedRhea 39799

20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate + NAD(+) + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenedioate + NADH + 2 H(+)

Left to rightBalancedRhea 39803

octadecanoate(in) = octadecanoate(out)

Direction not assertedBalancedTransportRhea 39807

(5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 18-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 39811

octadecanoate + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (R)-2-hydroxyoctadecanoate + 2 Fe(III)-[cytochrome b5] + H2O

Left to rightBalance undeterminableRhea 39815

docosanoate + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 2-hydroxydocosanoate + 2 Fe(III)-[cytochrome b5] + H2O

Left to rightBalance undeterminableRhea 39819

eicosanoate + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = 2-hydroxyeicosanoate + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 39823

1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + H2O = 1-(9Z-octadecenoyl)-sn-glycerol + phosphate

Left to rightBalancedRhea 39835

a 2,3-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol + CoA

Direction not assertedBalance undeterminableRhea 39839

a 1,3-diacyl-sn-glycerol + an acyl-CoA = a triacyl-sn-glycerol + CoA

Direction not assertedBalance undeterminableRhea 39843

a 2-acylglycerol + ATP = a 2-acyl-sn-glycerol 3-phosphate + ADP + H(+)

Left to rightBalance undeterminableRhea 39847

2 a 1-acyl-sn-glycerol = glycerol + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 39851

a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + glycerol

Direction not assertedBalance undeterminableRhea 39855

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