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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

19,651–19,700 of 31,435, by identifier

26-oxohexacosanoate + reduced [NADPH--hemoprotein reductase] + O2 = hexacosanedioate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)
Left to rightBalance undeterminableRhea 39047
cholesterol(in) + ATP + H2O = cholesterol(out) + ADP + phosphate + H(+)
Left to rightBalancedTransportRhea 39051
22-hydroxydocosanoate + reduced [NADPH--hemoprotein reductase] + O2 = 22-oxodocosanoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Left to rightBalance undeterminableRhea 39055
26-hydroxyhexacosanoate + reduced [NADPH--hemoprotein reductase] + O2 = 26-oxohexacosanoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Left to rightBalance undeterminableRhea 39059
scyllo-inositol + NADP(+) = scyllo-inosose + NADPH + H(+)
Direction not assertedBalancedRhea 39063
3-oxooctanedioyl-CoA + CoA = hexanedioyl-CoA + acetyl-CoA
Direction not assertedBalancedRhea

39067

dodecanedioyl-CoA + O2 = (2E)-dodecenedioyl-CoA + H2O2

Direction not assertedBalancedRhea 39071

(2E)-dodecenedioyl-CoA + H2O = (3S)-hydroxydodecanedioyl-CoA

Direction not assertedBalancedRhea 39075

(3S)-hydroxydodecanedioyl-CoA + NAD(+) = 3-oxododecanedioyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 39079

3-oxododecanedioyl-CoA + CoA = decanedioyl-CoA + acetyl-CoA

Direction not assertedBalancedRhea 39083

decanedioyl-CoA + O2 = (2E)-decenedioyl-CoA + H2O2

Direction not assertedBalancedRhea 39087

(2E)-decenedioyl-CoA + H2O = (3S)-hydroxydecanedioyl-CoA

Direction not assertedBalancedRhea 39091

(3S)-hydroxydecanedioyl-CoA + NAD(+) = 3-oxodecanedioyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 39095

3-oxodecanedioyl-CoA + CoA = octanedioyl-CoA + acetyl-CoA

Direction not assertedBalancedRhea 39099

sitosterol(in) + ATP + H2O = sitosterol(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 39103

(5S)-hydroperoxy-(18S)-hydroxy-(6E,8Z,11Z,14Z,16E)-eicosapentaenoate = (5S,6S)-epoxy-(18S)-hydroxy-(7E,9E,11Z,14Z,16E)-eicosapentaenoate + H2O

Left to rightBalancedRhea 39107

4-hydroxy-2,5-dimethyl-furan-3(2H)-one + NADP(+) = 4-hydroxy-5-methyl-2-methylenefuran-3(2H)-one + NADPH + H(+)

Direction not assertedBalancedRhea 39111

4-hydroxy-2,5-dimethyl-furan-3(2H)-one + NAD(+) = 4-hydroxy-5-methyl-2-methylenefuran-3(2H)-one + NADH + H(+)

Direction not assertedBalancedRhea 39115

(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O2

Left to rightBalancedRhea 39119

(2E,6Z,9Z,12Z,15Z,18Z,21Z)-tetracosaheptaenoyl-CoA + H2O = (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA

Direction not assertedBalancedRhea 39123

(S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NAD(+) = 3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 39127

3-oxo-(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoA + CoA = (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 39131

(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + O2 = (2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O2

Left to rightBalancedRhea 39135

(2E,6Z,9Z,12Z,15Z,18Z)-tetracosahexaenoyl-CoA + H2O = (S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA

Direction not assertedBalancedRhea 39139

(S)-3-hydroxy-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NAD(+) = 3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 39143

3-oxo-(6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoyl-CoA + CoA = (4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 39147

3-oxooctadecanoyl-CoA + NADPH + H(+) = (3R)-hydroxyoctadecanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39151

(3R)-hydroxyoctadecanoyl-CoA = (2E)-octadecenoyl-CoA + H2O

Left to rightBalancedRhea 39155

(3R)-hydroxyhexadecanoyl-CoA = (2E)-hexadecenoyl-CoA + H2O

ReversibleBalancedRhea 39159

3-oxohexadecanoyl-CoA + NADPH + H(+) = (3R)-hydroxyhexadecanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39163

tetradecanoyl-CoA + malonyl-CoA + H(+) = 3-oxohexadecanoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 39167

3-oxoeicosanoyl-CoA + NADPH + H(+) = (3R)-hydroxyeicosanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39171

(3R)-hydroxyeicosanoyl-CoA = (2E)-eicosenoyl-CoA + H2O

Left to rightBalancedRhea 39175

(2E)-eicosenoyl-CoA + NADPH + H(+) = eicosanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39179

3-oxodocosanoyl-CoA + NADPH + H(+) = (3R)-hydroxydocosanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39183

(3R)-hydroxydocosanoyl-CoA = (2E)-docosenoyl-CoA + H2O

Left to rightBalancedRhea 39187

(2E)-docosenoyl-CoA + NADPH + H(+) = docosanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39191

3-oxotetracosanoyl-CoA + NADPH + H(+) = (3R)-hydroxytetracosanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39195

(3R)-hydroxytetracosanoyl-CoA = (2E)-tetracosenoyl-CoA + H2O

Left to rightBalancedRhea 39199

(2E)-tetracosenoyl-CoA + NADPH + H(+) = tetracosanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39203

3-oxohexacosanoyl-CoA + NADPH + H(+) = (3R)-hydroxyhexacosanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39207

(3R)-hydroxyhexacosanoyl-CoA = (2E)-hexacosenoyl-CoA + H2O

ReversibleBalancedRhea 39211

(2E)-hexacosenoyl-CoA + NADPH + H(+) = hexacosanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39215

3-oxooctacosanyol-CoA + NADPH + H(+) = (3R)-hydroxyoctacosanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39219

(3R)-hydroxyoctacosanoyl-CoA = (2E)-octacosenoyl-CoA + H2O

Right to leftBalancedRhea 39223

(2E)-octacosenoyl-CoA + NADPH + H(+) = octacosanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39227

3-oxo-triacontanoyl-CoA + NADPH + H(+) = (3R)-hydroxytriacontanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39231

(3R)-hydroxytriacontanoyl-CoA = (2E)-triacontenoyl-CoA + H2O

Right to leftBalancedRhea 39235

(2E)-triacontenoyl-CoA + NADPH + H(+) = triacontanoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39239

3-oxo-(11Z)-eicosenoyl-CoA + NADPH + H(+) = (3R)-hydroxy-(11Z)-eicosenoyl-CoA + NADP(+)

Direction not assertedBalancedRhea 39243

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