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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

19,351–19,400 of 31,435, by identifier

(S)-(2,4-dichlorophenoxy)propanoate + 2-oxoglutarate + O2 = 2,4-dichlorophenol + pyruvate + succinate + CO2
Direction not assertedBalancedRhea 37827
(S)-2-(4-chloro-2-methylphenoxy)propanoate + 2-oxoglutarate + O2 = 2-methyl-4-chlorophenol + pyruvate + succinate + CO2
Direction not assertedBalancedRhea 37831
aklavinone + NADPH + O2 + H(+) = epsilon-rhodomycinone + NADP(+) + H2O
Direction not assertedBalancedRhea 37835
1-O-octadecyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-O-octadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Left to rightBalancedRhea 37839
1-eicosanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-eicosanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Left to rightBalancedRhea 37843
13-dihydrodaunorubicin + NADPH + O2 + H(+) = daunorubicin + NADP(+) + 2 H2O
Direction not assertedBalancedRhea 37847

13-deoxydaunorubicin + NADPH + O2 + H(+) = 13-dihydrodaunorubicin + NADP(+) + H2O

Direction not assertedBalancedRhea 37851

hexanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-hexanoyl-sn-glycero-3-phosphocholine + CoA

Left to rightBalancedRhea 37855

octanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + CoA

Left to rightBalancedRhea 37859

decanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-decanoyl-sn-glycero-3-phosphocholine + CoA

Left to rightBalancedRhea 37863

tetradecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + CoA

Left to rightBalancedRhea 37867

2-heptyl-4(1H)-quinolone + NADH + O2 + H(+) = 2-heptyl-3-hydroxy-4(1H)-quinolone + NAD(+) + H2O

Direction not assertedBalancedRhea 37871

aklanonate + S-adenosyl-L-methionine = methyl aklanonate + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 37875

methyl aklanonate = aklaviketone

Direction not assertedBalancedRhea 37879

oxalate + acetyl-CoA = oxalyl-CoA + acetate

Direction not assertedBalancedRhea 37883

small RNA 3'-end nucleotide + S-adenosyl-L-methionine = small RNA 3'-end 2'-O-methylnucleotide + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 37887

aclacinomycin T + H2O = 15-demethylaclacinomycin T + methanol

Direction not assertedBalancedRhea 37891

protodioscin + H2O = 26-deglucoprotodioscin + D-glucose

Direction not assertedBalancedRhea 37895

7-[(3S)-3-amino-3-carboxypropyl]wyosine(37) in tRNA(Phe) + 2-oxoglutarate + O2 = 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine(37) in tRNA(Phe) + succinate + CO2

Left to rightBalance undeterminableRhea 37899

6-hydroxytryprostatin B + S-adenosyl-L-methionine = tryprostatin A + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 37903

(9Z)-octadecenoate + O2 = (8E,10S)-10-hydroperoxy-octadeca-8-enoate

Direction not assertedBalancedRhea 37907

2-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycerol + CoA

Left to rightBalancedRhea 37911

1-(9Z-octadecenoyl)-glycerol + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-glycerol + CoA

Left to rightBalancedRhea 37915

(9Z,12Z)-octadecadienoate + O2 = (8E,10S,12Z)-10-hydroperoxyoctadeca-8,12-dienoate

Direction not assertedBalancedRhea 37919

(9Z,12Z,15Z)-octadecatrienoate + O2 = (8E,10S,12Z,15Z)-10-hydroperoxyoctadeca-8,12,15-trienoate

Direction not assertedBalancedRhea 37923

(8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate = 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O

Left to rightBalancedRhea 37927

(8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate = (10R)-hydroxy-(8S,9S)-epoxy-(5Z,11Z,14Z)-eicosatrienoate

Left to rightBalancedRhea 37931

(8R)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoate = 8-oxo-(5Z,9E,11Z,14Z)-eicosatetraenoate + H2O

Left to rightBalancedRhea 37935

(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate = (8R)-hydroxy-(11R,12R)-epoxy-(5Z,9E,14Z)-eicosatrienoate

Left to rightBalancedRhea 37939

(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate = 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate + H2O

Left to rightBalancedRhea 37943

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate = 12-oxo-(5Z,8Z,10E,14Z)-eicosatetraenoate + H2O

Left to rightBalancedRhea 37947

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate = (10R)-hydroxy-(11S,12S)-epoxy-(5Z,8Z,14Z)-eicosatrienoate

Left to rightBalancedRhea 37951

(12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate = (8R)-hydroxy-(11S,12S)-epoxy-(5Z,9E,14Z)-eicosatrienoate

Left to rightBalancedRhea 37955

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate = (13R)-hydroxy-(14S,15S)-epoxy-(5Z,8Z,11Z)-eicosatrienoate

Left to rightBalancedRhea 37959

galactitol + NAD(+) = D-galactose + NADH + H(+)

Direction not assertedBalancedRhea 37963

galactitol + NADP(+) = D-galactose + NADPH + H(+)

Direction not assertedBalancedRhea 37967

octadecanoyl-CoA + NADPH + O2 + H(+) = (9Z)-octadecenoyl-CoA + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 37971

phytyl diphosphate + homogentisate + H(+) = 2-methyl-6-phytyl-1,4-benzene-1,4-diol + CO2 + diphosphate

Direction not assertedBalancedRhea 37975

2-methyl-6-phytyl-1,4-benzene-1,4-diol + S-adenosyl-L-methionine = 2,3-dimethyl-6-phytylbenzene-1,4-diol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 37979

gamma-tocopherol = 2,3-dimethyl-6-phytylbenzene-1,4-diol

Direction not assertedBalancedRhea 37983

delta-tocopherol = 2-methyl-6-phytyl-1,4-benzene-1,4-diol

Direction not assertedBalancedRhea 37987

delta-tocopherol + S-adenosyl-L-methionine = beta-tocopherol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 37991

all-trans-nonaprenyl diphosphate + homogentisate + H(+) = 2-methyl-6-(all-trans-nonaprenyl)benzene-1,4-diol + CO2 + diphosphate

Direction not assertedBalancedRhea 37995

2-methyl-6-(all-trans-nonaprenyl)benzene-1,4-diol + S-adenosyl-L-methionine = plastoquinol-9 + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 37999

homogentisate + (2E,6E,10E)-geranylgeranyl diphosphate + H(+) = 6-geranylgeranyl-2-methylbenzene-1,4-diol + CO2 + diphosphate

Direction not assertedBalancedRhea 38003

6-geranylgeranyl-2-methylbenzene-1,4-diol + S-adenosyl-L-methionine = 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 38007

chlorophyll a + H2O = phytol + chlorophyllide a + H(+)

Direction not assertedBalancedRhea 38011

delta-tocotrienol = 6-geranylgeranyl-2-methylbenzene-1,4-diol

Direction not assertedBalancedRhea 38015

1-decanoylglycerol + (9Z)-octadecenoyl-CoA = 1-decanoyl-2-(9Z-octadecenoyl)-glycerol + CoA

Left to rightBalancedRhea 38019

gamma-tocotrienol = 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diol

Direction not assertedBalancedRhea 38023

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