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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

19,201–19,250 of 31,435, by identifier

2',3'-cyclophospho-GMP + H2O = guanosine 2'-phosphate + H(+)
Direction not assertedBalancedRhea 37211
D-valine + A + H2O = 3-methyl-2-oxobutanoate + AH2 + NH4(+)
Direction not assertedBalancedRhea 37219
1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA
Left to rightBalancedRhea 37223
(E,E)-sorbate + H(+) = (E)-1,3-pentadiene + CO2
Direction not assertedBalancedRhea 37227
L-alaninamide + H2O = L-alanine + NH4(+)
Direction not assertedBalancedRhea 37231
2',3'-cyclophospho-UMP + H2O = uridine 2'-phosphate + H(+)
Direction not assertedBalancedRhea 37239
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 37243

thymidine 3'-phosphate + H2O = thymidine + phosphate

Direction not assertedBalancedRhea 37247

cysteamine S-phosphate + H2O = cysteamine + phosphate

Direction not assertedBalancedRhea 37251

D-asparagine + A + H2O = 2-oxosuccinamate + AH2 + NH4(+)

Direction not assertedBalancedRhea 37255

(2S)-2-aminobutanoate + NAD(+) + H2O = 2-oxobutanoate + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 37259

L-alanyl-L-aspartate(out) + ATP + H2O = L-alanyl-L-aspartate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 37263

L-alanyl-L-aspartate + H2O = L-aspartate + L-alanine

Direction not assertedBalancedRhea 37267

L-alanyl-L-glutamine(out) + ATP + H2O = L-alanyl-L-glutamine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 37271

L-alanyl-L-glutamine + H2O = L-glutamine + L-alanine

Direction not assertedBalancedRhea 37275

L-alanyl-L-histidine(out) + ATP + H2O = L-alanyl-L-histidine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 37279

L-alanyl-L-histidine + H2O = L-histidine + L-alanine

Left to rightBalancedRhea 37283

L-alanyl-L-leucine(out) + ATP + H2O = L-alanyl-L-leucine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 37287

L-alanyl-L-leucine + H2O = L-leucine + L-alanine

Direction not assertedBalancedRhea 37291

L-alanyl-L-threonine(out) + ATP + H2O = L-alanyl-L-threonine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 37295

L-alanyl-L-threonine + H2O = L-threonine + L-alanine

Direction not assertedBalancedRhea 37299

glycyl-L-asparagine(out) + ATP + H2O = glycyl-L-asparagine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 37303

glycyl-L-asparagine + H2O = L-asparagine + glycine

Direction not assertedBalancedRhea 37307

glycyl-L-glutamine(out) + ATP + H2O = glycyl-L-glutamine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 37311

glycyl-L-glutamine + H2O = L-glutamine + glycine

Direction not assertedBalancedRhea 37315

glycyl-L-methionine(out) + ATP + H2O = glycyl-L-methionine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 37319

glycyl-L-methionine + H2O = L-methionine + glycine

Direction not assertedBalancedRhea 37323

L-methionyl-L-alanine(out) + ATP + H2O = L-methionyl-L-alanine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 37327

L-methionyl-L-alanine + H2O = L-methionine + L-alanine

Direction not assertedBalancedRhea 37331

5,6-dihydrothymine + H2O = 3-(carbamoylamino)-2-methylpropanoate + H(+)

Direction not assertedBalancedRhea 37335

3-(carbamoylamino)-2-methylpropanoate + H2O + 2 H(+) = (R)-3-amino-2-methylpropanoate + NH4(+) + CO2

Left to rightBalancedRhea 37339

adenosine 2'-phosphate + H2O = adenosine + phosphate

Left to rightBalancedRhea 37343

(R)-lactate + D-alanine + ATP = D-alanyl-(R)-lactate + ADP + phosphate

Direction not assertedBalancedRhea 37347

cytidine 2'-phosphate + H2O = cytidine + phosphate

Direction not assertedBalancedRhea 37351

uridine 2'-phosphate + H2O = uridine + phosphate

Direction not assertedBalancedRhea 37355

D-glucosamine(out) + N(pros)-phospho-L-histidyl-[protein] = D-glucosamine 6-phosphate(in) + L-histidyl-[protein]

Direction not assertedBalance undeterminableRhea 37359

heme b + 5 AH2 + 4 O2 + 2 H(+) = beta-staphylobilin + Fe(2+) + formaldehyde + 5 A + 4 H2O

Direction not assertedBalancedRhea 37363

CDP-2,3-bis-O-(phytanyl)-sn-glycerol + L-serine = 2,3-bis-O-phytanyl-sn-glycero-3-phospho-L-serine + CMP + H(+)

Direction not assertedBalancedRhea 37367

a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-(purine-ribonucleoside) in mRNA + H2O = a 5'-end phospho (purine-ribonucleoside) in mRNA + N(7)-methyl-GDP + 2 H(+)

Direction not assertedBalance undeterminableRhea 37371

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serine + CoA

Left to rightBalancedRhea 37375

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-L-serine + CoA

Left to rightBalancedRhea 37379

1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA

Left to rightBalancedRhea 37383

1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA

Left to rightBalancedRhea 37387

1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA

Left to rightBalancedRhea 37391

1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z)-octadecenoyl-2-(5Z,8Z,11Z,14Z)-icosatetraenoyl-sn-glycero-3-phosphocholine + CoA

Left to rightBalancedRhea 37395

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-hexadecenoyl-CoA = 1-(9Z-octadecenoyl)-2-(9Z-hexadecenoyl)-sn-glycero-3-phospho-L-serine + CoA

Left to rightBalancedRhea 37399

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + octadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phospho-L-serine + CoA

Left to rightBalancedRhea 37403

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + CoA

Left to rightBalancedRhea 37407

aklavinone + NADP(+) = aklaviketone + NADPH + 2 H(+)

Direction not assertedBalancedRhea 37411

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphoserine + CoA

Left to rightBalancedRhea 37415

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