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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

19,001–19,050 of 31,435, by identifier

5alpha-cholest-8-en-3beta-ol + NADP(+) = zymosterol + NADPH + H(+)
Right to leftBalancedRhea 36399
a cholesterol ester + H2O = cholesterol + a fatty acid + H(+)
Left to rightBalance undeterminableRhea 36403
L-threonine + hydrogencarbonate + ATP = L-threonylcarbamoyladenylate + diphosphate + H2O
Direction not assertedBalancedRhea 36407
7-dehydrocholesterol + hnu = calciol
Direction not assertedBalance undeterminableRhea 36411
2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + 3 S-adenosyl-L-methionine = diphthine-[translation elongation factor 2] + 3 S-adenosyl-L-homocysteine + 3 H(+)
Direction not assertedBalance undeterminableRhea 36415
2-[(3S)-amino-3-carboxypropyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-3-carboxy-3-(methylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H(+)
Direction not asserted

Balance undeterminable

Rhea 36419

2-[(3S)-3-carboxy-3-(methylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = 2-[(3S)-3-carboxy-3-(dimethylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 36423

2-[(3S)-3-carboxy-3-(dimethylamino)propyl]-L-histidyl-[translation elongation factor 2] + S-adenosyl-L-methionine = diphthine-[translation elongation factor 2] + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 36427

a purine 2'-deoxy-D-ribonucleoside + phosphate = a purine nucleobase + 2-deoxy-alpha-D-ribose 1-phosphate

Direction not assertedBalance undeterminableRhea 36431

a 1,2-diacyl-sn-glycero-3-phosphate(in) = a 1,2-diacyl-sn-glycero-3-phosphate(out)

Left to rightBalance undeterminableTransportRhea 36435

a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(in) + ATP + H2O = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine(out) + ADP + phosphate + H(+)

Left to rightBalance undeterminableTransportRhea 36439

dihydrochanoclavine-I aldehyde = 6,8-dimethyl-6,7-didehydroergoline + H2O

Direction not assertedBalancedRhea 36443

glycyl-L-proline(out) + ATP + H2O = glycyl-L-proline(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 36447

glycyl-L-glutamate(out) + ATP + H2O = glycyl-L-glutamate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 36451

L-alanylglycine(out) + ATP + H2O = L-alanylglycine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 36455

glycyl-L-proline + H2O = L-proline + glycine

Direction not assertedBalancedRhea 36459

glycyl-L-glutamate + H2O = glycine + L-glutamate

Direction not assertedBalancedRhea 36463

L-alanylglycine + H2O = L-alanine + glycine

Direction not assertedBalancedRhea 36467

3,4,5-trihydroxybenzoate(out) + H(+)(out) = 3,4,5-trihydroxybenzoate(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 36471

(5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + malonyl-CoA + H(+) = (7Z,10Z,13Z,16Z)-3-oxodocosatetraenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36475

(7Z,10Z,13Z,16Z)-docosatetraenoyl-CoA + malonyl-CoA + H(+) = (9Z,12Z,15Z,18Z)-3-oxotetracosatetraenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36479

(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36483

S-adenosyl 3-(methylsulfanyl)propylamine + agmatine = N(1)-(3-aminopropyl)agmatine + S-methyl-5'-thioadenosine + H(+)

Direction not assertedBalancedRhea 36487

(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA + malonyl-CoA + H(+) = (9Z,12Z,15Z,18Z,21Z)-3-oxotetracosapentaenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36491

alpha-D-glucose + ATP = alpha-D-glucose 6-phosphate + ADP + H(+)

Direction not assertedBalancedRhea 36495

2-dehydro-3-deoxy-L-rhamnonate + NAD(+) = 2,4-didehydro-3-deoxy-L-rhamnonate + NADH + H(+)

Direction not assertedBalancedRhea 36499

(9Z,12Z)-octadecadienoyl-CoA + malonyl-CoA + H(+) = (11Z,14Z)-3-oxoicosa-11,14-dienoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36503

docosanoyl-CoA + malonyl-CoA + H(+) = 3-oxotetracosanoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36507

(9Z)-octadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z)-eicosenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36511

tetracosanoyl-CoA + malonyl-CoA + H(+) = 3-oxohexacosanoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36515

hexacosanoyl-CoA + malonyl-CoA + H(+) = 3-oxooctacosanyol-CoA + CO2 + CoA

Left to rightBalancedRhea 36519

(9Z,12Z,15Z)-octadecatrienoyl-CoA + malonyl-CoA + H(+) = (11Z,14Z,17Z)-3-oxoeicosatrienoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36523

(11Z)-eicosenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(13Z)-docosenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36527

(13Z)-docosenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(15Z)-tetracosenoyl-CoA + CO2 + CoA

Left to rightBalancedRhea 36531

docosanoyl-CoA + sphinganine = N-docosanoylsphinganine + CoA + H(+)

Left to rightBalancedRhea 36535

sphinganine + hexadecanoyl-CoA = N-hexadecanoylsphinganine + CoA + H(+)

Left to rightBalancedRhea 36539

mycothiol S-conjugate + H2O = an N-acetyl-L-cysteine-S-conjugate + 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside

Direction not assertedBalance undeterminableRhea 36543

sphinganine + octadecanoyl-CoA = N-(octadecanoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36547

3-O-[beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CDP-L-ribitol = 3-O-[Rib-ol-P-3-beta-D-GalNAc-(1->3)-beta-D-GlcNAc-(1->4)-(O-6-P-alpha-D-Man)]-Thr-[protein] + CMP + H(+)

Left to rightBalance undeterminableRhea 36551

eicosanoyl-CoA + sphinganine = N-eicosanoylsphinganine + CoA + H(+)

Left to rightBalancedRhea 36555

cis-4-hydroxy-D-proline + A = 4-hydroxy-1-pyrroline-2-carboxylate + AH2 + H(+)

Direction not assertedBalancedRhea 36559

GDP-beta-L-colitose + NADP(+) = GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADPH + H(+)

Direction not assertedBalancedRhea 36563

GDP-beta-L-colitose + NAD(+) = GDP-4-dehydro-3,6-dideoxy-alpha-D-mannose + NADH + H(+)

Direction not assertedBalancedRhea 36567

sphinganine + tetradecanoyl-CoA = N-(tetradecanoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36571

sphinganine + (9Z)-octadecenoyl-CoA = N-(9Z-octadecenoyl)-sphinganine + CoA + H(+)

Left to rightBalancedRhea 36575

dTDP-alpha-D-fucose + NAD(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADH + H(+)

Direction not assertedBalancedRhea 36579

dTDP-alpha-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADPH + H(+)

Direction not assertedBalancedRhea 36583

an aldopyranose + NADP(+) = aldono-1,5-lactone + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 36587

(S)-2-chloropropanoate + NADP(+) = 2-chloroacrylate + NADPH + H(+)

Direction not assertedBalancedRhea 36591

hydrogen sulfide + NADP(+) = sulfur + NADPH

Direction not assertedBalancedRhea 36595

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