Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

18,501–18,550 of 18,558 reactions from Rhea

tricarballylate + FAD + H(+) = cis-aconitate + FADH2
Direction not assertedBalancedRhea 86635
a quinone + FADH2 = a quinol + FAD + H(+)
Direction not assertedBalance undeterminableRhea 86659
tricarballylate(out) + H(+)(out) = tricarballylate(in) + H(+)(in)
Direction not assertedBalancedTransportRhea 86667
N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein] + glutaryl-CoA = N(6)-[(R)-S(8)-glutaryldihydrolipoyl]-L-lysyl-[protein] + CoA
Direction not assertedBalance undeterminableRhea 86675
nicotinamide(out) = nicotinamide(in)
Direction not assertedBalancedTransportRhea 86679
beta-citrylglutamate + H2O = citrate + L-glutamate
Direction not assertedBalancedRhea 86691
(S)-lactate + ATP + CoA = (S)-lactoyl-CoA + AMP + diphosphate

Left to rightBalancedRhea 86695

isopentadecanoyl-CoA + O2 = (2E)-13-methyltetradecenoyl-CoA + H2O2

Left to rightBalancedRhea 86699

L-leucine(out) + L-glutamine(in) = L-leucine(in) + L-glutamine(out)

Direction not assertedBalancedTransportRhea 86703

L-tyrosine(out) + L-phenylalanine(in) = L-tyrosine(in) + L-phenylalanine(out)

Direction not assertedBalancedTransportRhea 86707

acetoacetyl-CoA + (S)-lactate = (S)-lactoyl-CoA + acetoacetate

Direction not assertedBalancedRhea 86711

2,4-dichlorophenol + AH2 = 4-chlorophenol + chloride + A + H(+)

Direction not assertedBalancedRhea 86719

L-tyrosine(out) + L-leucine(in) = L-tyrosine(in) + L-leucine(out)

Direction not assertedBalancedTransportRhea 86723

L-dopa(out) + L-leucine(in) = L-dopa(in) + L-leucine(out)

Direction not assertedBalancedTransportRhea 86727

3-O-methyl-L-dopa(out) + L-leucine(in) = 3-O-methyl-L-dopa(in) + L-leucine(out)

Direction not assertedBalancedTransportRhea 86731

3,3',5-triiodo-L-thyronine(out) + L-leucine(in) = 3,3',5-triiodo-L-thyronine(in) + L-leucine(out)

Direction not assertedBalancedTransportRhea 86743

L-thyroxine(out) + L-leucine(in) = L-thyroxine(in) + L-leucine(out)

Direction not assertedBalancedTransportRhea 86747

UDP-beta-L-threo-pentopyranos-4-ulose + NADH + H(+) = UDP-alpha-D-xylose + NAD(+)

Direction not assertedBalancedRhea 86751

N-acetyl-S-benzyl-L-cysteine + H2O = S-benzyl-L-cysteine + acetate

Direction not assertedBalancedRhea 86755

N(alpha)-acetyl-L-histidine + H2O = L-histidine + acetate

Direction not assertedBalancedRhea 86759

N-acetyl-L-tryptophan + H2O = L-tryptophan + acetate

Direction not assertedBalancedRhea 86767

tetradecanoyl-CoA + 2 NADH + 2 H(+) = tetradecan-1-ol + 2 NAD(+) + CoA

Direction not assertedBalancedRhea 86771

hexadecanoyl-CoA + 2 NADH + 2 H(+) = hexadecan-1-ol + 2 NAD(+) + CoA

Direction not assertedBalancedRhea 86775

CDP-ethanolamine + H2O = phosphoethanolamine + CMP + 2 H(+)

Direction not assertedBalancedRhea 86791

2-aminomuconate 6-semialdehyde = picolinate + H2O + H(+)

Direction not assertedBalancedRhea 86795

cyclic ADP-beta-D-ribose + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + 2 H(+)

Direction not assertedBalancedRhea 86799

3-sulfinopropanoate + ATP + CoA = 3-sulfinopropanoyl-CoA + ADP + phosphate

Direction not assertedBalancedRhea 86803

adenosine 5'-phosphosulfate + ATP = P(1),P(4)-bis(5'-adenosyl) tetraphosphate + sulfate

Direction not assertedBalancedRhea 86819

N-(4-ethoxyphenyl)acetamide + reduced [NADPH--hemoprotein reductase] + O2 = 4-acetamidophenol + acetaldehyde + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 86823

testosterone 17-sulfate(in) + ATP + H2O = testosterone 17-sulfate(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 86827

androsterone 3alpha-sulfate(in) + ATP + H2O = androsterone 3alpha-sulfate(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 86831

3beta-androst-5-en-17-one 3-O-(beta-D-glucuronate)(in) + ATP + H2O = 3beta-androst-5-en-17-one 3-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 86835

epitestosterone 17-O-(beta-D-glucuronate)(in) + ATP + H2O = epitestosterone 17-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 86839

3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)(in) + ATP + H2O = 3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 86843

testosterone 17-O-(beta-D-glucuronate)(in) + ATP + H2O = testosterone 17-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 86847

estrone 3-O-(beta-D-glucuronate)(in) + ATP + H2O = estrone 3-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 86851

17beta-estradiol 3-O-(beta-D-glucuronate)(in) + ATP + H2O = 17beta-estradiol 3-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 86855

16alpha,17beta-estriol 3-O-(beta-D-glucuronate)(in) + ATP + H2O = 16alpha,17beta-estriol 3-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 86859

16alpha,17beta-estriol 16-O-(beta-D-glucuronate)(in) + ATP + H2O = 16alpha,17beta-estriol 16-O-(beta-D-glucuronate)(out) + ADP + phosphate + H(+)

Left to rightBalancedTransportRhea 86863

hydrogen cyanide + 2 H2O = formate + NH4(+)

Direction not assertedBalancedRhea 86867

3,7,11,15-tetramethylhexadecanoate(in) + ATP + H2O = 3,7,11,15-tetramethylhexadecanoate(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 86875

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 86879

2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA

Direction not assertedBalancedRhea 86883

2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + CoA

Direction not assertedBalancedRhea 86887

2-hexadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 86891

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 86895

a ganglioside SM1b (d18:1(4E)) + 3'-phosphoadenylyl sulfate = a ganglioside SB1a (d18:1(4E)) + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 86899

a globoside Forssman (d18:1(4E)) + H2O = a globoside Gb4Cer (d18:1(4E)) + N-acetyl-alpha-D-galactosamine

Direction not assertedBalance undeterminableRhea 86907

a ganglioside GM3 (d18:1(4E)) + H2O = N-acetyl-alpha-neuraminosyl-(2->3)-beta-D-galactosyl-(1->4)-D-glucose + an N-acylsphing-4-enine

Direction not assertedBalance undeterminableRhea 86911

a ganglioside GM1 (d18:1(4E)) + H2O = beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-[alpha-Neu5Ac-(2->3)]-beta-D-Gal-(1->4)-D-Glc + an N-acylsphing-4-enine

Direction not assertedBalance undeterminableRhea 86915

Page 371 of 372