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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

18,401–18,450 of 18,558 reactions from Rhea

(9Z)-17-[(O-beta-D-glucosyl-(1->2)-beta-D-glucosyl)oxy]-octadecenoate-beta-D-glucosyl-(1->2)-beta-D-glucoside = (9Z)-17-[(beta-D-glucosyl-(1->2)-beta-D-glucosyl)oxy]-octadec-9-eno-1,4''-lactone + beta-sophorose
Direction not assertedBalancedRhea 86083
a steroid + reduced [NADPH--hemoprotein reductase] + O2 = a 11alpha-hydroxy steroid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 86087
testosterone + reduced [NADPH--hemoprotein reductase] + O2 = 11alpha-hydroxytestosterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 86091
androst-4-ene-3,17-dione + reduced [NADPH--hemoprotein reductase] + O2 = 11alpha-hydroxyandrost-4-ene-3,17-dione + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 86095
20beta-dihydrocortisol + NAD(+) = cortisol + NADH + H(+)
Direction not assertedBalancedRhea 86103
(11Z)-docosenoyl-CoA(4-) + O2 = (2E,11Z)-docosadienoyl-CoA + H2O2

? Direction not asserted

Balanced

Rhea 86107

5beta-pregnan-3alpha,11beta,17alpha,20beta,21-pentol + NAD(+) = tetrahydrocortisol + NADH + H(+)

Direction not assertedBalancedRhea 86111

20beta-dihydro-11-deoxycortisol + NAD(+) = 11-deoxycortisol + NADH + H(+)

Direction not assertedBalancedRhea 86115

20beta-dihydrocorticosterone + NAD(+) = corticosterone + NADH + H(+)

Direction not assertedBalancedRhea 86119

phosphite + AMP + NAD(+) = ADP + NADH + 2 H(+)

Direction not assertedBalancedRhea 86123

(9Z)-17-[(6-O-acetyl-beta-D-glucosyl-(1->2)-6-O-acetyl-beta-D-glucosyl)oxy]-octadecenoate-beta-D-glucosyl-(1->2)-beta-D-glucoside = (9Z)-17-[(6-O-acetyl-beta-D-glucosyl-(1->2)-6-O-acetyl-beta-D-glucosyl)oxy]-octadec-9-eno-1,4''-lactone + beta-sophorose

Direction not assertedBalancedRhea 86127

21-hydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + O2 = 11alpha-hydroxycorticosterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 86135

21-hydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + O2 = 6beta-hydroxy-11-deoxycorticosterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 86139

questin hydroquinone + O2 = demethylsulochrin + 2 H(+)

Direction not assertedBalancedRhea 86143

questin hydroquinone + NADP(+) = questin + NADPH + 2 H(+)

Direction not assertedBalancedRhea 86147

L-Met-L-Arg-(3-NO2)-L-Tyr-L-Leu-L-His + 4 H2O + H(+) = 3-nitro-L-tyrosine + L-histidine + L-leucine + L-arginine + L-methionine

Direction not assertedBalancedRhea 86151

(11Z)-eicosenoyl-CoA + O2 = (2E,11Z)-eicosadienoyl-CoA + H2O2

Left to rightBalancedRhea 86155

(9Z)-17-hydroxyoctadec-9-enoate 17-O-sophoroside + acetyl-CoA = (9Z)-17-[(6-O-acetyl-beta-D-glucosyl-(1->2)-beta-D-glucosyl)oxy]-octadecenoate + CoA

Direction not assertedBalancedRhea 86159

(9Z)-17-[(6-O-acetyl-beta-D-glucosyl-(1->2)-beta-D-glucosyl)oxy]-octadecenoate + acetyl-CoA = (9Z)-17-hydroxyoctadec-9-enoate 17-O-(6-O-acetyl-beta-D-glucosyl)-(1->2)-6-O-acetyl-beta-D-glucoside + CoA

Direction not assertedBalancedRhea 86163

(9Z)-octadecenoyl-CoA + O2 = (2E,9Z)-octadecadienoyl-CoA + H2O2

Left to rightBalancedRhea 86167

(3R)-hydroxy-(13Z)-docosenoyl-CoA + NAD(+) = 3-oxo-(13Z)-docosenoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 86171

(3R)-hydroxy-(15Z)-tetracosenoyl-CoA + NAD(+) = 3-oxo-(15Z)-tetracosenoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 86175

(3R)-hydroxy-(11Z)-eicosenoyl-CoA + NAD(+) = 3-oxo-(11Z)-eicosenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 86179

(3R)-hydroxy-(9Z)-octadecenoyl-CoA + NAD(+) = 3-oxo-(9Z-octadecenoyl)-CoA + NADH + H(+)

Direction not assertedBalancedRhea 86183

(3R)-hydroxy-(7Z)-hexadecenoyl-CoA + NAD(+) = 3-oxo-(7Z-hexadecenoyl)-CoA + NADH + H(+)

Direction not assertedBalancedRhea 86187

(3R)-hydroxy-(5Z)-tetradecenoyl-CoA + NAD(+) = 3-oxo-(5Z-tetradecenoyl)-CoA + NADH + H(+)

Left to rightBalancedRhea 86191

(3R)-hydroxy-(11Z)-docosenoyl-CoA + NAD(+) = 3-oxo-(11Z)-docosenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 86195

(3R)-hydroxy-(9Z)-eicosenoyl-CoA + NAD(+) = 3-oxo-(9Z)-eicosenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 86199

(3R)-hydroxy-(7Z)-octadecenoyl-CoA + NAD(+) = 3-oxo-(7Z)-octadecenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 86203

(3R)-hydroxy-(5Z)-hexadecenoyl-CoA + NAD(+) = 3-oxo-(5Z)-hexadecenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 86207

N(6)-methyladenosine + ATP = N(6)-methyl-AMP + ADP + H(+)

Left to rightBalancedRhea 86211

N(6),N(6)-dimethyladenosine + ATP = N(6),N(6)-dimethyl-AMP + ADP + H(+)

Left to rightBalancedRhea 86215

N(6)-(dimethylallyl)adenosine + ATP = N(6)-(dimethylallyl)adenosine 5'-phosphate + ADP + H(+)

Left to rightBalancedRhea 86219

N(6),N(6)-dimethyl-AMP + H2O + H(+) = dimethylamine + IMP

Left to rightBalancedRhea 86223

N(6)-(dimethylallyl)adenosine 5'-phosphate + H2O + H(+) = dimethylallylamine + IMP

Left to rightBalancedRhea 86227

NAADPH + O2 + H(+) = NAADP(+) + H2O2

Direction not assertedBalancedRhea 86235

NAADPH + 2 O2 = NAADP(+) + 2 superoxide + H(+)

Direction not assertedBalancedRhea 86239

NAADP(+) + D-glucose 6-phosphate = NAADPH + 6-phospho-D-glucono-1,5-lactone + H(+)

Direction not assertedBalancedRhea 86243

a beta-D-GlcNAc-(1->3)-beta-D-Man-(1->4)-beta-D-Glc-(1<->1)-ceramide + UDP-N-acetyl-alpha-D-galactosamine = a beta-D-GalNAc-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Man-(1->4)-beta-D-Glc-(1<->1)-Cer + UDP + H(+)

Direction not assertedBalance undeterminableRhea 86247

an N-acetyl-beta-D-galactosaminyl derivative + UDP-N-acetyl-alpha-D-galactosamine = an N-acetyl-alpha-D-galactosaminyl-(1->4)-N-acetyl-beta-D-galactosaminyl derivative + UDP + H(+)

Direction not assertedBalance undeterminableRhea 86251

a beta-D-GalNAc-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Man-(1->4)-beta-D-Glc-(1<->1)-Cer + UDP-N-acetyl-alpha-D-galactosamine = an alpha-D-GalNAc-(1->4)-beta-D-GalNAc-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Man-(1->4)-beta-D-Glc-(1<->1)-Cer + UDP + H(+)

Direction not assertedBalance undeterminableRhea 86255

[protein]-C-terminal carboxyl phosphoethanolamide-(1-radyl-2-octadecanoyl)-GPI(deacylinositol-H7) + H2O = [protein]-C-terminal carboxyl phosphoethanolamide-glycosylinositol-1-phosphate (deacylinositol-H7) + 1-radyl-2-octadecanoyl-sn-glycerol + H(+)

Left to rightBalance undeterminableRhea 86259

[protein]-C-terminal carboxyl phosphoethanolamide-(1-radyl-2-octadecanoyl)-GPI(deacylinositol-H7) + H2O = [protein]-C-terminal carboxyl phosphoethanolamide-glycosylinositol (deacylinositol-H7) + 1-radyl-2-octadecanoyl-sn-glycero-3-phosphate + H(+)

Left to rightBalance undeterminableRhea 86263

[protein]-disulfide + 2 L-cysteine = [protein]-dithiol + L-cystine

Left to rightBalance undeterminableRhea 86267

(4S)-4-hydroxy-2-oxoglutarate + NAD(+) + CoA = (S)-malyl-CoA + CO2 + NADH

Direction not assertedBalancedRhea 86299

(S)-malate + GTP + CoA = (S)-malyl-CoA + GDP + phosphate

Direction not assertedBalancedRhea 86303

itaconate + GTP + CoA = itaconyl-CoA + GDP + phosphate

Direction not assertedBalancedRhea 86307

itaconate + ATP + CoA = itaconyl-CoA + ADP + phosphate

Direction not assertedBalancedRhea 86311

2 L-cysteinylglycine + [protein]-disulfide = L-cystine-bis-glycine + [protein]-dithiol

Left to rightBalance undeterminableRhea 86315

DNA(n) + dCTP = DNA(n)-C + diphosphate

Left to rightBalance undeterminableRhea 86319

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