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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

18,251–18,300 of 18,558 reactions from Rhea

an N(4)-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->4)]-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-alpha-D-galactose = an N(4)-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->4)]-[beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)
Left to rightBalance undeterminableRhea 85471
acetoin + 2-phenylethylamine = schleiferon A + H2O
Direction not assertedBalancedRhea 85475
6-carboxymethyl-3,5-dimethyl-4-hydroxypyridin-2-ol + GTP + H(+) = guanylylpyridinol + diphosphate
Direction not assertedBalancedRhea 85479
6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol + S-adenosyl-L-methionine = 6-carboxymethyl-3,5-dimethyl-4-hydroxypyridin-2-ol + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 85483
guanylylpyridinol + ATP + H(+) = guanylylpyridinol-AMP + diphosphate
Direction not assertedBalancedRhea 85487
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + a 1,2-diacyl-sn-glycero-3-phosphocholine(in) = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + a 1,2-diacyl-sn-glycero-3-phosphocholine(out)

Direction not assertedBalance undeterminableTransportRhea 85491

N-acetylneuraminate + S-adenosyl-L-methionine = N-acetyl-8-O-methylneuraminate + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 85499

methyl nicotinate + H2O = nicotinate + methanol + H(+)

Direction not assertedBalancedRhea 85503

(8S)-8-amino-7-oxononanoate + spermidine = N-(3-aminopropyl)-4-aminobutanal + (7R,8S)-7,8-diammoniononanoate

Direction not assertedBalancedRhea 85507

2 chloride(out) + Na(+)(out) + NH4(+)(out) = 2 chloride(in) + Na(+)(in) + NH4(+)(in)

Direction not assertedBalancedTransportRhea 85511

(3S,5S)-carbapenam-3-caboxylate + (R)-pantetheine + S-adenosyl-L-methionine = (2R,3R,5R)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + 5'-deoxyadenosine + L-methionine + H(+)

Direction not assertedBalancedRhea 85515

L-lysyl(56)-[histone H3] + S-adenosyl-L-methionine = N(6)-methyl-L-lysyl(56)-[histone H3] + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 85519

3beta-hydroxy-5alpha-androstane 17-O-(beta-D-glucuronate) + NADP(+) = 5alpha-dihydrotestosterone 17-O-(beta-D-glucuronate) + NADPH + H(+)

Right to leftBalancedRhea 85523

N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + D-xylulose 5-phosphate + holo-[ACP] = glycoloyl-[ACP] + N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + D-glyceraldehyde 3-phosphate

Direction not assertedBalance undeterminableRhea 85527

5alpha-androstan-3,11,17-trione + NADPH + H(+) = 17beta-hydroxy-5alpha-androstan-3,11-dione + NADP(+)

Left to rightBalancedRhea 85531

(2E,6E)-farnesyl diphosphate = (-)-dauca-4(11),8-diene + diphosphate

Direction not assertedBalancedRhea 85535

(-)-dauca-4(11),8-diene + 4 reduced [NADPH--hemoprotein reductase] + 4 O2 = (8R,9S)-8,9-epoxydauca-4(11)ene-8-oate + 4 oxidized [NADPH--hemoprotein reductase] + 5 H2O + 5 H(+)

Direction not assertedBalance undeterminableRhea 85539

3alpha-hydroxy-5alpha-androstan-11,17-dione + NADPH + H(+) = 3alpha,17beta-dihydroxy-5alpha-androstan-11-one + NADP(+)

Left to rightBalancedRhea 85543

(8R,9S)-8,9-epoxydauca-4(11)ene-8-oate + reduced [NADPH--hemoprotein reductase] + O2 = aspterrate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 85547

5alpha-androstan-3,11,17-trione + NADPH + H(+) = 3alpha-hydroxy-5alpha-androstan-11,17-dione + NADP(+)

Left to rightBalancedRhea 85551

5alpha-androstan-3,11,17-trione + NADPH + H(+) = 3beta-hydroxy-5alpha-androstan-11,17-dione + NADP(+)

Left to rightBalancedRhea 85555

17beta-hydroxy-5alpha-androstan-3,11-dione + NADPH + H(+) = 3alpha,17beta-dihydroxy-5alpha-androstan-11-one + NADP(+)

Left to rightBalancedRhea 85559

17beta-hydroxy-5alpha-androstan-3,11-dione + NADPH + H(+) = 3beta,17beta-dihydroxy-5alpha-androstan-11-one + NADP(+)

Left to rightBalancedRhea 85563

(E)-thiourocanate (thione form) + H2O = 3-(5-oxo-2-sulfanylideneimidazolidin-4-yl)propanoate

Direction not assertedBalancedRhea 85567

3-(5-oxo-2-sulfanylideneimidazolidin-4-yl)propanoate + H2O = hydantoin-5-propanoate + hydrogen sulfide + H(+)

Direction not assertedBalancedRhea 85571

D-glucose 6-phosphate = D-mannose 6-phosphate

ReversibleBalancedRhea 85575

alpha-D-fructose 6-phosphate = beta-D-fructose 6-phosphate

ReversibleBalancedRhea 85579

alpha-D-mannose 6-phosphate = beta-D-mannose 6-phosphate

ReversibleBalancedRhea 85583

hercynine + L-cysteine = ergothioneine (thione form) + L-alanine

Direction not assertedBalancedRhea 85587

(5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate = leukotriene A5 + H2O

Left to rightBalancedRhea 85591

alpha-D-galactose 6-phosphate = beta-D-galactose 6-phosphate

Direction not assertedBalancedRhea 85595

leukotriene A5 + H2O = leukotriene B5

Left to rightBalancedRhea 85599

acetamide = acetonitrile + H2O

Direction not assertedBalancedRhea 85603

propanamide = propanonitrile + H2O

Direction not assertedBalancedRhea 85607

acrylamide = acrylonitrile + H2O

Direction not assertedBalancedRhea 85611

(2E,6E)-farnesyl diphosphate = sterpurene + diphosphate

Direction not assertedBalancedRhea 85615

(2E)-geranyl diphosphate + H2O = (1R,2R)-menth-2-en-1-ol + diphosphate

Direction not assertedBalancedRhea 85619

(2E,6E)-farnesyl diphosphate + H2O = africanol + diphosphate

Direction not assertedBalancedRhea 85623

africanol + reduced [NADPH--hemoprotein reductase] + O2 = 4-hydroxyafricanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 85627

4-hydroxyafricanol + reduced [NADPH--hemoprotein reductase] + O2 = 4-oxoafricanol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 85631

4-oxoafricanol = 2-dehydroxy-2-en-4-oxoafricanol + H2O

Direction not assertedBalancedRhea 85635

2-dehydroxy-2-en-4-oxoafricanol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = ophiocerate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 85639

2-hydroxyacetamide = 2-hydroxyacetonitrile + H2O

Direction not assertedBalancedRhea 85643

methoxyacetamide = methoxyacetonitrile + H2O

Direction not assertedBalancedRhea 85647

butanamide = butanenitrile + H2O

Direction not assertedBalancedRhea 85651

2-methylacrylamide = methylacrylonitrile + H2O

Direction not assertedBalancedRhea 85655

nicotinamide = 3-cyanopyridine + H2O

Direction not assertedBalancedRhea 85659

pyridine-4-carboxamide = 4-cyanopyridine + H2O

Direction not assertedBalancedRhea 85663

benzamide = benzonitrile + H2O

Direction not assertedBalancedRhea 85667

crotonoamide = crotononitrile + H2O

Direction not assertedBalancedRhea 85671

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