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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSource

Reactions

18,101–18,150 of 31,435, by identifier

alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose
Direction not assertedBalancedRhea 32675
(2E)-geranyl diphosphate + H2O = (2E)-geraniol + diphosphate
Direction not assertedBalancedRhea 32679
5-hydroxymethylfurfural + 3 O2 + 2 H2O = 2,5-dicarboxyfuran + 3 H2O2 + 2 H(+)
Direction not assertedBalancedRhea 32683
(2E)-geranyl diphosphate = tricyclene + diphosphate
Direction not assertedBalancedRhea 32687
(2E)-geranyl diphosphate = (E)-beta-ocimene + diphosphate
Direction not assertedBalancedRhea 32691
(2E)-geranyl diphosphate = (-)-car-3-ene + diphosphate
Direction not assertedBalancedRhea 32695
(2E,6E)-farnesyl diphosphate = beta-sesquiphellandrene + diphosphate

? Direction not asserted

Balanced

Rhea 32699

(2E,6E,10E)-geranylgeranyl diphosphate + H2O = 8-hydroxycopalyl diphosphate

Direction not assertedBalancedRhea 32703

(2E)-geranyl diphosphate = (2R,4S)-bornyl diphosphate

Direction not assertedBalancedRhea 32707

a (3R)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + NADH + H(+)

Left to rightBalance undeterminableRhea 32711

(2R,3S)-3-methylmalate + NAD(+) = 2-oxobutanoate + CO2 + NADH

Direction not assertedBalancedRhea 32715

L-dihomomethionine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (E)-5-(methylsulfanyl)pentanal oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 32719

L-trihomomethionine + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = (E)-6-(methylsulfanyl)hexanal oxime + 2 oxidized [NADPH--hemoprotein reductase] + CO2 + 3 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 32723

a very-long-chain acyl-CoA + malonyl-CoA + H(+) = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA

Left to rightBalance undeterminableRhea 32727

a diacylglycerol + H2O = a monoacylglycerol + a fatty acid + H(+)

Left to rightBalance undeterminableRhea 32731

a 1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 32735

a 1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = a 1,2-diacyl-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalance undeterminableRhea 32739

O-acetyl-L-serine + L-homocysteine = L,L-cystathionine + acetate + H(+)

Direction not assertedBalancedRhea 32743

ethanolamine(in) = ethanolamine(out)

Direction not assertedBalancedTransportRhea 32747

choline(out) = choline(in)

Direction not assertedBalancedTransportRhea 32751

(2S)-naringenin + 2-oxoglutarate + O2 = apigenin + succinate + CO2 + H2O + H(+)

Direction not assertedBalancedRhea 32755

L-lysine = (3R)-3-methyl-D-ornithine

Direction not assertedBalancedRhea 32759

(3R)-3-methyl-D-ornithine + L-lysine + ATP = (3R)-3-methyl-D-ornithyl-N(6)-L-lysine + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 32763

cytidine(4) in tRNA(Pro) + S-adenosyl-L-methionine = 2'-O-methylcytidine(4) in tRNA(Pro) + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 32767

2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate = 2,6-dioxo-6-phenylhexa-3-enoate

Direction not assertedBalancedRhea 32771

(2-aminoethyl)phosphonate(out) + ATP + H2O = (2-aminoethyl)phosphonate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 32775

Co(2+)(out) + ATP + H2O = Co(2+)(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 32779

glycine betaine(out) + ATP + H2O = glycine betaine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 32783

L-ectoine(out) + ATP + H2O = L-ectoine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 32787

L-ectoine(in) = L-ectoine(out)

Direction not assertedBalancedTransportRhea 32791

L-cysteine(out) + ATP + H2O = L-cysteine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 32795

urea(in) = urea(out)

Direction not assertedBalancedTransportRhea 32799

urea(out) + ATP + H2O = urea(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 32803

thiosulfate(in) = thiosulfate(out)

Direction not assertedBalancedTransportRhea 32807

benzoate(in) = benzoate(out)

Direction not assertedBalancedTransportRhea 32811

Hg(2+)(in) = Hg(2+)(out)

Direction not assertedBalancedTransportRhea 32815

chromate(in) = chromate(out)

Direction not assertedBalancedTransportRhea 32819

phosphate(in) = phosphate(out)

Left to rightBalancedTransportRhea 32823

methionine(out) + ATP + H2O = methionine(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 32827

an R-cob(III)alamin(in) = an R-cob(III)alamin(out)

Direction not assertedBalance undeterminableTransportRhea 32831

4-(trimethylamino)butanoate(in) = 4-(trimethylamino)butanoate(out)

Direction not assertedBalancedTransportRhea 32835

a 1,2-diacyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a triacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 32843

a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol = a triacyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphoethanolamine

Direction not assertedBalance undeterminableRhea 32847

a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1-acyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 32851

a 2-acylglycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 32855

a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1-acyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 32859

a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 32863

myo-inositol(out) = myo-inositol(in)

Direction not assertedBalancedTransportRhea 32867

a 2-acylglycerol + H2O = a carboxylate + glycerol + H(+)

Direction not assertedBalance undeterminableRhea 32871

a 1-acyl-sn-glycerol + H2O = glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 32875

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