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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

17,701–17,750 of 18,558 reactions from Rhea

2,22-dideoxyecdysone + 2 reduced [adrenodoxin] + O2 + 2 H(+) = 22-deoxyecdysone + 2 oxidized [adrenodoxin] + H2O
Direction not assertedBalance undeterminableRhea 83255
N-acetyl-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioyl-D-alanyl-D-alanine + H2O = N-acetyl-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioyl-D-alanine + D-alanine
Direction not assertedBalancedRhea 83259
N-acetyl-beta-D-glucosaminyl-N-acetyl-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioyl-D-alanyl-D-alanine + H2O = N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-meso-2,6-diaminoheptanedioyl-D-alanine + D-alanine
Direction not assertedBalancedRhea 83263
UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioyl-D-alanine + H2O = UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimelate + D-alanine
Direction not assertedBalancedRhea 83267
N-acetyl-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioyl-D-alanine + H2O = N-acetyl-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanine
Direction not assertedBalancedRhea 83271

okaramine A + 2-oxoglutarate + O2 = okaramine E + succinate + CO2

Direction not assertedBalancedRhea 83275

uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)

Left to rightBalancedRhea 83279

(2E,6E)-farnesyl diphosphate = beta-gurjunene + diphosphate

Direction not assertedBalancedRhea 83287

(11Z)-docosenoyl-CoA(4-) + oxidized [electron-transfer flavoprotein] + H(+) = (2E,11Z)-docosadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 83291

3-dehydro-2,22-dideoxyecdysone + 2 reduced [adrenodoxin] + O2 + 2 H(+) = 3-dehydro-2-deoxyecdysone + 2 oxidized [adrenodoxin] + H2O

Direction not assertedBalance undeterminableRhea 83295

3-dehydro-2,22,25-deoxyecdysone + 2 reduced [adrenodoxin] + O2 + 2 H(+) = 2,25-dideoxy-3-dehydroecdysone + 2 oxidized [adrenodoxin] + H2O

Direction not assertedBalance undeterminableRhea 83299

N-glycoloylneuraminate 9-phosphate + H2O = N-glycoloylneuraminate + phosphate

Left to rightBalancedRhea 83303

pyrrolizixenacetamide + H2O = 3-amino-5,6,7,7a-tetrahydro-1H-pyrrolizin-1-one + acetate + H(+)

Direction not assertedBalancedRhea 83307

3-amino-5,6,7,7a-tetrahydro-1H-pyrrolizin-1-one + AH2 = 3-amino-tetrahydro-1H-pyrrolizin-1-ol + A

Direction not assertedBalancedRhea 83311

D-glycero-beta-D-manno-heptose 1-phosphate + CTP + H(+) = CDP-D-glycero-beta-D-manno-heptose + diphosphate

Direction not assertedBalancedRhea 83315

D-glycero-beta-D-manno-heptose 1-phosphate + UTP + H(+) = UDP-D-glycero-beta-D-manno-heptose + diphosphate

Direction not assertedBalancedRhea 83319

(2E,11Z)-docosadienoyl-CoA + H2O = (3S)-hydroxy-(11Z)-docosenoyl-CoA

Direction not assertedBalancedRhea 83323

(3S)-hydroxy-(11Z)-docosenoyl-CoA + NAD(+) = 3-oxo-(11Z)-docosenoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 83327

3-oxo-(11Z)-docosenoyl-CoA + CoA = (9Z)-eicosenoyl-CoA + acetyl-CoA

Direction not assertedBalancedRhea 83331

(9Z)-eicosenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9Z)-eicosadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 83335

serotonin + 3'-phosphoadenylyl sulfate = serotonin O-sulfate + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 83339

(R)-adrenaline + 3'-phosphoadenylyl sulfate = (R)-adrenaline 4'-O-sulfate + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 83343

(9Z)-eicosenoate + ATP + CoA = (9Z)-eicosenoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 83347

(R)-noradrenaline + 3'-phosphoadenylyl sulfate = (R)-noradrenaline 4'-O-sulfate + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 83351

(9Z)-eicosenoyl-CoA + H2O = (9Z)-eicosenoate + CoA + H(+)

Direction not assertedBalancedRhea 83355

(2E,9Z)-eicosadienoyl-CoA + H2O = (3S)-hydroxy-(9Z)-eicosenoyl-CoA

Left to rightBalancedRhea 83359

(3S)-hydroxy-(9Z)-eicosenoyl-CoA + NAD(+) = 3-oxo-(9Z)-eicosenoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 83363

3-oxo-(9Z)-eicosenoyl-CoA + CoA = (7Z)-octadecenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 83367

(7Z)-octadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,7Z)-octadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 83371

(2E,7Z)-octadecadienoyl-CoA + H2O = (3S)-hydroxy-(7Z)-octadecenoyl-CoA

Left to rightBalancedRhea 83375

(3S)-hydroxy-(7Z)-octadecenoyl-CoA + NAD(+) = 3-oxo-(7Z)-octadecenoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 83379

3-oxo-(7Z)-octadecenoyl-CoA + CoA = (5Z)-hexadecenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 83383

(5Z)-hexadecenoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,5Z)-hexadecadienoyl-CoA + reduced [electron-transfer flavoprotein]

Left to rightBalance undeterminableRhea 83387

(2E,5Z)-hexadecadienoyl-CoA + H2O = (3S)-hydroxy-(5Z)-hexadecenoyl-CoA

Left to rightBalancedRhea 83391

(3S)-hydroxy-(5Z)-hexadecenoyl-CoA + NAD(+) = 3-oxo-(5Z)-hexadecenoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 83395

3-oxo-(5Z)-hexadecenoyl-CoA + CoA = (3Z)-tetradecenoyl-CoA + acetyl-CoA

Left to rightBalancedRhea 83399

(11Z)-docosenoate + ATP + CoA = (11Z)-docosenoyl-CoA(4-) + AMP + diphosphate

Direction not assertedBalancedRhea 83403

L-citrulline + H(+) = isocyanate + L-ornithine

Left to rightBalancedRhea 83407

(13Z)-docosenoyl-CoA + H2O = (13Z)-docosenoate + CoA + H(+)

Direction not assertedBalancedRhea 83411

2',3'-cGAMP + H2O = 5'-O-phosphonoguanyl-(2'->5')-adenosine + H(+)

Direction not assertedBalancedRhea 83415

guanosine(7) in tRNA + S-adenosyl-L-methionine = N(2)-methylguanosine(7) in tRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 83419

guanosine in U6 snRNA + S-adenosyl-L-methionine = N(2)-methylguanosine in U6 snRNA + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 83423

3',3'-c-di-AMP + 2 H2O = 2 AMP + 2 H(+)

Direction not assertedBalancedRhea 83427

5'-O-phosphonoguanyl-(2'->5')-adenosine + H2O = GMP + AMP + H(+)

Direction not assertedBalancedRhea 83431

D-beta-lysine + L-lysyl-[protein] + ATP = N(6)-((3R)-3,6-diaminohexanoyl)-L-lysyl-[protein] + AMP + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 83435

N(6)-((3R)-3,6-diaminohexanoyl)-L-lysyl-[protein] + NADPH + O2 + H(+) = N(6)-((3R)-3,6-diaminohexanoyl)-5-hydroxy-L-lysyl-[protein] + NADP(+) + H2O

Direction not assertedBalance undeterminableRhea 83439

N(alpha)-formyl-L-methionyl-L-leucyl-L-phenylalanine + H2O = L-leucyl-L-phenylalanine + N(alpha)-formyl-L-methionine

Left to rightBalancedRhea 83443

a neolactoside IV(3)-beta-GlcNAc-nLc4Cer(d18:1(4E)) + UDP-alpha-D-galactose = a neolactoside nLc6Cer(d18:1(4E)) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 83447

L-valine + ATP + NADPH + H(+) = L-valinal + AMP + diphosphate + NADP(+)

Direction not assertedBalancedRhea 83455

L-tryptophanal + L-valinal = didehydrocampesine A + 2 H2O + H(+)

Direction not assertedBalancedRhea 83459

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