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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

17,401–17,450 of 18,558 reactions from Rhea

nocardicin C + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 2 H(+) = nocardicin A + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O
Direction not assertedBalance undeterminableRhea 82031
nocardicin C + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) = 2'-N-hydroxynocardicin C + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Direction not assertedBalance undeterminableRhea 82035
2'-N-hydroxynocardicin C + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 2'-N,N-dihydroxynocardicin C + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O
Direction not assertedBalance undeterminableRhea 82039
2'-N,N-dihydroxynocardicin C = nocardicin A + H2O + H(+)
Direction not assertedBalancedRhea 82043
L-2-aminoadipate(in) + L-glutamate(out) + H(+)(out) = L-2-aminoadipate(out) + L-glutamate(in) + H(+)(in)
Direction not assertedBalancedTransportRhea 82047
L-leucyl-tRNA(Leu) + acetyl-CoA = N-acetyl-L-leucyl-tRNA(Leu) + CoA + H(+)
Direction not asserted

Balanced

Rhea 82051

2,22-dideoxyecdysone + 2 reduced [adrenodoxin] + O2 + 2 H(+) = 2-deoxyecdysone + 2 oxidized [adrenodoxin] + H2O

Direction not assertedBalance undeterminableRhea 82055

L-alpha-aminoacyl-tRNA + acetyl-CoA = N-acetyl-L-alpha-aminoacyl-tRNA + CoA + H(+)

Direction not assertedBalance undeterminableRhea 82059

L-tryptophyl-tRNA(Trp) + acetyl-CoA = N-acetyl-L-tryptophyl-tRNA(Trp) + CoA

Direction not assertedBalancedRhea 82063

L-cysteinyl-tRNA(Cys) + acetyl-CoA = N-acetyl-L-cysteinyl-tRNA(Cys) + CoA + H(+)

Direction not assertedBalancedRhea 82067

L-glutaminyl-tRNA(Gln) + acetyl-CoA = N-acetyl-L-glutaminyl-tRNA(Gln) + CoA + H(+)

Direction not assertedBalancedRhea 82071

L-seryl-tRNA(Ser) + acetyl-CoA = N-acetyl-L-seryl-tRNA(Ser) + CoA

Direction not assertedBalancedRhea 82075

L-phenylalanyl-tRNA(Phe) + acetyl-CoA = N-acetyl-L-phenylalanyl-tRNA(Phe) + CoA

Direction not assertedBalancedRhea 82079

L-alanyl-tRNA(Ala) + acetyl-CoA = N-acetyl-L-alanyl-tRNA(Ala) + CoA + H(+)

Direction not assertedBalancedRhea 82083

L-asparaginyl-tRNA(Asn) + acetyl-CoA = N-acetyl-L-asparaginyl-tRNA(Asn) + CoA

Direction not assertedBalancedRhea 82087

L-tyrosyl-tRNA(Tyr) + acetyl-CoA = N-acetyl-L-tyrosyl-tRNA(Tyr) + CoA

Direction not assertedBalancedRhea 82091

a ganglioside GD3 + CMP-N-acetyl-9-O-acetyl-beta-neuraminate = a ganglioside Ac-O-9-GT3 + CMP + H(+)

Direction not assertedBalance undeterminableRhea 82095

a ganglioside GM3 + CMP-N-acetyl-9-O-acetyl-beta-neuraminate = a ganglioside Ac-O-9-GD3 + CMP + H(+)

Direction not assertedBalance undeterminableRhea 82099

nitric oxide + L-tryptophan + reduced [2Fe-2S]-[ferredoxin] + O2 + H(+) = 4-nitro-L-tryptophan zwitterion + oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 82103

L-Met-L-Arg-L-Tyr-L-Leu-L-His + nitric oxide + reduced [2Fe-2S]-[ferredoxin] + O2 = L-Met-L-Arg-(3-NO2)-L-Tyr-L-Leu-L-His + oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 82107

4alpha,5beta-5,20-epoxytax-11-ene-4,9-diol + 2-oxoglutarate + O2 = 4alpha-hydroxy-5beta-5,20-epoxytax-11-en-9-one + succinate + CO2 + H2O

Direction not assertedBalancedRhea 82111

a ganglioside GD3 (d18:1(4E)) + CMP-N-acetyl-9-O-acetyl-beta-neuraminate = a ganglioside Ac-O-9-GT3 (d18:1(4E)) + CMP + H(+)

Direction not assertedBalance undeterminableRhea 82115

CMP-N-acetyl-9-O-acetyl-beta-neuraminate + a ganglioside GM3 (d18:1(4E)) = a ganglioside Ac-O-9-GD3(d18:1(4E)) + CMP + H(+)

Direction not assertedBalance undeterminableRhea 82119

a 3-O-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-alpha-D-GalNAc}-L-threonyl-[protein] + CMP-N-acetyl-beta-neuraminate = a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-alpha-D-GalNAc}-L-threonyl-[protein] + CMP + H(+)

Direction not assertedBalance undeterminableRhea 82123

a 3-O-{beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-alpha-D-galactosaminyl}-L-threonyl-[protein] + UDP-alpha-D-galactose = a 3-O-{beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-alpha-D-GalNAc}-L-threonyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 82127

scyllo-inositol 1-phosphate + H2O = scyllo-inositol + phosphate

Left to rightBalancedRhea 82131

CMP-N-acetyl-9-O-acetyl-beta-neuraminate + a ganglioside GM1 (d18:1(4E)) = a ganglioside Ac-O-9-GD1a (d18:1(4E)) + CMP + H(+)

Direction not assertedBalance undeterminableRhea 82135

CMP-N-acetyl-9-O-acetyl-beta-neuraminate + a ganglioside GM1 = a ganglioside Ac-O-9-GD1a + CMP + H(+)

Direction not assertedBalance undeterminableRhea 82139

a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-alpha-D-GalNAc}-L-threonyl-[protein] + GDP-beta-L-fucose = a 3-O-{alpha-Neu5Ac-(2->3)-beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-(1->6)-[beta-D-Gal-(1->3)]-alpha-D-GalNAc}-L-threonyl-[protein] + GDP + H(+)

Direction not assertedBalance undeterminableRhea 82143

holo-[peptidyl-carrier protein] + L-lysine + ATP = L-lysyl-[peptidyl-carrier protein] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 82147

(S)-1-pyrroline-5-carboxylate + L-arginine + S-adenosyl-L-methionine + 2 ATP = peramine + 2 AMP + S-adenosyl-L-homocysteine + 2 diphosphate + H2O + 2 H(+)

Direction not assertedBalancedRhea 82151

L-lysyl-5'-AMP + holo-[peptidyl-carrier protein] = L-lysyl-[peptidyl-carrier protein] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 82155

L-proline + 2-oxoglutarate + O2 = trans-3-hydroxy-L-proline + succinate + CO2

Direction not assertedBalancedRhea 82159

D-proline + 2-oxoglutarate + O2 = cis-4-hydroxy-D-proline + succinate + CO2

Direction not assertedBalancedRhea 82163

peramine + 2-oxoglutarate + O2 = 8-hydroxyperamine + succinate + CO2

Direction not assertedBalancedRhea 82167

L-lysyl-[peptidyl-carrier protein] + 2 (3R)-3-isocyanylbutanoyl-[ACP] + 2 NADPH = (2S)-2,6-bis[(3R)-3-isocyanobutanamido]hexan-1-ol + holo-[peptidyl-carrier protein] + 2 holo-[ACP] + 2 NADP(+)

Direction not assertedBalance undeterminableRhea 82171

a 3'-hydroxyisoflavone + S-adenosyl-L-methionine = a 3'-methoxyisoflavone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 82175

exophillate aglycone + UDP-alpha-D-glucose = exophillate + UDP + H(+)

Direction not assertedBalancedRhea 82179

3',4',7-trihydroxyisoflavone + S-adenosyl-L-methionine = 7,4'-dihydroxy-3'-methoxyisoflavone-7-olate + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 82183

trans-resveratrol + S-adenosyl-L-methionine = 4'-O-methyl-trans-resveratrol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 82187

piceatannol + S-adenosyl-L-methionine = rhapontigenin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 82191

L-valine + L-arginine = N-amidino-L-valine + L-ornithine

Direction not assertedBalancedRhea 82195

verapyrone B aglycone + UDP-alpha-D-galactose = verapyrone B + UDP + 2 H(+)

Direction not assertedBalancedRhea 82199

exophillate + UDP-alpha-D-galactose = phaeomoniecin D + UDP + H(+)

Direction not assertedBalancedRhea 82203

2 L-arginine = N-amidino-L-arginine + L-ornithine

Direction not assertedBalancedRhea 82207

a cytidine in RNA + acetyl-CoA + ATP + H2O = an N(4)-acetylcytidine in RNA + ADP + phosphate + CoA + H(+)

Direction not assertedBalance undeterminableRhea 82211

isorhapontigenin + S-adenosyl-L-methionine = 4'-O-methylisorhapontigenin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 82215

L-cysteine + L-arginine = N-amidino-L-cysteine + L-ornithine

Direction not assertedBalancedRhea 82219

L-isoleucine + L-arginine = N-amidino-L-isoleucine + L-ornithine

Direction not assertedBalancedRhea 82223

L-leucine + L-arginine = N-amidino-L-leucine + L-ornithine

Direction not assertedBalancedRhea 82227

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