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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

17,151–17,200 of 18,558 reactions from Rhea

N-methyl-3,4-dihydroxy-5-methoxyphenethylamine + S-adenosyl-L-methionine = N,N-dimethyl-3,4-dihydroxy-5-methoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 81015
3-hydroxy-4,5-dimethoxyphenethylamine + S-adenosyl-L-methionine = N-methyl-3-hydroxy-4,5-dimethoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 81019
N-methyl-3-hydroxy-4,5-dimethoxyphenethylamine + S-adenosyl-L-methionine = N,N-dimethyl-3-hydroxy-4,5-dimethoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 81023
4-hydroxy-3,5-dimethoxyphenethylamine + S-adenosyl-L-methionine = N-methyl-4-hydroxy-3,5-dimethoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 81027
N-methyl-4-hydroxy-3,5-dimethoxyphenethylamine + S-adenosyl-L-methionine = N,N-dimethyl-4-hydroxy-3,5-dimethoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 81031
mescaline + S-adenosyl-L-methionine = N-methylmescaline + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 81035

N-methylmescaline + S-adenosyl-L-methionine = N,N-dimethylmescaline + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 81039

3,4-dihydroxy-5-methoxyphenethylamine + S-adenosyl-L-methionine = 4-hydroxy-3,5-dimethoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 81043

dopamine + S-adenosyl-L-methionine = 4-methoxytyramine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 81047

3,4-dihydroxy-5-methoxyphenethylamine + S-adenosyl-L-methionine = 3-hydroxy-4,5-dimethoxyphenethylamine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 81051

3-hydroxy-4,5-dimethoxyphenethylamine + S-adenosyl-L-methionine = mescaline + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 81055

4-hydroxy-3,5-dimethoxyphenethylamine + S-adenosyl-L-methionine = mescaline + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 81059

L-tyrosine + reduced [NADPH--hemoprotein reductase] + O2 = L-dopa + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 81063

7beta,14,16-trihydroxyconfertifolin + benzoate + H(+) = dideacetyl astellolide A + H2O

Direction not assertedBalancedRhea 81067

7beta,14,16-trihydroxyconfertifolin + 4-hydroxybenzoate + H(+) = dideacetyl astellolide B + H2O

Direction not assertedBalancedRhea 81071

dideacetyl astellolide A + acetyl-CoA = 14-deacetyl astellolide A + CoA

Direction not assertedBalancedRhea 81075

dideacetyl astellolide B + acetyl-CoA = 14-deacetyl astellolide B + CoA

Direction not assertedBalancedRhea 81079

hancockiamide D + (E)-cinnamate + ATP = hancockiamide A + AMP + diphosphate

Direction not assertedBalancedRhea 81083

hancockiamide A + reduced [NADPH--hemoprotein reductase] + O2 = hancockiamide G + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 81087

a cardiolipin + NAD(+) = a diphosphatidylglycerone + NADH + H(+)

Direction not assertedBalance undeterminableRhea 81091

1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + NAD(+) = 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerone + NADH + H(+)

Direction not assertedBalancedRhea 81095

a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + NAD(+) = a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerone) + NADH + H(+)

Direction not assertedBalance undeterminableRhea 81099

(2E,6E)-farnesyl diphosphate = (5S,9S,10S)-drim-7-en-11-yl diphosphate

Direction not assertedBalancedRhea 81103

N-acetyltaurine + H2O = taurine + acetate

Left to rightBalancedRhea 81107

N-propanoyltaurine + H2O = propanoate + taurine

Left to rightBalancedRhea 81111

N-acetyl-L-leucine + H2O = L-leucine + acetate

Left to rightBalancedRhea 81115

N-acetyl-L-isoleucine + H2O = L-isoleucine + acetate

Left to rightBalancedRhea 81119

N-acetyl-L-valine + H2O = L-valine + acetate

Left to rightBalancedRhea 81123

hancockiamide B + reduced [NADPH--hemoprotein reductase] + O2 = hancockiamide C + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 81127

hancockiamide D + reduced [NADPH--hemoprotein reductase] + O2 = hancockiamide H + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 81131

hancockiamide H + (E)-cinnamate + ATP = hancockiamide G + AMP + diphosphate

Direction not assertedBalancedRhea 81135

hancockiamide A + acetyl-CoA = hancockiamide B + CoA + H(+)

Direction not assertedBalancedRhea 81139

hancockiamide G + acetyl-CoA = hancockiamide C + CoA + H(+)

Direction not assertedBalancedRhea 81143

holo-[ACP] + 8 malonyl-CoA + acetyl-CoA + 5 AH2 + 8 NADPH + 16 H(+) = (3R)-hydroxyoctadeca-4,10-dienoyl-[ACP] + 5 A + 8 CO2 + 8 NADP(+) + 9 CoA + 7 H2O

Direction not assertedBalance undeterminableRhea 81147

aminomalonate + (3R)-hydroxyoctadeca-4,10-dienoyl-[ACP] = 3-oxopresphingofungin + holo-[ACP] + CO2

Direction not assertedBalance undeterminableRhea 81151

3-oxopresphingofungin + 2 H(+) = decarboxy 3-dehydropresphingofungin + CO2

Direction not assertedBalancedRhea 81155

3-oxopresphingofungin + NADPH + 2 H(+) = presphingofungin + NADP(+)

Direction not assertedBalancedRhea 81159

presphingofungin + 2 reduced [NADPH--hemoprotein reductase] + O2 = sphingofungin B1 + 2 oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 81163

sphingofungin B1 + 2-oxoglutarate + O2 = sphingofungin B + succinate + CO2

Direction not assertedBalancedRhea 81167

sphingofungin B + acetyl-CoA = sphingofungin C + CoA

Direction not assertedBalancedRhea 81171

N(3)-1,2-dicarboxyethyl-diaminobutanoate = (2S,3R)-diaminobutanoate + fumarate

Direction not assertedBalancedRhea 81175

a 4-hydroxy-3-methoxy-5-(all-trans-polyprenyl)benzoate + H(+) = a 2-methoxy-6-(all-trans-polyprenyl)phenol + CO2

Direction not assertedBalance undeterminableRhea 81179

a 2-methoxy-6-(all-trans-polyprenyl)phenol + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a 2-methoxy-6-(all-trans-polyprenyl)benzene-1,4-diol + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 81183

O-phospho-L-threonine + L-aspartate = N(3)-1,2-dicarboxyethyl-diaminobutanoate + phosphate + H(+)

Direction not assertedBalancedRhea 81187

aminoacetaldehyde + NAD(+) + H2O = glycine + NADH + 2 H(+)

Direction not assertedBalancedRhea 81191

a 4-hydroxy-3-(all-trans-polyprenyl)benzoate + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = a 3,4-dihydroxy-5-(all-trans-polyprenyl)benzoate + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 81195

a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzene-1,4-diol + A = a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzoquinone + AH2

Direction not assertedBalance undeterminableRhea 81207

a 5-methoxy-2-methyl-3-(all-trans-polyprenyl)benzoquinone + NADH + O2 = a 3-demethylubiquinone + NAD(+) + H2O

Left to rightBalance undeterminableRhea 81211

a 3-demethylubiquinone + S-adenosyl-L-methionine = a ubiquinone + S-adenosyl-L-homocysteine

Direction not assertedBalance undeterminableRhea 81215

ent-copalyl diphosphate = ent-trachylobane + diphosphate

Direction not assertedBalancedRhea 81219

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