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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
Proteins
Interactions
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Chemistry

Reactions
Reach

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Processes
Anatomy
Cell types
Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

16,851–16,900 of 18,558 reactions from Rhea

a ganglioside GT1aalpha (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)
Direction not assertedBalance undeterminableRhea 79807
a ganglioside GD1b + acetyl-CoA = a ganglioside Ac-O-7-GD1b + CoA
Direction not assertedBalance undeterminableRhea 79811
a ganglioside Ac-O-7-GD1b = a ganglioside Ac-O-8-GD1b
Direction not assertedBalance undeterminableRhea 79815
L-ribulose 5-phosphate + H2O = L-ribulose + phosphate
Direction not assertedBalancedRhea 79819
a ganglioside Ac-O-8-GD1b = a ganglioside Ac-O-9-GD1b
Direction not assertedBalance undeterminableRhea 79823
(R)-malate + a quinone = enol-oxaloacetate + a quinol
Left to rightBalance undeterminableRhea 79827
(S)-malate + a quinone = enol-oxaloacetate + a quinol

Left to rightBalance undeterminableRhea 79831

sulfosungeidine E = sungeidine B + sulfate + H(+)

Direction not assertedBalancedRhea 79835

L-homoarginine + 2-oxoglutarate + O2 = 6-hydroxy-L-homoarginine + succinate + CO2

Direction not assertedBalancedRhea 79839

6-hydroxy-L-homoarginine = guanidine + (S)-2-amino-6-oxohexanoate

Direction not assertedBalancedRhea 79843

L-tyrosyl-tRNA(Tyr) + L-arginyl-tRNA(Arg) = cyclo(L-arginyl-L-tyrosyl) + tRNA(Tyr) + tRNA(Arg) + H(+)

Direction not assertedBalance undeterminableRhea 79847

S-sulfanylglutathione + glutathione = glutathione disulfide + hydrogen sulfide + H(+)

Direction not assertedBalancedRhea 79851

GTP + CMP = CDP + GDP

Direction not assertedBalancedRhea 79855

CDP + GTP = CTP + GDP

Direction not assertedBalancedRhea 79859

GTP + UDP = UTP + GDP

Direction not assertedBalancedRhea 79863

dTDP + GTP = dTTP + GDP

Direction not assertedBalancedRhea 79867

dADP + GTP = dATP + GDP

Direction not assertedBalancedRhea 79871

dCDP + GTP = dCTP + GDP

Direction not assertedBalancedRhea 79875

a ribonucleoside 5'-diphosphate + GTP = a ribonucleoside 5'-triphosphate + GDP

Direction not assertedBalance undeterminableRhea 79879

a 2'-deoxyribonucleoside 5'-diphosphate + GTP = a 2'-deoxyribonucleoside 5'-triphosphate + GDP

Direction not assertedBalance undeterminableRhea 79883

a ribonucleoside 5'-phosphate + GTP = a ribonucleoside 5'-diphosphate + GDP

Direction not assertedBalance undeterminableRhea 79887

2',4,4',6'-tetrahydroxychalcone = (2S)-naringenin

Direction not assertedBalancedRhea 79891

apigenin + reduced [NADPH--hemoprotein reductase] + O2 = luteolin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 79895

dATP + AMP = dADP + ADP

Direction not assertedBalancedRhea 79899

isoliquiritigenin = (2S)-liquiritigenin

Direction not assertedBalancedRhea 79903

8-iso-prostaglandin F2alpha + UDP-alpha-D-glucuronate = 8-iso-prostaglandin F2alpha-glucuronide + UDP + H(+)

Left to rightBalancedRhea 79907

5-epi-5-F2t-IsoP + UDP-alpha-D-glucuronate = 5-epi-5-F2t-IsoP-glucuronide + UDP + H(+)

Left to rightBalancedRhea 79911

(5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP-alpha-D-glucuronate = O-[(5Z),(8Z),(11Z),(14Z)-eicosatetraenoyl]-beta-D-glucuronate + UDP

Left to rightBalancedRhea 79915

15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + UDP-alpha-D-glucuronate = 15-O-(beta-D-glucuronosyl)-(5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP + H(+)

Left to rightBalancedRhea 79919

a ganglioside GT1balpha (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1balpha (d18:1(4E)) + CMP + H(+)

Direction not assertedBalance undeterminableRhea 79923

20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP-alpha-D-glucuronate = 20-O-(beta-D-glucuronosyl)-(5Z,8Z,11Z,14Z)-eicosatetraenoate + UDP + H(+)

Left to rightBalancedRhea 79927

a ganglioside Ac-O-7-GD1b(d18:1(4E)) = a ganglioside Ac-O-8-GD1b(d18:1(4E))

Direction not assertedBalance undeterminableRhea 79931

prostaglandin B1 + UDP-alpha-D-glucuronate = 15-O-(beta-D-glucuronosyl)-prostaglandin B1 + UDP + H(+)

Left to rightBalancedRhea 79935

a ganglioside GD1b (d18:1(4E)) + acetyl-CoA = a ganglioside Ac-O-7-GD1b(d18:1(4E)) + CoA

Direction not assertedBalance undeterminableRhea 79939

a ganglioside Ac-O-8-GD1b(d18:1(4E)) = a ganglioside Ac-O-9-GD1b(d18:1(4E))

Direction not assertedBalance undeterminableRhea 79943

3-diazoavenalumate + NADPH + H(+) = avenalumate + N2 + NADP(+)

Direction not assertedBalancedRhea 79947

(E)-ferulate + UDP-alpha-D-glucuronate = (E)-4-O-(beta-D-glucuronosyl)-ferulate + UDP + H(+)

Left to rightBalancedRhea 79951

(E)-ferulate + UDP-alpha-D-glucuronate = (E)-ferulic acid beta-D-glucuronate ester + UDP

Left to rightBalancedRhea 79955

(E)-3-diazocoumarate + NADPH = N2 + (E)-4-coumarate + NADP(+)

Direction not assertedBalancedRhea 79959

a ganglioside GT1b + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b alpha + CMP + H(+)

Direction not assertedBalance undeterminableRhea 79963

3-diazoavenalumate + NADH + H(+) = avenalumate + N2 + NAD(+)

Direction not assertedBalancedRhea 79967

(E)-3-diazocoumarate + NADH = N2 + (E)-4-coumarate + NAD(+)

Direction not assertedBalancedRhea 79971

a ganglioside GM1b (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GM1b (d18:1(4E)) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79975

a ganglioside Fuc-GA1 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside Gal-(Fuc)-GA1 (d18:1(4E)) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79979

a ganglioside Gal-(Fuc)-GA1 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAcGal-(Fuc)-GA1 (d18:1(4E)) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79983

a ganglioside Fuc-GM1 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside Gal-(Fuc)-GM1 (d18:1(4E)) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79987

a ganglioside GM1 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GM1 + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79991

a ganglioside GM1 (d18:1(4E)) + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GM1 (d18:1(4E)) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79995

a ganglioside Ac-O-9-GD2 + UDP-alpha-D-galactose = a ganglioside Ac-O-9-GD1b + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79999

a ganglioside Ac-O-9-GD2(d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside Ac-O-9-GD1b(d18:1(4E)) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 80003

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