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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reactions
Reach

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Organisms
Materials
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

16,801–16,850 of 18,558 reactions from Rhea

a ganglioside Ac-O-7-GT3 = a ganglioside Ac-O-8-GT3
Direction not assertedBalance undeterminableRhea 79607
a ganglioside Ac-O-8-GT3 = a ganglioside Ac-O-9-GT3
Direction not assertedBalance undeterminableRhea 79611
rhazimol + NADP(+) = rhazimal + NADPH + 2 H(+)
Direction not assertedBalancedRhea 79615
(19E)-geissoschizine + reduced [NADPH--hemoprotein reductase] + O2 = rhazimal + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)
Direction not assertedBalance undeterminableRhea 79619
rhazimol + acetyl-CoA = akuammiline + CoA + H(+)
Direction not assertedBalancedRhea 79623
norajmaline + S-adenosyl-L-methionine = 4-methylnorajmaline + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 79627
ajmaline + S-adenosyl-L-methionine = 4-methylajmaline + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 79631

(20S)-19,20-dihydrovomilenine + NADP(+) = vomilenine + NADPH + H(+)

Direction not assertedBalancedRhea 79635

a ganglioside GD2 + acetyl-CoA = a ganglioside Ac-O-7-GD2 + CoA

Direction not assertedBalance undeterminableRhea 79639

a ganglioside Ac-O-7-GD2 = a ganglioside Ac-O-8-GD2

Direction not assertedBalance undeterminableRhea 79643

a ganglioside Ac-O-8-GD2 = a ganglioside Ac-O-9-GD2

Direction not assertedBalance undeterminableRhea 79647

3-oxoadipate + acetyl-CoA = acetoacetate + succinyl-CoA

Direction not assertedBalancedRhea 79651

3,5-dioxohexanoate + acetyl-CoA = acetoacetyl-CoA + acetoacetate

Direction not assertedBalancedRhea 79655

(2R,3R,5R)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + AH2 + 2 S-adenosyl-L-methionine = (2R,3R,5S,6R)-6-(methyl)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 79659

(2R,3R,5S,6R)-6-(methyl)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + AH2 + 2 S-adenosyl-L-methionine = (2R,3R,5S,6R)-6-(ethyl)-2-(S-pantetheinyl)-carbapenam-3-carboxylate + 5'-deoxyadenosine + L-methionine + A + S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 79663

a ganglioside GT1balpha + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b alpha + CMP + H(+)

Direction not assertedBalance undeterminableRhea 79667

a ganglioside GT1a alpha + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b alpha + CMP + H(+)

Direction not assertedBalance undeterminableRhea 79671

a ganglioside Fuc-GA1 + UDP-alpha-D-galactose = a ganglioside Gal-(Fuc)-GA1 + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79675

a ganglioside Gal-(Fuc)-GA1 + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAcGal-(Fuc)-GA1 + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79679

a ganglioside GM1b + UDP-N-acetyl-alpha-D-galactosamine = a ganglioside GalNAc-GM1b + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79683

(2E,6E,10E,14E)-geranylfarnesyl diphosphate = variecoladiene + diphosphate

Direction not assertedBalancedRhea 79687

variecoladiene + 4 reduced [NADPH--hemoprotein reductase] + 4 O2 = variecolin + 4 oxidized [NADPH--hemoprotein reductase] + 6 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 79691

(3S)-3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine = 4-(trimethylamino)butanal + glycine

Left to rightBalancedRhea 79695

1,5-bis(diphospho)-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + 2 H(+)

Direction not assertedBalancedRhea 79699

6-diphospho-1D-myo-inositol pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+)

Direction not assertedBalancedRhea 79703

a ganglioside Ac-O-8-GT3(d18:1(4E)) = a ganglioside Ac-O-9-GT3 (d18:1(4E))

Direction not assertedBalance undeterminableRhea 79707

a ganglioside GD2 (d18:1(4E)) + acetyl-CoA = a ganglioside Ac-O-7-GD2(d18:1(4E)) + CoA

Direction not assertedBalance undeterminableRhea 79711

a ganglioside Ac-O-7-GD2(d18:1(4E)) = a ganglioside Ac-O-8-GD2(d18:1(4E))

Direction not assertedBalance undeterminableRhea 79715

a ganglioside Ac-O-8-GD2(d18:1(4E)) = a ganglioside Ac-O-9-GD2(d18:1(4E))

Direction not assertedBalance undeterminableRhea 79719

1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol hexakisphosphate + phosphate + H(+)

Direction not assertedBalancedRhea 79723

sungeidine F + 3'-phosphoadenylyl sulfate = sulfosungeidine F + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 79727

sulfosungeidine F = sungeidine A + sulfate + H(+)

Direction not assertedBalancedRhea 79731

sungeidine E + 3'-phosphoadenylyl sulfate = sulfosungeidine E + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalancedRhea 79735

a ganglioside GD1b + UDP-alpha-D-galactose = a ganglioside Gal-GD1b + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79739

a ganglioside GD1b (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside Gal-GD1b (d18:1(4E)) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79743

a ganglioside Gal-GD1b + UDP-alpha-D-galactose = a ganglioside GalGal-GD1b + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79747

a ganglioside Gal-GD1b (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GalGal-GD1b (d18:1(4E)) + UDP + H(+)

Direction not assertedBalance undeterminableRhea 79751

a ganglioside Gal-GD1b + GDP-beta-L-fucose = a ganglioside Gal(Fuc)-GD1b + GDP + H(+)

Direction not assertedBalance undeterminableRhea 79755

a ganglioside Gal-GD1b (d18:1(4E)) + GDP-beta-L-fucose = a ganglioside Gal(Fuc)-GD1b (d18:1(4E)) + GDP + H(+)

Direction not assertedBalance undeterminableRhea 79759

a ganglioside GT3 (d18:1(4E)) + acetyl-CoA = a ganglioside Ac-O-7-GT3(d18:1(4E)) + CoA

Direction not assertedBalance undeterminableRhea 79763

a ganglioside Ac-O-7-GT3(d18:1(4E)) = a ganglioside Ac-O-8-GT3(d18:1(4E))

Direction not assertedBalance undeterminableRhea 79767

a ganglioside GD1a + acetyl-CoA = a ganglioside Ac-O-7-GD1a + CoA

Direction not assertedBalance undeterminableRhea 79771

a ganglioside GD1a (d18:1(4E)) + acetyl-CoA = a ganglioside Ac-O-7-GD1a (d18:1(4E)) + CoA

Direction not assertedBalance undeterminableRhea 79775

a ganglioside Ac-O-7-GD1a = a ganglioside Ac-O-8-GD1a

Direction not assertedBalance undeterminableRhea 79779

a ganglioside Ac-O-7-GD1a (d18:1(4E)) = a ganglioside Ac-O-8-GD1a (d18:1(4E))

Direction not assertedBalance undeterminableRhea 79783

a ganglioside Ac-O-8-GD1a = a ganglioside Ac-O-9-GD1a

Direction not assertedBalance undeterminableRhea 79787

a ganglioside Ac-O-8-GD1a (d18:1(4E)) = a ganglioside Ac-O-9-GD1a (d18:1(4E))

Direction not assertedBalance undeterminableRhea 79791

a ganglioside GT1a + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b + CMP + H(+)

Direction not assertedBalance undeterminableRhea 79795

a ganglioside GT1a (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GQ1b (d18:1(4E)) + CMP + H(+)

Direction not assertedBalance undeterminableRhea 79799

a ganglioside GD1alpha (d18:1(4E)) + CMP-N-acetyl-beta-neuraminate = a ganglioside GT1aalpha (d18:1(4E)) + CMP + H(+)

Direction not assertedBalance undeterminableRhea 79803

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