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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

16,551–16,600 of 18,558 reactions from Rhea

(3R)-hydroxyoctadecanoyl-CoA + NAD(+) = 3-oxooctadecanoyl-CoA + NADH + H(+)
Direction not assertedBalancedRhea 78607
15-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 15,20-dihydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 78611
L-lysine + ATP + H(+) = L-lysyl-5'-AMP + diphosphate
Direction not assertedBalancedRhea 78615
L-lysyl-5'-AMP + tRNA(Lys) = L-lysyl-tRNA(Lys) + AMP + H(+)
Direction not assertedBalancedRhea 78619
L-lysyl-5'-AMP + ATP = P(1),P(4)-bis(5'-adenosyl) tetraphosphate + L-lysine
Direction not assertedBalancedRhea 78623
S-sulfanyl-L-cysteine + L-cysteine = S-disulfanyl-L-cysteine + L-alanine
Left to rightBalancedRhea 78627

hexacosanoyl-CoA + O2 = (2E)-hexacosenoyl-CoA + H2O2

Left to rightBalancedRhea 78631

3-oxohexacosanoyl-CoA + NADH + H(+) = (3R)-hydroxyhexacosanoyl-CoA + NAD(+)

Right to leftBalancedRhea 78635

tetracosanoyl-CoA + acetyl-CoA = 3-oxohexacosanoyl-CoA + CoA

Direction not assertedBalancedRhea 78639

(3R)-hydroxytetradecanoyl-CoA = (2E)-tetradecenoyl-CoA + H2O

Direction not assertedBalancedRhea 78643

S-sulfanyl-L-cysteine + tRNA(Cys) + ATP = (S)-sulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate

Left to rightBalancedRhea 78647

S-disulfanyl-L-cysteine + tRNA(Cys) + ATP = (S)-disulfanyl-L-cysteinyl-tRNA(Cys) + AMP + diphosphate

Left to rightBalancedRhea 78651

(2E,6E)-farnesyl diphosphate = silphinene + diphosphate

Direction not assertedBalancedRhea 78655

silphinene-15-oate + 2 reduced [NADPH--hemoprotein reductase] + 2 O2 = gamma-lactone-2-keto[5.5.5.5]fenestrane + 2 oxidized [NADPH--hemoprotein reductase] + 3 H2O + H(+)

Direction not assertedBalance undeterminableRhea 78659

gamma-lactone-2-keto[5.5.5.5]fenestrane + NADPH + O2 + H(+) = penifulvin A + NADP(+) + H2O

Direction not assertedBalancedRhea 78663

(3R)-hydroxytetradecanoyl-CoA + NAD(+) = 3-oxotetradecanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78667

(3R)-3-hydroxydodecanoyl-CoA + NAD(+) = 3-oxododecanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78671

silphinene + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = silphinene-15-oate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 78675

Sr(2+)(in) = Sr(2+)(out)

Direction not assertedBalancedTransportRhea 78679

a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end phospho-ribonucleoside in mRNA + diphosphate + H(+)

Left to rightBalance undeterminableRhea 78683

adenylyl-molybdopterin + molybdate + H(+) = adenylyl MoO3-molybdopterin cofactor + H2O

Direction not assertedBalancedRhea 78687

a D-glucoside + [(1->2)-beta-D-glucosyl](n) = a beta-D-glucosyl-(1->2)-D-glucoside + [(1->2)-beta-D-glucosyl](n-1)

Direction not assertedBalance undeterminableRhea 78691

a ganglioside GA2 + UDP-alpha-D-galactose = a ganglioside GA1 + UDP + H(+)

Direction not assertedBalance undeterminableRhea 78695

a 3-O-beta-D-glucosyl-beta-D-glucuronoside + phosphate = a beta-D-glucuronoside + alpha-D-glucose 1-phosphate

Direction not assertedBalance undeterminableRhea 78699

4-(hydroxy(methyl)phosphoryl)-2-oxobutanoate + L-glutamate = L-phosphinothricin + 2-oxoglutarate

Direction not assertedBalancedRhea 78703

an N-terminal L-arginyl-L-aminoacyl-[protein] + H2O = an N-terminal L-alpha-aminoacyl-[protein] + L-arginine

Direction not assertedBalance undeterminableRhea 78707

3-O-beta-D-glucosyl-D-glucuronate + phosphate = aldehydo-D-glucuronate + alpha-D-glucose 1-phosphate

Direction not assertedBalancedRhea 78711

3-dehydro-alpha-D-glucosyl beta-D-fructofuranoside + H2O = 3-dehydro-D-glucose + D-fructose

Direction not assertedBalancedRhea 78715

3-dehydro-alpha,alpha-trehalose + H2O = 3-dehydro-D-glucose + D-glucose

Direction not assertedBalancedRhea 78719

3'-dehydromaltose + H2O = 3-dehydro-D-glucose + D-glucose

Direction not assertedBalancedRhea 78723

(3S)-hydroxydocosanoyl-CoA + NAD(+) = 3-oxodocosanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78727

(3S)-hydroxyeicosanoyl-CoA + NAD(+) = 3-oxoeicosanoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 78731

(3S)-hydroxytetracosanoyl-CoA + NAD(+) = 3-oxotetracosanoyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 78735

(3S)-hydroxyoctadecanoyl-CoA + NAD(+) = 3-oxooctadecanoyl-CoA + NADH + H(+)

Left to rightBalancedRhea 78739

ipecoside + H2O = ipecoside aglycone + D-glucose

Direction not assertedBalancedRhea 78743

an alpha-L-rhamnosyl-(1->4)-beta-D-glucuronide = a 4-deoxy-alpha-L-threo-hex-4-enopyranuronoside + L-rhamnopyranose

Direction not assertedBalance undeterminableRhea 78747

a fatty acyl-CoA + (R)-carnitine = a fatty acyl-L-carnitine + CoA

Direction not assertedBalance undeterminableRhea 78751

alpha-L-rhamnosyl-(1->4)-D-glucuronate = 4-deoxy-L-threo-hex-4-enopyranuronate + L-rhamnopyranose

Direction not assertedBalancedRhea 78755

L-isoleucyl-[protein] + AH2 + 2 S-adenosyl-L-methionine = methylcyclopropylglycine-[protein] + 2 5'-deoxyadenosine + 2 L-methionine + A + 2 H(+)

Direction not assertedBalance undeterminableRhea 78759

deacetylipecoside + H2O = deacetylipecoside aglycone + D-glucose

Direction not assertedBalancedRhea 78763

3''-dehydroorientin = 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin

Direction not assertedBalancedRhea 78767

3''-dehydroisoorientin = 1,5-anhydro-D-erythro-hex-1-en-3-ulose + luteolin

Direction not assertedBalancedRhea 78771

3''-dehydroisovitexin = 1,5-anhydro-D-erythro-hex-1-en-3-ulose + apigenin

Direction not assertedBalancedRhea 78775

L-arginine + 2 H2O + 2 H(+) = L-ornithine + 2 NH4(+) + CO2

Direction not assertedBalancedRhea 78779

luteolin + UDP-alpha-D-glucose = isoorientin + UDP + H(+)

Direction not assertedBalancedRhea 78783

apigenin + UDP-alpha-D-glucose = isovitexin + UDP + H(+)

Direction not assertedBalancedRhea 78787

D-cysteine + O2 + H2O = 2-oxo-3-sulfanylpropanoate + H2O2 + NH4(+)

Left to rightBalancedRhea 78791

a 3-oxoacyl-[ACP] + acetyl-[ACP] + H2O = a 3-carboxymethyl-3-hydroxy-acyl-[ACP] + holo-[ACP] + H(+)

Direction not assertedBalance undeterminableRhea 78795

a D-alpha-amino acid + O2 = a 2-iminocarboxylate + H2O2

Direction not assertedBalance undeterminableRhea 78799

a 2-iminocarboxylate + H2O = a 2-oxocarboxylate + NH4(+)

Direction not assertedBalance undeterminableRhea 78803

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