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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

1,601–1,650 of 18,558 reactions from Rhea

deoxycholate + FAD + H2O + H(+) = cholate + FADH2
Direction not assertedBalancedRhea 16717
5,10-methylenetetrahydromethanopterin + oxidized coenzyme F420-(gamma-L-Glu)(n) + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420-(gamma-L-Glu)(n)
Direction not assertedBalance undeterminableRhea 16721
a phosphatidylglycerol phosphate + H2O = a phosphatidylglycerol + phosphate
Direction not assertedBalance undeterminableRhea 16725
(1R,2R)-1,2-dihydrobenzene-1,2-diol + NADP(+) = catechol + NADPH + H(+)
Direction not assertedBalancedRhea 16729
orsellinate + H(+) = orcinol + CO2
Direction not assertedBalancedRhea 16733
toluene + NADH + O2 + H(+) = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+)
Direction not assertedBalancedRhea 16737

a 2-acylglycerol + an acyl-CoA = a 1,2-diacylglycerol + CoA

Left to rightBalance undeterminableRhea 16741

phylloquinone + AH2 + O2 = 2,3-epoxyphylloquinone + A + H2O

Direction not assertedBalancedRhea 16745

phosphonoacetate + H2O = acetate + phosphate + H(+)

Direction not assertedBalancedRhea 16749

Mg-13(1)-oxoprotoporphyrin 13-monomethyl ester + NADPH + O2 = 3,8-divinyl protochlorophyllide a + NADP(+) + 2 H2O

Direction not assertedBalancedRhea 16753

trypanothione + NADP(+) = trypanothione disulfide + NADPH + H(+)

Direction not assertedBalancedRhea 16757

chlorohydroquinone + O2 = 5-chlorocarbonyl-4-hydroxy-penta-2,4-dienoate + H(+)

Direction not assertedBalancedRhea 16761

D-mannitol + NADP(+) = D-fructose + NADPH + H(+)

Direction not assertedBalancedRhea 16765

(2R)-3-phospho-glyceroyl phosphate + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + (2R)-3-phosphoglycerate + H(+)

Left to rightBalancedRhea 16769

a ganglioside GM2 (d18:1(4E)) + UDP-alpha-D-galactose = a ganglioside GM1 (d18:1(4E)) + UDP + H(+)

Left to rightBalance undeterminableRhea 16773

K(+)(out) + ATP + H2O = K(+)(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 16777

a fatty acyl-CoA + H2O = a fatty acid + CoA + H(+)

Left to rightBalance undeterminableRhea 16781

an adenosine in tRNA + S-adenosyl-L-methionine = an N(6)-methyladenosine in tRNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 16785

a (2S)-2-hydroxycarboxylate + O2 = a 2-oxocarboxylate + H2O2

Left to rightBalance undeterminableRhea 16789

N-[(R)-4-phosphopantothenoyl]-L-cysteine + H(+) = (R)-4'-phosphopantetheine + CO2

Left to rightBalancedRhea 16793

L-tyrosyl-[protein] + 3'-phosphoadenylyl sulfate = O-sulfo-L-tyrosine-[protein] + adenosine 3',5'-bisphosphate + H(+)

Direction not assertedBalance undeterminableRhea 16801

deacetoxycephalosporin C + 2-oxoglutarate + O2 = deacetylcephalosporin C + succinate + CO2

Direction not assertedBalancedRhea 16805

(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate

Direction not assertedBalancedRhea 16809

L-kynurenine + H2O = anthranilate + L-alanine + H(+)

Direction not assertedBalancedRhea 16813

6-phospho-D-gluconate + NADP(+) = 6-phospho-2-dehydro-D-gluconate + NADPH + H(+)

Direction not assertedBalancedRhea 16817

6-phospho-D-gluconate + NAD(+) = 6-phospho-2-dehydro-D-gluconate + NADH + H(+)

Direction not assertedBalancedRhea 16821

uridine + ATP = UMP + ADP + H(+)

Direction not assertedBalancedRhea 16825

an aldehyde + O2 + H2O = a carboxylate + H2O2 + H(+)

Direction not assertedBalance undeterminableRhea 16829

2 glutathione + H2O2 = glutathione disulfide + 2 H2O

Left to rightBalancedRhea 16833

a 5'-acylphosphoadenosine + H2O = a carboxylate + AMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 16837

precorrin-2 + S-adenosyl-L-methionine = precorrin-3A + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 16841

oxaloacetate + acetyl-CoA + H2O = citrate + CoA + H(+)

Direction not assertedBalancedRhea 16845

N(6)-(1,2-dicarboxyethyl)-AMP = fumarate + AMP

Direction not assertedBalancedRhea 16853

a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-methyl-2'-deoxycytidine in DNA + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 16857

(8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine = S-adenosyl-4-methylsulfanyl-2-oxobutanoate + (7R,8S)-7,8-diammoniononanoate

Direction not assertedBalancedRhea 16861

choloyl-CoA + propanoyl-CoA = 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + CoA

Right to leftBalancedRhea 16865

(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate

Left to rightBalancedRhea 16869

uridine(54) in tRNA + (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADH + H(+) = 5-methyluridine(54) in tRNA + (6S)-5,6,7,8-tetrahydrofolate + NAD(+)

Direction not assertedBalancedRhea 16873

3-sulfino-L-alanine + H(+) = hypotaurine + CO2

Direction not assertedBalancedRhea 16877

thiosulfate + hydrogen cyanide = thiocyanate + sulfite + 2 H(+)

Direction not assertedBalancedRhea 16881

2 (4E,15E)-bilirubin IXalpha C8-beta-D-glucuronoside = bilirubin IXalpha bis-beta-D-glucuronoside + (4Z,15Z)-bilirubin IXalpha

Direction not assertedBalancedRhea 16885

6-acetamido-3-aminohexanoate + 2-oxoglutarate = 6-acetamido-3-oxohexanoate + L-glutamate

Direction not assertedBalancedRhea 16889

pyridine + S-adenosyl-L-methionine = N-methylpyridinium + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 16893

a 3beta-hydroxysteroid + a triacylglycerol = a 3beta-hydroxysteroid ester + a diacylglycerol

Direction not assertedBalance undeterminableRhea 16897

L-2,4-diaminobutanoate + acetyl-CoA = (2S)-4-acetamido-2-aminobutanoate + CoA + H(+)

Direction not assertedBalancedRhea 16901

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + H2O = a 2,3-saturated aldehyde + sn-glycero-3-phosphoethanolamine

Direction not assertedBalance undeterminableRhea 16905

2 Fe(III)-[cytochrome c] + glycine + H2O = 2 Fe(II)-[cytochrome c] + glyoxylate + NH4(+) + 2 H(+)

Direction not assertedBalance undeterminableRhea 16909

a CDP-1,2-diacyl-sn-glycerol + L-serine = a 1,2-diacyl-sn-glycero-3-phospho-L-serine + CMP + H(+)

Direction not assertedBalance undeterminableRhea 16913

2,6-dihydroxypyridine + NADH + O2 + H(+) = 2,3,6-trihydroxypyridine + NAD(+) + H2O

Direction not assertedBalancedRhea 16917

N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = N(4)-{beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 16921

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