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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

16,401–16,450 of 18,558 reactions from Rhea

2 UTP = 2',3'-c-di-UMP + 2 diphosphate
Direction not assertedBalancedRhea 78003
a 1,2-diacyl-3-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphing-4-enine = an N-(omega-(9Z,12Z-octadecadienoyloxy)-ultra-long chain fatty acyl)-sphing-4-enine + a 1,2-diacylglycerol
Direction not assertedBalance undeterminableRhea 78007
a 1,3-diacyl-2-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphing-4-enine = an N-(omega-(9Z,12Z-octadecadienoyloxy)-ultra-long chain fatty acyl)-sphing-4-enine + a 1,3-diacylglycerol
Direction not assertedBalance undeterminableRhea 78011
a 1,2-diacylglycerol + H2O = a 2-acylglycerol + a fatty acid + H(+)
Direction not assertedBalance undeterminableRhea 78015
a 1,3-diacylglycerol + H2O = a 1-acylglycerol + a fatty acid + H(+)
Left to rightBalance undeterminableRhea 78019
a 1-O-alkyl-2-acetyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine

? Direction not asserted

Balance undeterminable

Rhea 78023

a 1-O-alkyl-2-acetyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + a 1-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 78027

a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 78031

a 3-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,3-diacyl-sn-glycerol + a 2-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 78035

1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-3-acylglycerol + a 1-acyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 78039

1-O-alkylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-3-acylglycerol + a 2-acyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 78043

1-O-alkyl-2-acetylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-2-acetyl-3-acylglycerol + a 2-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 78047

1-O-alkyl-2-acetylglycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-alkyl-2-acetyl-3-acylglycerol + a 1-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 78051

an N-acylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 2-(acylamino)ethyl fatty acid + a 2-acyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 78055

an N-acylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 2-(acylamino)ethyl fatty acid + a 1-acyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 78059

a triacylglycerol + all-trans-retinol = an all-trans-retinyl ester + a 1,2-diacylglycerol

Direction not assertedBalance undeterminableRhea 78063

a triacylglycerol + all-trans-retinol = an all-trans-retinyl ester + a 1,3-diacylglycerol

Direction not assertedBalance undeterminableRhea 78067

a 2-acyl-sn-glycerol 3-phosphate + H2O = a 2-acylglycerol + phosphate

Direction not assertedBalance undeterminableRhea 78071

a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = a 2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 78075

a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = a 1-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 78079

a 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O = 1-acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 78083

a 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + H2O = 2-acyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 78087

Fe(II)-heme b-[protein] + nitric oxide + O2 = Fe(III)-heme b-[protein] + nitrate

Left to rightBalance undeterminableRhea 78091

a 2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 78095

a 1-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + H2O = 3-beta-D-galactosyl-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 78099

sn-glycerol 3-phosphocholine + an acyl-CoA = a 2-acyl-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalance undeterminableRhea 78103

sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-acyl-sn-glycero-3-phosphoethanolamine + CoA

Direction not assertedBalance undeterminableRhea 78107

sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 2-acyl-sn-glycero-3-phosphoethanolamine + CoA

Direction not assertedBalance undeterminableRhea 78111

a 1,2-diacyl-3-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base = an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base + a 1,2-diacylglycerol

Direction not assertedBalance undeterminableRhea 78115

a 1,3-diacyl-2-(9Z,12Z-octadecadienoyl)-glycerol + an N-(omega-hydroxy-ultra-long chain fatty acyl)-sphingoid base = an N-[omega-(9Z,12Z-octadecadienoyloxy)-O-ultra-long chain fatty acyl]-sphingoid base + a 1,3-diacylglycerol

Direction not assertedBalance undeterminableRhea 78119

a 2-acyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 2-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 78127

a 3-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,3-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 78131

a 3-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,3-diacylglycerol + a 2-acyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 78135

a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,3-diacylglycerol + a 2-acyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 78139

a 1-acyl-sn-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a 1,3-diacylglycerol + a 1-acyl-sn-glycero-3-phosphocholine

Left to rightBalance undeterminableRhea 78143

a 1,3-diacylglycerol + H2O = a 1-acyl-sn-glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 78147

a 3-acyl-sn-glycerol + H2O = glycerol + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 78151

RNA(n)-3'-guanine ribonucleotide = 2',3'-cyclophospho-GMP + RNA(n)

Direction not assertedBalance undeterminableRhea 78155

RNA(n)-3'-adenine ribonucleotide = 2',3'-cyclophospho-AMP + RNA(n)

Direction not assertedBalance undeterminableRhea 78159

a 2-acyl-sn-glycero-3-phosphocholine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = a 1-acyl-sn-glycero-3-phosphoethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 78163

2-epi-5-epi-valiolone + NAD(+) = demethylgadusol + NADH + 2 H(+)

Direction not assertedBalancedRhea 78167

demethylgadusol + S-adenosyl-L-methionine = gadusol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 78171

all-trans-retinol + a 1,2-diacyl-sn-glycero-3-phosphocholine = an all-trans-retinyl ester + a 2-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 78175

a 1,3-diacylglycerol + an acyl-CoA = a triacylglycerol + CoA

Direction not assertedBalance undeterminableRhea 78179

a 1,2-diacylglycerol + an acyl-CoA = a triacylglycerol + CoA

Direction not assertedBalance undeterminableRhea 78183

a 1-acyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine = sn-glycero-3-phosphoethanolamine + a 1-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 78187

a 1-acyl-sn-glycero-3-phosphoethanolamine + sn-glycerol 3-phosphocholine = sn-glycero-3-phosphoethanolamine + a 2-acyl-sn-glycero-3-phosphocholine

Direction not assertedBalance undeterminableRhea 78191

a 3beta-hydroxysteroid + a triacylglycerol = a 3beta-hydroxysteroid ester + a 1,2-diacylglycerol

Direction not assertedBalance undeterminableRhea 78195

a 3beta-hydroxysteroid + a triacylglycerol = a 3beta-hydroxysteroid ester + a 1,3-diacylglycerol

Direction not assertedBalance undeterminableRhea 78199

D-valine + O2 + H2O = 3-methyl-2-oxobutanoate + H2O2 + NH4(+)

Left to rightBalancedRhea 78203

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