Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

16,051–16,100 of 18,558 reactions from Rhea

(12Z)-10-hydroxyoctadecenoate + H2O = 10,13-dihydroxyoctadecanoate
Direction not assertedBalancedRhea 76603
(9Z,12Z,15Z)-octadecatrienoate + H2O = (12Z,15Z)-10-hydroxyoctadecadienoate
Direction not assertedBalancedRhea 76607
vanillin + NADPH + H(+) = 4-hydroxy-3-methoxy-benzenemethanol + NADP(+)
Direction not assertedBalancedRhea 76611
3-oxopropanoate + NAD(+) + CoA + H2O = hydrogencarbonate + acetyl-CoA + NADH + H(+)
Left to rightBalancedRhea 76615
(6E)-8-methylnon-6-enoyl-CoA + 4-hydroxy-3-methoxy-benzenemethanol = capsiate + CoA
Direction not assertedBalancedRhea 76619
(R)-2-methyl-3-oxopropanoate + NAD(+) + CoA + H2O = propanoyl-CoA + hydrogencarbonate + NADH + H(+)
Left to rightBalancedRhea 76623
(S)-2-methyl-3-oxopropanoate + NAD(+) + CoA + H2O = propanoyl-CoA + hydrogencarbonate + NADH + H(+)

Left to rightBalancedRhea 76627

Ca(2+)(in) + n H(+)(out) = Ca(2+)(out) + n H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 76631

Mn(2+)(in) + n H(+)(out) = Mn(2+)(out) + n H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 76635

cytosine(out) = cytosine(in)

Direction not assertedBalancedTransportRhea 76639

xanthine(out) = xanthine(in)

Direction not assertedBalancedTransportRhea 76643

(3S)-3-hydroxyadipyl-CoA = (E)-2,3-didehydroadipoyl-CoA + H2O

Direction not assertedBalancedRhea 76647

3-methylbutanal + NADP(+) + H2O = 3-methylbutanoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 76651

3-methylbutanal + NAD(+) + H2O = 3-methylbutanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 76655

butanal + NADP(+) + H2O = butanoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 76659

pentanal + NADP(+) + H2O = pentanoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 76663

furfural + NAD(+) + H2O = 2-furoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 76667

furfural + NADP(+) + H2O = 2-furoate + NADPH + 2 H(+)

Direction not assertedBalancedRhea 76671

1-deoxysphinganine + a fatty acyl-CoA = N-acyl-1-deoxysphinganine + CoA + H(+)

Direction not assertedBalance undeterminableRhea 76675

sulfoacetaldehyde + NAD(+) + CoA = sulfoacetyl-CoA + NADH + H(+)

Direction not assertedBalancedRhea 76679

sulfoacetate + ATP + CoA = sulfoacetyl-CoA + ADP + phosphate

Direction not assertedBalancedRhea 76683

(9S)-hydroperoxy-(10E,12Z)-octadecadienoate + 2 glutathione = (9S)-hydroxy-(10E,12Z)-octadecadienoate + glutathione disulfide + H2O

Left to rightBalancedRhea 76687

(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + 2 glutathione = (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + glutathione disulfide + H2O

Left to rightBalancedRhea 76691

(15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + 2 glutathione = (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + glutathione disulfide + H2O

Left to rightBalancedRhea 76695

(5S)-hydroperoxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + 2 glutathione = (5S)-hydroxy-(6E,8Z,11Z,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O

Left to rightBalancedRhea 76699

(12S)-hydroperoxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + 2 glutathione = (12S)-hydroxy-(5Z,8Z,10E,14Z,17Z)-eicosapentaenoate + glutathione disulfide + H2O

Left to rightBalancedRhea 76703

(15S)-hydroperoxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + 2 glutathione = (15S)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + glutathione disulfide + H2O

Left to rightBalancedRhea 76707

(15S)-hydroperoxy-(11Z,13E)-eicosadienoate + 2 glutathione = (15S)-hydroxy-(11Z,13E)-eicosadienoate + glutathione disulfide + H2O

Left to rightBalancedRhea 76711

(17S)-hydroperoxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + 2 glutathione = (17S)-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + glutathione disulfide + H2O

Left to rightBalancedRhea 76715

dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 3-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76719

dodecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 5-hydroxydodecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76723

tetradecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 7-hydroxytetradecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76727

a hydroperoxy-1,2-diacyl-glycero-3-phosphocholine + 2 glutathione = a hydroxy-1,2-diacyl-glycero-3-phosphocholine + glutathione disulfide + H2O

Left to rightBalance undeterminableRhea 76731

decane + reduced [NADPH--hemoprotein reductase] + O2 = 3-decanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76735

dodecane + reduced [NADPH--hemoprotein reductase] + O2 = 5-dodecanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76739

tetradecane + reduced [NADPH--hemoprotein reductase] + O2 = 7-tetradecanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76743

hexadecane + reduced [NADPH--hemoprotein reductase] + O2 = 9-hexadecanol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76747

5-hydroxydodecanoate + H(+) = delta-dodecalactone + H2O

Direction not assertedBalancedRhea 76751

decan-1-ol + reduced [NADPH--hemoprotein reductase] + O2 = 1,3-decanediol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76755

dodecan-1-ol + reduced [NADPH--hemoprotein reductase] + O2 = 1,5-dodecanediol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76759

dodecan-1-ol + reduced [NADPH--hemoprotein reductase] + O2 = 1,4-dodecanediol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76763

emodin + S-adenosyl-L-methionine = physcion + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 76767

dodecan-1-ol + reduced [NADPH--hemoprotein reductase] + O2 = 1,3-dodecanediol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76771

decan-1-ol + reduced [NADPH--hemoprotein reductase] + O2 = 1,7-decanediol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76775

dodecan-1-ol + reduced [NADPH--hemoprotein reductase] + O2 = 1,6-dodecanediol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76779

dodecan-1-ol + reduced [NADPH--hemoprotein reductase] + O2 = 1,9-dodecanediol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76783

dodecan-1-ol + reduced [NADPH--hemoprotein reductase] + O2 = 1,10-dodecanediol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 76787

hexadecanoate + reduced [NADPH--hemoprotein reductase] + O2 = 9-hydroxyhexadecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 76791

2-aminopropan-1-ol + NAD(+) + H2O = hydroxyacetone + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 76795

(2S)-2-aminobutan-1-ol + NAD(+) + H2O = 1-hydroxy-2-butanone + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 76799

Page 322 of 372