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CompoundsSubstances with curated findings
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

15,851–15,900 of 18,558 reactions from Rhea

pyruvate(out) + Na(+)(out) = pyruvate(in) + Na(+)(in)
Direction not assertedBalancedTransportRhea 75799
butanoate(out) + Na(+)(out) = butanoate(in) + Na(+)(in)
Direction not assertedBalancedTransportRhea 75803
propanoate(out) + Na(+)(out) = propanoate(in) + Na(+)(in)
Direction not assertedBalancedTransportRhea 75807
acetoacetate(out) + Na(+)(out) = acetoacetate(in) + Na(+)(in)
Direction not assertedBalancedTransportRhea 75811
K(+)(in) + ATP + H2O = K(+)(out) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 75815
(5Z,8Z)-octadecadienoate + O2 = (5S)-hydroperoxy-(6E,8Z)-octadecadienoate
Direction not assertedBalancedRhea 75819
(5S)-hydroxy-(6E,8Z)-octadecadienoate + reduced [NADH--hemoprotein reductase] + O2 = 5-oxo-(6E,8Z)-octadecadienoate + oxidized [NADH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 75823

(5S)-hydroxy-(6E,8Z)-octadecadienoate + reduced [NADH--hemoprotein reductase] + O2 = (5S,18)-dihydroxy-(6E,8Z)-octadecadienoate + oxidized [NADH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 75827

5-oxo-(6E,8Z)-octadecadienoate + reduced [NADH--hemoprotein reductase] + O2 = 5-oxo-18-hydroxy-(6E,8Z)-octadecadienoate + oxidized [NADH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 75831

(5S)-hydroperoxy-(6E,8Z)-octadecadienoate + 2 glutathione = (5S)-hydroxy-(6E,8Z)-octadecadienoate + glutathione disulfide + H2O

Direction not assertedBalancedRhea 75835

serotonin(out) + K(+)(in) + Na(+)(out) + H(+)(in) = serotonin(in) + K(+)(out) + Na(+)(in) + H(+)(out)

Left to rightBalancedTransportRhea 75839

ergothioneine(out) + Na(+)(out) = ergothioneine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 75843

9-cis-retinoate + reduced [NADPH--hemoprotein reductase] + O2 = 9-cis-4-hydroxyretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 75847

all-trans-4-hydroxyretinoate + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-4-oxoretinoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Left to rightBalance undeterminableRhea 75851

9-cis-4-hydroxyretinoate + reduced [NADPH--hemoprotein reductase] + O2 = 9-cis-4-oxoretinoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Left to rightBalance undeterminableRhea 75855

all-trans-4-hydroxy-13,14-dihydroretinoate + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-4-oxo-13,14-dihydroretinoate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Left to rightBalance undeterminableRhea 75859

all-trans-13,14-dihydroretinoate + reduced [NADPH--hemoprotein reductase] + O2 = all-trans-4-hydroxy-13,14-dihydroretinoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 75863

5,6,7,8-tetrahydromethanopterin + methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] = 5-methyl-5,6,7,8-tetrahydromethanopterin + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+)

Direction not assertedBalance undeterminableRhea 75867

methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] + (6S)-5,6,7,8-tetrahydrofolate = Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + (6S)-5-methyl-5,6,7,8-tetrahydrofolate + H(+)

Direction not assertedBalance undeterminableRhea 75871

methyl-Co(III)-[quaternary-amine-specific corrinoid protein] + (6S)-5,6,7,8-tetrahydrofolate = Co(I)-[quaternary-amine-specific corrinoid protein] + (6S)-5-methyl-5,6,7,8-tetrahydrofolate + H(+)

Direction not assertedBalance undeterminableRhea 75875

Co(I)-[quaternary-amine-specific corrinoid protein] + L-proline betaine + H(+) = methyl-Co(III)-[quaternary-amine-specific corrinoid protein] + N-methyl-L-proline

Direction not assertedBalance undeterminableRhea 75879

NAD(+) = ADP-1-deoxy-1,O(4)-didehydro-D-ribose + nicotinamide

Direction not assertedBalancedRhea 75883

ADP-1-deoxy-1,O(4)-didehydro-D-ribose + L-arginyl-[protein] = ADP-riboxanated L-argininyl-[protein] + NH4(+) + H(+)

Direction not assertedBalance undeterminableRhea 75887

pseudomonoyl-CoA C + holothin = pseudomonic acid C--holothin + CoA

Direction not assertedBalancedRhea 75891

marinoloyl-CoA C + holothin = thiomarinol C + CoA

Direction not assertedBalancedRhea 75895

1,2-diacyl-sn-glycero-3-phospho-N-acyl-L-serine + H2O = 1-acyl-sn-glycero-3-phospho-N-acyl-L-serine + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 75899

ADP-D-glycero-beta-D-manno-heptose + L-seryl-[protein] = O-(D-glycero-alpha-D-manno-heptosyl)-L-seryl-[protein] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 75903

ADP-L-glycero-beta-D-manno-heptose + L-seryl-[protein] = O-(L-glycero-alpha-D-manno-heptosyl)-L-seryl-[protein] + ADP + H(+)

Direction not assertedBalance undeterminableRhea 75907

N-acyl-1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + H2O = N-acyl-1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + a fatty acid + H(+)

Direction not assertedBalance undeterminableRhea 75911

serinol + NAD(+) + H2O = dihydroxyacetone + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 75915

serinol + NADP(+) + H2O = dihydroxyacetone + NH4(+) + NADPH + H(+)

Direction not assertedBalancedRhea 75919

(S)-4-aminopentanoate + NAD(+) + H2O = 4-oxopentanoate + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 75923

cyclohexylamine + NAD(+) + H2O = cyclohexanone + NH4(+) + NADH + H(+)

Direction not assertedBalancedRhea 75927

taurocyamine + H2O = urea + taurine

Left to rightBalancedRhea 75931

N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine + ATP = 6-O-phospho-N-acetyl-D-muramoyl-L-alanyl-D-isoglutamine + ADP + H(+)

Left to rightBalancedRhea 75935

4-aminobutanoate + L-arginine = 4-guanidinobutanoate + L-ornithine

Left to rightBalancedRhea 75939

beta-alanine + L-arginine = 3-guanidinopropanoate + L-ornithine

Left to rightBalancedRhea 75943

taurine + L-arginine = taurocyamine + L-ornithine

Left to rightBalancedRhea 75947

oripavine + 2-oxoglutarate + O2 = neomorphinone + formaldehyde + succinate + CO2

Direction not assertedBalancedRhea 75951

thebaine + 2-oxoglutarate + O2 = oripavine + formaldehyde + succinate + CO2

Direction not assertedBalancedRhea 75955

(S)-scoulerine + 2-oxoglutarate + O2 = (S)-3-O-demethylscoulerine + formaldehyde + succinate + CO2

Direction not assertedBalancedRhea 75959

15-deoxy-Delta(12,14)-prostaglandin J2 + glutathione = 15-deoxy-Delta(12,14)-prostaglandin J2-S-(R)-glutathione

Left to rightBalancedRhea 75963

(6-hydroxyhexanoyl)(n) + H2O = (6-hydroxyhexanoyl)(n-1) + 6-hydroxyhexanoate + H(+)

Direction not assertedBalance undeterminableRhea 75967

neomorphine + NADP(+) = neomorphinone + NADPH + H(+)

Direction not assertedBalancedRhea 75971

(S)-stylopine + S-adenosyl-L-methionine = (S)-cis-N-methylstylopine + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 75975

argipressin(out) = argipressin(in)

Left to rightBalancedTransportRhea 75979

(indol-3-yl)acetate(out) + a dicarboxylate(in) = (indol-3-yl)acetate(in) + a dicarboxylate(out)

Direction not assertedBalance undeterminableTransportRhea 75983

indoxyl sulfate(out) + a dicarboxylate(in) = indoxyl sulfate(in) + a dicarboxylate(out)

Direction not assertedBalance undeterminableTransportRhea 75987

N-benzoylglycine(out) + a dicarboxylate(in) = N-benzoylglycine(in) + a dicarboxylate(out)

Direction not assertedBalance undeterminableTransportRhea 75991

3-carboxy-4-methyl-5-propyl-2-furanpropanoate(out) + a dicarboxylate(in) = 3-carboxy-4-methyl-5-propyl-2-furanpropanoate(in) + a dicarboxylate(out)

Direction not assertedBalance undeterminableTransportRhea 75995

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