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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

15,751–15,800 of 18,558 reactions from Rhea

queuosine 5'-phosphate + H2O = queuine + D-ribose 5-phosphate
Left to rightBalancedRhea 75387
N(alpha)-formyl-L-methionyl-L-leucyl-L-phenylalanine(out) + 2 H(+)(out) = N(alpha)-formyl-L-methionyl-L-leucyl-L-phenylalanine(in) + 2 H(+)(in)
Direction not assertedBalancedTransportRhea 75399
propane-1,3-diamine + pyruvate = 3-aminopropanal + L-alanine
Direction not assertedBalancedRhea 75403
2-dehydro-D-glucose = cortalcerone + H2O
Direction not assertedBalancedRhea 75407
demethyllactenocin + S-adenosyl-L-methionine = lactenocin + S-adenosyl-L-homocysteine + H(+)
Direction not assertedBalancedRhea 75411
N-methylmyosmine + H2O = pseudooxynicotine
Direction not assertedBalancedRhea 75415
(R,S)-butane-2,3-diol + NAD(+) = (S)-acetoin + NADH + H(+)

Direction not assertedBalancedRhea 75419

(R,S)-butane-2,3-diol + NAD(+) = (R)-acetoin + NADH + H(+)

Direction not assertedBalancedRhea 75423

eburicol + reduced [NADPH--hemoprotein reductase] + O2 = 32-hydroxyeburicol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 75427

32-hydroxyeburicol + reduced [NADPH--hemoprotein reductase] + O2 = 32-oxoeburicol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 75431

32-oxoeburicol + reduced [NADPH--hemoprotein reductase] + O2 = 14-demethyleburicol + formate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 75435

eburicol + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = 14-demethyleburicol + formate + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 75439

heme b(in) = heme b(out)

Direction not assertedBalancedTransportRhea 75443

(9Z,12Z)-octadecadienoate + AH2 + O2 = (9R)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O

Left to rightBalancedRhea 75447

(9Z,12Z)-octadecadienoate + AH2 + O2 = (13S)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O

Left to rightBalancedRhea 75451

(9Z,12Z)-octadecadienoate + AH2 + O2 = (13R)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O

Left to rightBalancedRhea 75455

(9Z,12Z)-octadecadienoate + AH2 + O2 = (9S)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O

Left to rightBalancedRhea 75459

choline(out) + n H(+)(in) = choline(in) + n H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 75463

ethanolamine(out) + n H(+)(in) = ethanolamine(in) + n H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 75467

thiamine diphosphate(out) = thiamine diphosphate(in)

Direction not assertedBalancedTransportRhea 75471

D-mannose(out) + n Na(+)(out) = D-mannose(in) + n Na(+)(in)

Direction not assertedBalance undeterminableTransportRhea 75475

S-adenosyl-L-homocysteine(out) + S-adenosyl-L-methionine(in) = S-adenosyl-L-homocysteine(in) + S-adenosyl-L-methionine(out)

Direction not assertedBalancedTransportRhea 75479

estrone 3-sulfate(out) + n H(+)(out) = estrone 3-sulfate(in) + n H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 75483

dehydroepiandrosterone 3-sulfate(out) + n H(+)(out) = dehydroepiandrosterone 3-sulfate(in) + n H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 75487

25-hydroxyvitamin D3 sulfate(out) + n H(+)(out) = 25-hydroxyvitamin D3 sulfate(in) + n H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 75491

pregnenolone sulfate(out) + n H(+)(out) = pregnenolone sulfate(in) + n H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 75495

cholate(out) + n H(+)(out) = cholate(in) + n H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 75499

glycocholate(out) + n H(+)(out) = glycocholate(in) + n H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 75503

taurocholate(out) + n H(+)(out) = taurocholate(in) + n H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 75507

S-benzyl-L-cysteine + acetyl-CoA = N-acetyl-S-benzyl-L-cysteine + CoA + H(+)

Direction not assertedBalancedRhea 75511

N-acetyl-L-cysteine + H2O = L-cysteine + acetate

Direction not assertedBalancedRhea 75515

N-acetyl-S-benzyl-L-cysteine + FMNH2 + O2 = (R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMN + H2O + H(+)

Direction not assertedBalancedRhea 75519

S-methyl-L-cysteine + acetyl-CoA = N-acetyl-S-methyl-L-cysteine + CoA + H(+)

Direction not assertedBalancedRhea 75523

(R)-N-acetyl-S-benzyl-L-cysteine sulfoxide + FMNH2 + O2 = N-acetyl-S-hydroxy-L-cysteine + benzaldehyde + FMN + H2O + H(+)

Direction not assertedBalancedRhea 75527

N-acetyl-S-hydroxy-L-cysteine + AH2 = N-acetyl-L-cysteine + A + H2O

Direction not assertedBalancedRhea 75531

N-acetyl-S-methyl-L-cysteine + FMNH2 + O2 = (R)-N-acetyl-S-methyl-L-cysteine sulfoxide + FMN + H2O + H(+)

Direction not assertedBalancedRhea 75535

(2E)-decenoate + holo-[ACP] + ATP = (2E)-decenoyl-[ACP] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 75539

(3R)-3-[(carboxylmethyl)amino]decanoate + holo-[ACP] + H(+) = (2E)-decenoyl-[ACP] + glycine + H2O

Direction not assertedBalance undeterminableRhea 75543

2 (3R)-3-isocyanylbutanoyl-[ACP] + L-lysine + ATP + 2 NADPH = (2S)-2,6-bis[(3R)-3-isocyanobutanamido]hexan-1-ol + 2 holo-[ACP] + AMP + diphosphate + 2 NADP(+)

Direction not assertedBalance undeterminableRhea 75547

2 a (3R)-3-isocyanyl-fatty acyl-[ACP] + L-lysine + ATP + 2 NADPH = an isonitrile lipopeptide + 2 holo-[ACP] + AMP + diphosphate + 2 NADP(+)

Direction not assertedBalance undeterminableRhea 75551

(-)-cyatha-3,12-diene + reduced [NADPH--hemoprotein reductase] + O2 = erinacol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 75555

erinacol + reduced [NADPH--hemoprotein reductase] + O2 = cyathadiol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 75559

cyathadiol + reduced [NADPH--hemoprotein reductase] + O2 = cyathatriol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 75563

cyathatriol + acetyl-CoA = 11-O-acetylcyathatriol + CoA

Direction not assertedBalancedRhea 75567

cyathin A3 + acetyl-CoA = 11-O-acetylcyathin A3 + CoA

Direction not assertedBalancedRhea 75571

11-O-acetylcyathatriol + A = 11-O-acetylcyathin A3 + AH2

Direction not assertedBalancedRhea 75575

cyathatriol + A = cyathin A3 + AH2

Direction not assertedBalancedRhea 75579

11-O-acetylcyathatriol + UDP-alpha-D-xylose = erinacine Q + UDP + H(+)

Direction not assertedBalancedRhea 75583

11-O-acetylcyathatriol + UDP-alpha-D-glucose = erinacine Q2 + UDP + H(+)

Direction not assertedBalancedRhea 75587

(9S)-hydroperoxy-(10E,12Z)-octadecadienoate = (11S)-hydroxy-(9S,10S)-epoxy-(12Z)-octadecenoate

Direction not assertedBalancedRhea 75591

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