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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

15,701–15,750 of 18,558 reactions from Rhea

2,5-dihydroxybenzoyl-CoA + H2O = 2,5-dihydroxybenzoate + CoA + H(+)
Direction not assertedBalancedRhea 75187
2-dehydro-3-deoxy-L-fuconate + NAD(+) = 2,4-didehydro-3-deoxy-L-rhamnonate + NADH + H(+)
Direction not assertedBalancedRhea 75191
2-dehydro-3-deoxy-D-arabinonate + NAD(+) = 5-hydroxy-2,4-dioxopentanoate + NADH + H(+)
Direction not assertedBalancedRhea 75195
triuret + H2O = 1-carboxybiuret + NH4(+)
Direction not assertedBalancedRhea 75199
alpha,alpha-trehalose(out) + ATP + H2O = alpha,alpha-trehalose(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 75203
Ag(+)(out) = Ag(+)(in)
Direction not assertedBalancedTransportRhea 75207
Cu(+)(out) = Cu(+)(in)

Direction not assertedBalancedTransportRhea 75211

beta-L-fucose + NADP(+) = L-fucono-1,5-lactone + NADPH + H(+)

Direction not assertedBalancedRhea 75215

L-fucono-1,5-lactone + H2O = L-fuconate + H(+)

Direction not assertedBalancedRhea 75219

L-fucono-1,4-lactone + H2O = L-fuconate + H(+)

Direction not assertedBalancedRhea 75223

L-xylono-1,4-lactone + H2O = L-xylonate + H(+)

Direction not assertedBalancedRhea 75227

L-galactono-1,4-lactone + H2O = L-galactonate + H(+)

Direction not assertedBalancedRhea 75231

L-fucono-1,5-lactone = L-fucono-1,4-lactone

Direction not assertedBalancedRhea 75235

N-terminal L-methionyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-methionyl-[protein] + CoA + H(+)

Direction not assertedBalance undeterminableRhea 75239

N-terminal L-leucyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-leucyl-[protein] + CoA + H(+)

Direction not assertedBalance undeterminableRhea 75243

N-terminal L-prolyl-[protein] + acetyl-CoA = N-terminal N(alpha)-acetyl-L-prolyl-[protein] + CoA + H(+)

Direction not assertedBalance undeterminableRhea 75247

carminate + O2 = 3'-dehydrocarminate + H2O2

Direction not assertedBalancedRhea 75251

mangiferin + O2 = 3'-dehydromangiferin + H2O2

Direction not assertedBalancedRhea 75255

isoorientin + O2 = 3''-dehydroisoorientin + H2O2

Direction not assertedBalancedRhea 75259

isovitexin + O2 = 3''-dehydroisovitexin + H2O2

Direction not assertedBalancedRhea 75263

D-arabinose + NADP(+) = D-arabinono-1,5-lactone + NADPH + H(+)

Direction not assertedBalancedRhea 75267

serotonin + S-adenosyl-L-methionine = 5-methoxytryptamine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 75271

(9S)-hydroperoxy-(10E,12Z)-octadecadienoate = (10R,11R)-epoxy-(9S)-hydroxy-(12Z)-octadecenoate

Direction not assertedBalancedRhea 75275

an omega-methyl-medium-chain fatty acid + reduced [NADPH--hemoprotein reductase] + O2 = an omega-hydroxy-medium-chain fatty acid + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 75279

decanoate + reduced [NADPH--hemoprotein reductase] + O2 = 10-hydroxydecanoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 75283

glyoxylate(in) + sulfate(out) = glyoxylate(out) + sulfate(in)

Direction not assertedBalancedTransportRhea 75287

oxalate(out) + glyoxylate(in) = oxalate(in) + glyoxylate(out)

Direction not assertedBalancedTransportRhea 75291

sulfate(out) + chloride(in) = sulfate(in) + chloride(out)

Direction not assertedBalancedTransportRhea 75295

NAD(+) = 2'cADPR + nicotinamide + H(+)

Direction not assertedBalancedRhea 75299

NAD(+) = 3'cADPR + nicotinamide + H(+)

Direction not assertedBalancedRhea 75303

D-serine(in) + L-glutamine(out) + Na(+)(out) = D-serine(out) + L-glutamine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 75307

D-serine(in) + L-alanine(out) + Na(+)(out) = D-serine(out) + L-alanine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 75311

D-serine(out) + chloride(out) + 2 Na(+)(out) = D-serine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 75315

D-alanine(out) + chloride(out) + 2 Na(+)(out) = D-alanine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 75319

D-leucine(out) + chloride(out) + 2 Na(+)(out) = D-leucine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 75323

D-tryptophan(out) + chloride(out) + 2 Na(+)(out) = D-tryptophan(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 75327

D-methionine(out) + chloride(out) + 2 Na(+)(out) = D-methionine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 75331

bromide(in) + chloride(out) = bromide(out) + chloride(in)

Direction not assertedBalancedTransportRhea 75335

nitrate(in) + chloride(out) = nitrate(out) + chloride(in)

Direction not assertedBalancedTransportRhea 75339

adenosine(in) = adenosine(out)

ReversibleBalancedTransportRhea 75343

thiocyanate(in) = thiocyanate(out)

Direction not assertedBalancedTransportRhea 75347

pseudooxynicotine + 2 Fe(III)-[cytochrome c] + H2O = 4-oxo-4-(pyridin-3-yl)butanal + methylamine + 2 Fe(II)-[cytochrome c] + 2 H(+)

Direction not assertedBalance undeterminableRhea 75351

L-mimosine + H2O = 3-hydroxy-4H-pyrid-4-one + pyruvate + NH4(+)

Direction not assertedBalancedRhea 75355

L-mimosine = 3-hydroxy-4H-pyrid-4-one + 2-aminoprop-2-enoate

Direction not assertedBalancedRhea 75359

thymidine(in) = thymidine(out)

ReversibleBalancedTransportRhea 75363

cytidine(in) = cytidine(out)

ReversibleBalancedTransportRhea 75367

guanosine(in) = guanosine(out)

ReversibleBalancedTransportRhea 75371

inosine(in) = inosine(out)

ReversibleBalancedTransportRhea 75375

L-canavanine + H2O = N-hydroxyguanidine + L-homoserine

Direction not assertedBalancedRhea 75379

bromide(in) = bromide(out)

Direction not assertedBalancedTransportRhea 75383

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