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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Outcomes
Proteins
Interactions
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Chemistry

Reactions
Reach

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Cell types
Organisms
Materials
Assessments
Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

15,651–15,700 of 18,558 reactions from Rhea

erythrostominone(in) = erythrostominone(out)
Direction not assertedBalancedTransportRhea 74987
deoxyerythrostominone(in) = deoxyerythrostominone(out)
Direction not assertedBalancedTransportRhea 74991
epierythrostominol(in) = epierythrostominol(out)
Direction not assertedBalancedTransportRhea 74995
deoxyerythrostominol(in) = deoxyerythrostominol(out)
Direction not assertedBalancedTransportRhea 74999
sulfoacetate + ATP + CoA = sulfoacetyl-CoA + AMP + diphosphate
Direction not assertedBalancedRhea 75003
VO(2+)(out) + H(+)(out) = VO(2+)(in) + H(+)(in)
Direction not assertedBalancedTransportRhea 75007
1,2,3-tri-(9Z-octadecenoyl)-glycerol + 9-hydroxy-octadecanoate = 9-(9Z-octadecenoyloxy)-octadecanoate + 2,3-di-(9Z)-octadecenoyl-sn-glycerol

Direction not assertedBalancedRhea 75011

1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-hydroxy-octadecanoate = 9-hexadecanoyloxy-octadecanoate + 2,3-di-(9Z)-octadecenoyl-sn-glycerol

Direction not assertedBalancedRhea 75015

1,2,3-tri-(10Z)-heptadecenoylglycerol + 9-hydroxy-octadecanoate = 2,3-di-(10Z-heptadecenoyl)-sn-glycerol + 9-(10Z-heptadecenoyloxy)-octadecanoate

Direction not assertedBalancedRhea 75019

1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol + 9-hydroxy-octadecanoate = 2,3-di-(9Z,12Z)-octadecadienoyl-sn-glycerol + 9-(9Z,12Z-octadecadienoyloxy)-octadecanoate

Direction not assertedBalancedRhea 75023

1,2,3-tri-(9Z)-hexadecenoylglycerol + 9-hydroxy-octadecanoate = 2,3-di-(9Z)-hexadecenoyl-sn-glycerol + 9-(9Z-hexadecenoyloxy)-octadecanoate

Direction not assertedBalancedRhea 75027

9-hydroxy-octadecanoate + 1,2-di-(9Z-octadecenoyl)-sn-glycerol = 9-(9Z-octadecenoyloxy)-octadecanoate + 2-(9Z-octadecenoyl)-glycerol

Direction not assertedBalancedRhea 75031

1-hexadecanoyl-2,3-di-(9Z)-octadecenoyl-sn-glycerol + 9-hydroxy-octadecanoate = 1-hexadecanoyl-3-(9Z)-octadecenoyl-sn-glycerol + 9-(9Z-octadecenoyloxy)-octadecanoate

Direction not assertedBalancedRhea 75035

acetyl-CoA(in) = acetyl-CoA(out)

Left to rightBalancedTransportRhea 75039

L-cystine(out) + L-leucine(in) = L-cystine(in) + L-leucine(out)

Direction not assertedBalancedTransportRhea 75043

N(omega),N(omega)-dimethyl-L-arginine(out) = N(omega),N(omega)-dimethyl-L-arginine(in)

Direction not assertedBalancedTransportRhea 75047

chenodeoxycholate(out) = chenodeoxycholate(in)

Direction not assertedBalancedTransportRhea 75051

(E)-caffeate + H(+) = 3,4-dihydroxystyrene + CO2

Direction not assertedBalancedRhea 75055

K(+)(in) + 2 hydrogencarbonate(in) + chloride(out) = K(+)(out) + 2 hydrogencarbonate(out) + chloride(in)

Direction not assertedBalancedTransportRhea 75059

Li(+)(in) + 2 hydrogencarbonate(in) + chloride(out) = Li(+)(out) + 2 hydrogencarbonate(out) + chloride(in)

Direction not assertedBalancedTransportRhea 75063

Rb(+)(in) + 2 hydrogencarbonate(in) + chloride(out) = Rb(+)(out) + 2 hydrogencarbonate(out) + chloride(in)

Direction not assertedBalancedTransportRhea 75067

Cs(+)(in) + 2 hydrogencarbonate(in) + chloride(out) = Cs(+)(out) + 2 hydrogencarbonate(out) + chloride(in)

Direction not assertedBalancedTransportRhea 75071

dihydro-6-demethylsterigmatocystin + S-adenosyl-L-methionine = dihydrosterigmatocystin + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 75075

24,25-dihydrolanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 32-hydroxy-24,25-dihydrolanosterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 75079

32-oxo-24,25-dihydrolanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 4,4-dimethyl-8,14-cholestadien-3beta-ol + formate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Left to rightBalance undeterminableRhea 75083

32-hydroxy-24,25-dihydrolanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 32-oxo-24,25-dihydrolanosterol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Left to rightBalance undeterminableRhea 75087

sulfate(out) + 2 chloride(in) = sulfate(in) + 2 chloride(out)

Direction not assertedBalancedTransportRhea 75091

oxalate(out) + 2 chloride(in) = oxalate(in) + 2 chloride(out)

Direction not assertedBalancedTransportRhea 75095

(4Z,15Z)-bilirubin IXalpha + UDP-alpha-D-glucuronate = (4Z,15Z)-bilirubin IXalpha C12-beta-D-glucuronoside + UDP

Left to rightBalancedRhea 75099

lanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 32-hydroxylanosterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Left to rightBalance undeterminableRhea 75103

32-hydroxylanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 32-oxolanosterol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Left to rightBalance undeterminableRhea 75107

32-oxolanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 4,4-dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + formate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Left to rightBalance undeterminableRhea 75111

all-trans-13,14-dihydroretinol + NAD(+) = all-trans-13,14-dihydroretinal + NADH + H(+)

Direction not assertedBalancedRhea 75115

all-trans-13,14-dihydroretinal + NAD(+) + H2O = all-trans-13,14-dihydroretinoate + NADH + 2 H(+)

Left to rightBalancedRhea 75119

(1R)-(1-hydroxyethyl)phosphonate + O2 = acetate + phosphate + 2 H(+)

Direction not assertedBalancedRhea 75123

neopinone = codeinone

Direction not assertedBalancedRhea 75127

neomorphinone = morphinone

Direction not assertedBalancedRhea 75131

neopine + NADP(+) = neopinone + NADPH + H(+)

Direction not assertedBalancedRhea 75135

4-hydroxyprotoasukamycin + NADH + O2 + H(+) = asukamycin + NAD(+) + H2O

Direction not assertedBalancedRhea 75139

prosolanapyrone III = solanapyrone D

Direction not assertedBalancedRhea 75143

(2E,6E,10E)-geranylgeranyl diphosphate = (-)-cyatha-3,12-diene + diphosphate

Direction not assertedBalancedRhea 75147

(2E,6E,10E)-geranylgeranyl diphosphate + H2O = neoverrucosan-5beta-ol + diphosphate

Direction not assertedBalancedRhea 75151

(2E,6E,10E)-geranylgeranyl diphosphate + H2O = verrucosan-2beta-ol + diphosphate

Direction not assertedBalancedRhea 75155

5-methyl-UTP + NAD(+) = 5-methyl-UDP + NADP(+) + H(+)

Direction not assertedBalancedRhea 75159

UTP + NAD(+) = UDP + NADP(+) + H(+)

Direction not assertedBalancedRhea 75163

CTP + NAD(+) = CDP + NADP(+) + H(+)

Direction not assertedBalancedRhea 75167

GTP + NAD(+) = GDP + NADP(+) + H(+)

Direction not assertedBalancedRhea 75171

dATP + NAD(+) = dADP + NADP(+) + H(+)

Direction not assertedBalancedRhea 75175

(2E,6E,10E)-geranylgeranyl diphosphate = (R)-axinyssene + diphosphate

Direction not assertedBalancedRhea 75179

(2E,6E,10E)-geranylgeranyl diphosphate = lydicene + diphosphate

Direction not assertedBalancedRhea 75183

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