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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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Reference

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

15,601–15,650 of 18,558 reactions from Rhea

L-histidyl-L-proline diketopiperazine(in) = L-histidyl-L-proline diketopiperazine(out)
Direction not assertedBalancedTransportRhea 74787
(R)-salsolinol(in) = (R)-salsolinol(out)
Direction not assertedBalancedTransportRhea 74791
N-methyl-(R)-salsolinol(in) = N-methyl-(R)-salsolinol(out)
Direction not assertedBalancedTransportRhea 74795
2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Direction not assertedBalancedRhea 74799
2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA
Direction not assertedBalancedRhea 74803
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
Direction not asserted

?

Balanced

Rhea 74807

2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 74811

2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA

Direction not assertedBalancedRhea 74815

glutathione(in) = glutathione(out)

Direction not assertedBalancedTransportRhea 74819

2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA

Direction not assertedBalancedRhea 74823

UDP-alpha-D-galacturonate(in) + UMP(out) = UDP-alpha-D-galacturonate(out) + UMP(in)

Direction not assertedBalancedTransportRhea 74827

UDP-alpha-D-xylose(in) + UDP-alpha-D-glucuronate(out) = UDP-alpha-D-xylose(out) + UDP-alpha-D-glucuronate(in)

Left to rightBalancedTransportRhea 74831

UDP-N-acetyl-alpha-D-galactosamine(in) + UDP-alpha-D-glucuronate(out) = UDP-N-acetyl-alpha-D-galactosamine(out) + UDP-alpha-D-glucuronate(in)

Left to rightBalancedTransportRhea 74835

UDP-alpha-D-glucuronate(out) + UDP(in) = UDP-alpha-D-glucuronate(in) + UDP(out)

Direction not assertedBalancedTransportRhea 74839

a ganglioside GM1b + 3'-phosphoadenylyl sulfate = an 8-O-sulfo-ganglioside GM1b + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalance undeterminableRhea 74843

1D-myo-inositol 1,2,3,4,5-pentakisphosphate + ATP = 3-diphospho-1D-myo-inositol 1,2,4,5-tetrakisphosphate + ADP

Direction not assertedBalancedRhea 74847

dopamine + acetaldehyde = (R)-salsolinol + H2O

Direction not assertedBalancedRhea 74851

dopamine + pyruvate = (R)-salsolinol-1-carboxylate + H2O

Direction not assertedBalancedRhea 74855

dopamine + formaldehyde = norsalsolinol + H2O

Direction not assertedBalancedRhea 74859

(R)-salsolinol + S-adenosyl-L-methionine = N-methyl-(R)-salsolinol + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 74863

(E)-caffeyl aldehyde + NADP(+) + CoA = (E)-caffeoyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 74867

(E)-cinnamate + S-adenosyl-L-methionine = (E)-cinnamic acid methyl ester + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 74871

3-phenylpropanoate + S-adenosyl-L-methionine = 3-phenylpropanoic acid methyl ester + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 74875

(E)-4-coumarate + S-adenosyl-L-methionine = (E)-4-coumaric acid methyl ester + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 74879

phloretate + S-adenosyl-L-methionine = 3-(4-hydroxyphenyl)propionic acid methyl ether + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 74883

2',3'-cGAMP(in) + ATP + H2O = 2',3'-cGAMP(out) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 74887

CO2(out) = CO2(in)

Left to rightBalancedTransportRhea 74891

nitric oxide(out) = nitric oxide(in)

Direction not assertedBalancedTransportRhea 74895

(2E)-2-butenoate + holo-[ACP] + ATP = (2E)-butenoyl-[ACP] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 74899

(2E)-2-butenoate + ATP + H(+) = (2E)-but-2-enoyl-AMP + diphosphate

Direction not assertedBalancedRhea 74903

(2E)-but-2-enoyl-AMP + holo-[ACP] = (2E)-butenoyl-[ACP] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 74907

a (2E)-enoyl fatty acid + holo-[ACP] + ATP = a (2E)-enoyl-[ACP] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 74911

a (2E)-enoyl fatty acid + ATP + H(+) = a (2E)-2-fatty-enoyl-AMP + diphosphate

Direction not assertedBalance undeterminableRhea 74915

a (2E)-2-fatty-enoyl-AMP + holo-[ACP] = a (2E)-enoyl-[ACP] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 74919

a (3R)-3-[(carboxymethyl)amino]fatty acid + holo-[ACP] + H(+) = a (2E)-enoyl-[ACP] + glycine + H2O

Direction not assertedBalance undeterminableRhea 74923

(3R)-3-[(carboxymethyl)amino]butanoate + holo-[ACP] + H(+) = (2E)-butenoyl-[ACP] + glycine + H2O

Direction not assertedBalance undeterminableRhea 74927

a (3R)-3-[(carboxymethyl)amino]fatty acid + 2 2-oxoglutarate + 2 O2 = a (3R)-3-isocyanyl-fatty acid + 2 succinate + 3 CO2 + 2 H2O

Direction not assertedBalance undeterminableRhea 74931

(3R)-3-[(carboxymethyl)amino]butanoate + 2 2-oxoglutarate + 2 O2 = (3R)-3-isocyanylbutanoate + 2 succinate + 3 CO2 + 2 H2O

Direction not assertedBalancedRhea 74935

a (3R)-3-[(carboxymethyl)amino]fatty acid + 2-oxoglutarate + O2 = a (3R)-3-{[carboxy(hydroxy)methyl]amino}fatty acid + succinate + CO2

Direction not assertedBalance undeterminableRhea 74939

a (3R)-3-{[carboxy(hydroxy)methyl]amino}fatty acid + 2-oxoglutarate + O2 = a (3R)-3-isocyanyl-fatty acid + succinate + 2 CO2 + 2 H2O

Direction not assertedBalance undeterminableRhea 74943

(3R)-3-[(carboxymethyl)amino]butanoate + 2-oxoglutarate + O2 = (3R)-3-{[carboxy(hydroxy)methyl]amino}butanoate + succinate + CO2

Direction not assertedBalancedRhea 74947

(3R)-3-{[carboxy(hydroxy)methyl]amino}butanoate + 2-oxoglutarate + O2 = (3R)-3-isocyanylbutanoate + succinate + 2 CO2 + 2 H2O

Direction not assertedBalancedRhea 74951

a (3R)-3-isocyanyl-fatty acid + holo-[ACP] + ATP = a (3R)-3-isocyanyl-fatty acyl-[ACP] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 74955

(3R)-3-isocyanylbutanoate + holo-[ACP] + ATP = (3R)-3-isocyanylbutanoyl-[ACP] + AMP + diphosphate

Direction not assertedBalance undeterminableRhea 74959

L-ornithine(in) + L-leucine(out) + Na(+)(out) = L-ornithine(out) + L-leucine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 74963

a (3R)-3-isocyanyl-fatty acid + ATP + H(+) = a (3R)-3-isocyanyl-fatty acyl-AMP + diphosphate

Direction not assertedBalance undeterminableRhea 74967

L-lysine(in) + L-leucine(out) + Na(+)(out) = L-lysine(out) + L-leucine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 74971

a (3R)-3-isocyanyl-fatty acyl-AMP + holo-[ACP] = a (3R)-3-isocyanyl-fatty acyl-[ACP] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 74975

(3R)-3-isocyanylbutanoate + ATP + H(+) = (3R)-3-isocyanylbutanoyl-AMP + diphosphate

Direction not assertedBalancedRhea 74979

(3R)-3-isocyanylbutanoyl-AMP + holo-[ACP] = (3R)-3-isocyanylbutanoyl-[ACP] + AMP + H(+)

Direction not assertedBalance undeterminableRhea 74983

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