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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

15,501–15,550 of 18,558 reactions from Rhea

formamide(out) = formamide(in)
Direction not assertedBalancedTransportRhea 74387
methylamine(out) = methylamine(in)
Left to rightBalancedTransportRhea 74391
prostaglandin E1(out) + 2 (S)-lactate(in) = prostaglandin E1(in) + 2 (S)-lactate(out)
Direction not assertedBalancedTransportRhea 74395
prostaglandin F2alpha(out) + 2 (S)-lactate(in) = prostaglandin F2alpha(in) + 2 (S)-lactate(out)
Direction not assertedBalancedTransportRhea 74399
prostaglandin D2(out) + 2 (S)-lactate(in) = prostaglandin D2(in) + 2 (S)-lactate(out)
Direction not assertedBalancedTransportRhea 74403
thromboxane B2(out) + 2 (S)-lactate(in) = thromboxane B2(in) + 2 (S)-lactate(out)
Direction not assertedBalancedTransportRhea 74407

1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74411

1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) = 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74415

1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + H(+)(out) = 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74419

1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74423

1-hexadecanoyl-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-hexadecanoyl-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74427

1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-(1Z-hexadecenyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74431

a 1-acyl-sn-glycero-3-phosphocholine(out) + H(+)(out) = a 1-acyl-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 74435

a 1-acyl-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) = a 1-acyl-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 74439

1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(out) + H(+)(out) = 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)(in) + H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 74443

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 74447

1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine(out) + H(+)(out) = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74451

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) = a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)

Direction not assertedBalance undeterminableTransportRhea 74455

1-O-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine(out) + H(+)(out) = 1-O-(1Z-hexadecenyl)-sn-glycero-3-phosphoethanolamine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 74459

(-)-4'-methoxycyclopenine = 4'-methoxyviridicatin + methyl isocyanate + H(+)

Direction not assertedBalancedRhea 74463

a 1-O-alkyl-2-acyl-3-(beta-D-3-sulfogalactosyl)-sn-glycerol + H2O = a 1-O-alkyl-2-acyl-3-O-(beta-D-galactosyl)-sn-glycerol + sulfate + H(+)

Direction not assertedBalance undeterminableRhea 74467

(-)-4'-methoxycyclopeptine + 2-oxoglutarate + O2 = (Z)-4'-methoxydehydrocyclopeptine + succinate + CO2 + H2O

Direction not assertedBalancedRhea 74471

(Z)-4'-methoxydehydrocyclopeptine + 2-oxoglutarate + O2 = (-)-4'-methoxycyclopenine + succinate + CO2

Direction not assertedBalancedRhea 74475

(-)-cyclopeptine + 2-oxoglutarate + O2 = (Z)-dehydrocyclopeptine + succinate + CO2 + H2O

Direction not assertedBalancedRhea 74479

(Z)-dehydrocyclopeptine + 2-oxoglutarate + O2 = (-)-cyclopenine + succinate + CO2

Direction not assertedBalancedRhea 74483

O-methyl-L-tyrosine + anthranilate + S-adenosyl-L-methionine + 2 ATP = (-)-4'-methoxycyclopeptine + 2 AMP + S-adenosyl-L-homocysteine + 2 diphosphate + 2 H(+)

Direction not assertedBalancedRhea 74487

[(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B = yaequinolone D

Direction not assertedBalancedRhea 74491

[(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B = yaequinolone C

Direction not assertedBalancedRhea 74495

yaequinolone D + NADPH + H(+) = penigequinolone A + NADP(+) + H2O

Direction not assertedBalancedRhea 74499

yaequinolone D + NADPH + H(+) = penigequinolone B + NADP(+) + H2O

Direction not assertedBalancedRhea 74503

[(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B = (1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B + H2O

Direction not assertedBalancedRhea 74507

(1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B = aspoquinolone A

Direction not assertedBalancedRhea 74511

(1'E,3'E)-5-(3,3-dimethyloxiran-2-yl)-3-methylhexa-1,3-dienyl-quinolinone B = aspoquinolone B

Direction not assertedBalancedRhea 74515

1-(3-O-sulfo-beta-D-galactosyl)-ceramide + H2O = a beta-D-Gal-(1<->1')-ceramide + sulfate + H(+)

Direction not assertedBalance undeterminableRhea 74519

L-lysine + 2 S-adenosyl-L-methionine = N(6),N(6)-dimethyl-L-lysine + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 74523

N(6),N(6)-dimethyl-L-lysine + H(+) = N,N-dimethyl-cadaverine + CO2

Direction not assertedBalancedRhea 74527

archaetidylglycerol + AH2 + 2 S-adenosyl-L-methionine = macrocyclic archaetidylglycerol + 2 5'-deoxyadenosine + 2 L-methionine + A + 2 H(+)

Direction not assertedBalancedRhea 74531

2 archaetidylglycerol + 2 AH2 + 4 S-adenosyl-L-methionine = glycerol dibiphytanyl glycerol tetraether glycerophospholipid + 4 5'-deoxyadenosine + 4 L-methionine + 2 A + 4 H(+)

Direction not assertedBalancedRhea 74535

creatinine(in) = creatinine(out)

Direction not assertedBalancedTransportRhea 74539

(2E,6E,10E)-geranylgeranyl diphosphate = (E,E,E)-alpha-springene + diphosphate

Direction not assertedBalancedRhea 74543

(2E,6E,10E)-geranylgeranyl diphosphate = talarodiene + diphosphate

Direction not assertedBalancedRhea 74547

L-seryl-tRNA(Ser) + H2O = tRNA(Ser) + L-serine

Direction not assertedBalancedRhea 74551

(S)-malate(out) = (S)-malate(in)

Direction not assertedBalancedTransportRhea 74555

aldosterone = aldosterone hemiacetal

Direction not assertedBalancedRhea 74559

aldosterone hemiacetal + UDP-alpha-D-glucuronate = aldosterone hemiacetal 18-beta-glucuronide + UDP + H(+)

Direction not assertedBalancedRhea 74563

N-acetyl-L-cysteine(out) + L-glutamate(in) = N-acetyl-L-cysteine(in) + L-glutamate(out)

Direction not assertedBalancedTransportRhea 74567

N-terminal N(alpha)-acetyl-L-methionyl-L-aspartyl-[protein] + H2O = N-terminal L-aspartyl-[protein] + N-acetyl-L-methionine

Left to rightBalance undeterminableRhea 74571

N-terminal N(alpha)-acetyl-L-methionyl-L-glutamyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + N-acetyl-L-methionine

Left to rightBalance undeterminableRhea 74575

N-terminal N(alpha)-acetyl-L-cysteinyl-L-aspartyl-[protein] + H2O = N-terminal L-aspartyl-[protein] + N-acetyl-L-cysteine

Left to rightBalance undeterminableRhea 74579

N-terminal N(alpha)-acetyl-L-cysteinyl-L-glutamyl-[protein] + H2O = N-terminal L-glutamyl-[protein] + N-acetyl-L-cysteine

Left to rightBalance undeterminableRhea 74583

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