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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

15,401–15,450 of 18,558 reactions from Rhea

(2E,6E)-farnesyl diphosphate + H2O = discoidol + diphosphate
Direction not assertedBalancedRhea 73987
geranylgeranyl diphosphate = beta-araneosene + diphosphate
Direction not assertedBalancedRhea 73991
geranylgeranyl diphosphate + H2O = (S)-(+)-nephthenol + diphosphate
Direction not assertedBalancedRhea 73995
quinolinone B + dimethylallyl diphosphate = peniprequinolone + diphosphate
Direction not assertedBalancedRhea 73999
peniprequinolone + A = yaequinolone E + AH2
Direction not assertedBalancedRhea 74003
yaequinolone E + dimethylallyl diphosphate + H2O = [(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + diphosphate
Direction not assertedBalancedRhea 74007
[(1'E)-3'-hydroxy-3',7'-dimethylocta-1',6'-dien-1'-yl]-quinolinone B + NADPH + O2 + H(+) = [(1'E)-5'-(3',3'-dimethyloxiran-2'-yl)-3'-hydroxy-3'-methylpent-1'-en-1'-yl]-quinolinone B + NADP(+) + H2O

Direction not assertedBalancedRhea 74011

4-hydroxybenzoate + phosphate + H(+) = phenyl phosphate + CO2 + H2O

Direction not assertedBalancedRhea 74015

L-alanine(in) + glycine(out) = L-alanine(out) + glycine(in)

Direction not assertedBalancedTransportRhea 74019

L-serine(out) + L-alanine(in) = L-serine(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 74023

L-threonine(out) + L-alanine(in) = L-threonine(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 74027

L-cysteine(out) + L-alanine(in) = L-cysteine(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 74031

D-serine(out) + L-alanine(in) = D-serine(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 74035

D-alanine(out) + L-alanine(in) = D-alanine(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 74039

L-methionine(out) + L-alanine(in) = L-methionine(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 74043

L-valine(out) + L-alanine(in) = L-valine(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 74047

D-threonine(out) + L-alanine(in) = D-threonine(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 74051

D-cysteine(out) + L-alanine(in) = D-cysteine(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 74055

beta-alanine(out) + L-alanine(in) = beta-alanine(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 74059

2-aminoisobutanoate(out) + L-alanine(in) = 2-aminoisobutanoate(in) + L-alanine(out)

Direction not assertedBalancedTransportRhea 74063

an alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A + ADP-L-glycero-beta-D-manno-heptose = an L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)

Direction not assertedBalance undeterminableRhea 74067

an L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP-L-glycero-beta-D-manno-heptose = an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)

Direction not assertedBalance undeterminableRhea 74071

phylloquinone + NADH + H(+) = phylloquinol + NAD(+)

Left to rightBalancedRhea 74075

menaquinone-4 + NADH + H(+) = menaquinol-4 + NAD(+)

Left to rightBalancedRhea 74079

menadiol + (2E,6E,10E)-geranylgeranyl diphosphate = menaquinol-4 + diphosphate

Left to rightBalancedRhea 74083

an L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ATP = an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)

Direction not assertedBalance undeterminableRhea 74087

L-alpha-D-Hep-(1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + ATP = L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + ADP + H(+)

Direction not assertedBalancedRhea 74091

an L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP-L-glycero-beta-D-manno-heptose = an L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A + ADP + H(+)

Direction not assertedBalance undeterminableRhea 74095

L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + ADP-L-glycero-beta-D-manno-heptose = L-alpha-D-Hep-(1->7)-L-alpha-D-Hep-(1->3)-4-O-phospho-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A (E. coli) + ADP + H(+)

Direction not assertedBalancedRhea 74099

1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + H2O = 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + hexadecanoate + H(+)

Left to rightBalancedRhea 74103

discoidol + reduced [NADPH--hemoprotein reductase] + O2 = discodiene + acetone + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 74107

hypotaurine + NADH + O2 + H(+) = taurine + NAD(+) + H2O

Left to rightBalancedRhea 74111

an anthocyanidin + UDP-alpha-D-galactose = an anthocyanidin 3-O-beta-D-galactoside + UDP

Direction not assertedBalance undeterminableRhea 74115

delphinidin + UDP-alpha-D-galactose = delphinidin 3-O-beta-D-galactoside + UDP + H(+)

Direction not assertedBalancedRhea 74119

pelargonidin + UDP-alpha-D-galactose = pelargonidin 3-O-beta-D-galactoside betaine + UDP

Direction not assertedBalancedRhea 74123

peonidin + UDP-alpha-D-galactose = peonidin 3-O-beta-D-galactoside + UDP

Direction not assertedBalancedRhea 74127

malvidin + UDP-alpha-D-galactose = malvidin 3-O-beta-D-galactoside + UDP + H(+)

Direction not assertedBalancedRhea 74131

petunidin + UDP-alpha-D-galactose = petunidin 3-O-beta-D-galactoside + UDP

Direction not assertedBalancedRhea 74135

petunidin + UDP-alpha-D-glucose = petunidin 3-O-beta-D-glucoside + UDP

Direction not assertedBalancedRhea 74139

(2E,6E)-farnesyl diphosphate = (1R,2R)-delta-elemene + diphosphate

Direction not assertedBalancedRhea 74143

(S)-2-benzoylsuccinyl-CoA + CoA = benzoyl-CoA + succinyl-CoA

Direction not assertedBalancedRhea 74147

L-lysyl-[beta-tubulin] + acetyl-CoA = N(6)-acetyl-L-lysyl-[beta-tubulin] + CoA + H(+)

Direction not assertedBalance undeterminableRhea 74151

oxidized 2[4Fe-4S]-[ferredoxin] + sarcosine + H2O = reduced 2[4Fe-4S]-[ferredoxin] + formaldehyde + glycine + 2 H(+)

Direction not assertedBalance undeterminableRhea 74155

1,2-di-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)

Left to rightBalancedRhea 74159

1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + octadecanoate + H(+)

Left to rightBalancedRhea 74163

oxidized 2[4Fe-4S]-[ferredoxin] + N,N-dimethylglycine + H2O = reduced 2[4Fe-4S]-[ferredoxin] + sarcosine + formaldehyde + 2 H(+)

Direction not assertedBalance undeterminableRhea 74167

an N-methyl carbamate ester + H2O + H(+) = an alcohol + methylamine + CO2

Direction not assertedBalance undeterminableRhea 74171

a secondary alkyl amine + NAD(+) + H2O = a ketone + NH4(+) + NADH + H(+)

Direction not assertedBalance undeterminableRhea 74175

a secondary alkyl amine + NADP(+) + H2O = a ketone + NH4(+) + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 74179

taxifolin + S-adenosyl-L-methionine = taxifolin 4'-methyl ether + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 74183

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