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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

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Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

15,251–15,300 of 18,558 reactions from Rhea

malonate(out) + phosphate(in) + H(+)(in) = malonate(in) + phosphate(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 73387
sulfate(out) + phosphate(in) + H(+)(in) = sulfate(in) + phosphate(out) + H(+)(out)
Direction not assertedBalancedTransportRhea 73391
L-aspartate(in) + sulfate(out) = L-aspartate(out) + sulfate(in)
Direction not assertedBalancedTransportRhea 73395
D-aspartate(in) + sulfate(out) = D-aspartate(out) + sulfate(in)
Direction not assertedBalancedTransportRhea 73399
(2R,3R)-tartrate(in) + sulfate(out) = (2R,3R)-tartrate(out) + sulfate(in)
Direction not assertedBalancedTransportRhea 73403
(S,S)-tartrate(in) + sulfate(out) = (S,S)-tartrate(out) + sulfate(in)
Direction not assertedBalancedTransportRhea 73407

sulfate(out) + succinate(in) = sulfate(in) + succinate(out)

Direction not assertedBalancedTransportRhea 73411

(-)-cyclopenine = viridicatin + methyl isocyanate + H(+)

Direction not assertedBalancedRhea 73415

L-glutamine(out) = L-glutamine(in)

ReversibleBalancedTransportRhea 73419

L-asparagine(out) = L-asparagine(in)

Direction not assertedBalancedTransportRhea 73423

genkwanin + reduced [NADPH--hemoprotein reductase] + O2 = scutellarein 7-methyl ether + oxidized [NADPH--hemoprotein reductase] + H2O

Direction not assertedBalance undeterminableRhea 73427

(2S)-sakuranetin + reduced [NADPH--hemoprotein reductase] + O2 = (2S)-7-methylcarthamidin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 73431

apigenin 4',7-dimethyl ether + reduced [NADPH--hemoprotein reductase] + O2 = ladanein + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 73435

(2S)-naringenin 4',7-dimethyl ether + reduced [NADPH--hemoprotein reductase] + O2 = (2S)-carthamidin-4',7-dimethyl ether + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 73439

gardenin B + 2-oxoglutarate + O2 = nevadensin + formaldehyde + succinate + CO2 + H(+)

Direction not assertedBalancedRhea 73443

acetyl-CoA(in) + AMP(out) = acetyl-CoA(out) + AMP(in)

Direction not assertedBalancedTransportRhea 73447

adenosine 3',5'-bisphosphate(in) + AMP(out) = adenosine 3',5'-bisphosphate(out) + AMP(in)

Direction not assertedBalancedTransportRhea 73451

salvigenin + 2 reduced [2Fe-2S]-[ferredoxin] + O2 + 2 H(+) = 8-hydroxysalvigenin + 2 oxidized [2Fe-2S]-[ferredoxin] + H2O

Direction not assertedBalance undeterminableRhea 73455

protochlorophyllide a + 4 reduced [2Fe-2S]-[ferredoxin] + 2 O2 + 5 H(+) = protochlorophyllide b + 4 oxidized [2Fe-2S]-[ferredoxin] + 3 H2O

Direction not assertedBalance undeterminableRhea 73459

carcinine + H2O = histamine + beta-alanine

Direction not assertedBalancedRhea 73463

beta-alanyl-dopamine + H2O = dopamine + beta-alanine

Direction not assertedBalancedRhea 73467

D-ornithine(in) + L-ornithine(out) = D-ornithine(out) + L-ornithine(in)

Direction not assertedBalancedTransportRhea 73471

D-arginine(in) + L-ornithine(out) = D-arginine(out) + L-ornithine(in)

Direction not assertedBalancedTransportRhea 73475

D-histidine(in) + L-ornithine(out) + H(+)(in) = D-histidine(out) + L-ornithine(in) + H(+)(out)

Direction not assertedBalancedTransportRhea 73479

D-lysine(in) + L-ornithine(out) = D-lysine(out) + L-ornithine(in)

Direction not assertedBalancedTransportRhea 73483

orotate(out) + a carboxylate(in) = orotate(in) + a carboxylate(out)

Direction not assertedBalance undeterminableTransportRhea 73487

Co(2+)(out) + 2 hydrogencarbonate(out) = Co(2+)(in) + 2 hydrogencarbonate(in)

Direction not assertedBalancedTransportRhea 73491

an 8-hydroxyflavone + S-adenosyl-L-methionine = an 8-methoxyflavone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalance undeterminableRhea 73495

3',4',7-trihydroxyflavone + S-adenosyl-L-methionine = 4',7-dihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 73499

3',4',7,8-tetrahydroxyflavone + S-adenosyl-L-methionine = 3',4,7-trihydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 73503

7,8-dihydroxyflavone + S-adenosyl-L-methionine = 7-hydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 73507

8-hydroxysalvigenin + 2-oxoglutarate + O2 = pilosin + formaldehyde + succinate + CO2

Direction not assertedBalancedRhea 73511

UTP(in) + UDP(out) = UTP(out) + UDP(in)

Direction not assertedBalancedTransportRhea 73515

dUTP(out) + UTP(in) = dUTP(in) + UTP(out)

Direction not assertedBalancedTransportRhea 73519

5-methyl-UTP(out) + UTP(in) = 5-methyl-UTP(in) + UTP(out)

Direction not assertedBalancedTransportRhea 73523

5-methyl-UDP(out) + UTP(in) = 5-methyl-UDP(in) + UTP(out)

Direction not assertedBalancedTransportRhea 73527

UTP(in) + CTP(out) = UTP(out) + CTP(in)

Direction not assertedBalancedTransportRhea 73531

CDP(out) + UTP(in) = CDP(in) + UTP(out)

Direction not assertedBalancedTransportRhea 73535

dCTP(out) + UTP(in) = dCTP(in) + UTP(out)

Direction not assertedBalancedTransportRhea 73539

dCDP(out) + UTP(in) = dCDP(in) + UTP(out)

Direction not assertedBalancedTransportRhea 73543

UTP(in) + GTP(out) = UTP(out) + GTP(in)

Direction not assertedBalancedTransportRhea 73547

UTP(in) + GDP(out) = UTP(out) + GDP(in)

Direction not assertedBalancedTransportRhea 73551

(E,E)-feruperate + reduced [NADPH--hemoprotein reductase] + O2 = (E,E)-piperate + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 73555

dGTP(out) + UTP(in) = dGTP(in) + UTP(out)

Direction not assertedBalancedTransportRhea 73559

dGDP(out) + UTP(in) = dGDP(in) + UTP(out)

Direction not assertedBalancedTransportRhea 73563

ITP(out) + UTP(in) = ITP(in) + UTP(out)

Direction not assertedBalancedTransportRhea 73567

(E,E)-piperate + ATP + CoA = (E,E)-piperoyl-CoA + AMP + diphosphate

Direction not assertedBalancedRhea 73571

(E,E)-piperate + ATP + H(+) = (E,E)-piperoyl-AMP + diphosphate

Direction not assertedBalancedRhea 73575

(E,E)-piperoyl-AMP + CoA = (E,E)-piperoyl-CoA + AMP + H(+)

Direction not assertedBalancedRhea 73579

CTP(out) + UDP(in) = CTP(in) + UDP(out)

Direction not assertedBalancedTransportRhea 73583

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