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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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Reference

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

15,051–15,100 of 18,558 reactions from Rhea

(22E)-3-oxochola-4,22-dien-24-oyl-CoA + H2O = (22R)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA
Direction not assertedBalancedRhea 72575
(22E)-3-oxochola-4,22-dien-24-oyl-CoA + H2O = (22S)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA
Direction not assertedBalancedRhea 72579
(22S)-hydroxy-3-oxo-chol-4-ene-24-oyl-CoA + NAD(+) = 3,22-dioxochol-4-en-24-oyl-CoA + NADH + H(+)
Direction not assertedBalancedRhea 72583
(E)-sinapate + ATP + CoA = (E)-sinapoyl-CoA + AMP + diphosphate
Direction not assertedBalancedRhea 72587
D-glucuronate(out) + H(+)(out) = D-glucuronate(in) + H(+)(in)
Left to rightBalancedTransportRhea 72591
N-acetyl-L-aspartyl-L-glutamate(out) + H(+)(out) = N-acetyl-L-aspartyl-L-glutamate(in) + H(+)(in)
Direction not assertedBalancedTransportRhea 72595

N-acetyl-L-aspartyl-L-glutamate(out) = N-acetyl-L-aspartyl-L-glutamate(in)

Left to rightBalancedTransportRhea 72599

(E)-sinapate + ATP + H(+) = (E)-sinapoyl-AMP + diphosphate

Direction not assertedBalancedRhea 72603

(E)-sinapoyl-AMP + CoA = (E)-sinapoyl-CoA + AMP + H(+)

Direction not assertedBalancedRhea 72607

L-alanyl-L-lysine(out) + H(+)(out) = L-alanyl-L-lysine(in) + H(+)(in)

Left to rightBalancedTransportRhea 72611

L-alanyl-L-valine(out) + H(+)(out) = L-alanyl-L-valine(in) + H(+)(in)

Left to rightBalancedTransportRhea 72615

2-methoxybenzoate + Co(I)-[methoxylated-aromatic-compound-specific corrinoid protein] + H(+) = methyl-Co(III)-[methoxylated-aromatic-compound-specific corrinoid protein] + salicylate

Direction not assertedBalance undeterminableRhea 72619

N-(2-hydroxy-fatty acyl)-dihydroceramide + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) = inositol-1-phospho-N-(2-hydroxy-fatty acyl)-dihydroceramide + a 1,2-diacyl-sn-glycerol

Direction not assertedBalance undeterminableRhea 72623

Zn(2+)(in) + 2 H(+)(out) = Zn(2+)(out) + 2 H(+)(in)

Direction not assertedBalancedTransportRhea 72627

3 Li(+)(out) + Ca(2+)(in) = 3 Li(+)(in) + Ca(2+)(out)

Direction not assertedBalancedTransportRhea 72631

1-hydroxy-6-methoxyphenazine N(10)-oxide + S-adenosyl-L-methionine = 1,6-dimethoxyphenazine N(5)-oxide + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 72635

1,6-dihydroxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-methionine = 1-hydroxy-6-methoxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 72639

1-hydroxy-6-methoxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-methionine = 1,6-dimethoxyphenazine N(5),N(10)-dioxide + S-adenosyl-L-homocysteine

Direction not assertedBalancedRhea 72643

1,6-dihydroxyphenazine + NADPH + O2 = 1,6-dihydroxyphenazine N(5)-oxide + NADP(+) + H2O

Direction not assertedBalancedRhea 72647

1,6-dihydroxyphenazine N(5)-oxide + NADPH + O2 = 1,6-dihydroxyphenazine N(5),N(10)-dioxide + NADP(+) + H2O

Direction not assertedBalancedRhea 72651

1-hydroxy-6-methoxyphenazine + NADPH + O2 = 1-hydroxy-6-methoxyphenazine N(10)-oxide + NADP(+) + H2O

Direction not assertedBalancedRhea 72655

quinolin-8-ol + NADPH + O2 = 8-hydroxyquinoline N-oxide + NADP(+) + H2O

Direction not assertedBalancedRhea 72659

C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-L-phenylalanyl-[tubulin] + H2O = C-terminal L-alpha-aminoacyl-L-glutamyl-L-glutamyl-[tubulin] + L-phenylalanine

Left to rightBalance undeterminableRhea 72663

secologanin + reduced [NADPH--hemoprotein reductase] + O2 = secoxyloganin + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 72667

6-hydroxyphenazine-1-carboxylate + NADH + O2 + 2 H(+) = 1,6-dihydroxyphenazine + CO2 + NAD(+) + H2O

Direction not assertedBalancedRhea 72671

3',5'-cyclic CMP + H2O = CMP + H(+)

Direction not assertedBalancedRhea 72675

(R)-dihydrolipoate + L-lysyl-[lipoyl-carrier protein] + ATP = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)

Direction not assertedBalance undeterminableRhea 72679

cholate(out) = cholate(in)

Direction not assertedBalancedTransportRhea 72683

all-trans-retinol(out) = all-trans-retinol(in)

Direction not assertedBalancedTransportRhea 72687

17beta-estradiol 17-O-(beta-D-glucuronate)(out) = 17beta-estradiol 17-O-(beta-D-glucuronate)(in)

Left to rightBalancedTransportRhea 72691

UMP(out) + UDP-N-acetyl-alpha-D-glucosamine(in) = UMP(in) + UDP-N-acetyl-alpha-D-glucosamine(out)

Direction not assertedBalancedTransportRhea 72695

acrylate + NADH + H(+) = propanoate + NAD(+)

Direction not assertedBalancedRhea 72699

UMP(out) + UDP-alpha-D-galactose(in) = UMP(in) + UDP-alpha-D-galactose(out)

Direction not assertedBalancedTransportRhea 72703

GMP(out) + GDP-beta-L-fucose(in) = GMP(in) + GDP-beta-L-fucose(out)

Direction not assertedBalancedTransportRhea 72707

cathenamine + H(+) = 4,21-dehydrogeissoschizine

Direction not assertedBalancedRhea 72711

(R)-dihydrolipoate + ATP + H(+) = N(6)-[(R)-dihydrolipoyl]-5'-AMP + diphosphate

Direction not assertedBalancedRhea 72715

N(6)-[(R)-dihydrolipoyl]-5'-AMP + L-lysyl-[lipoyl-carrier protein] = N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + AMP + 2 H(+)

Direction not assertedBalance undeterminableRhea 72719

UDP-alpha-D-xylose(in) + UMP(out) = UDP-alpha-D-xylose(out) + UMP(in)

Direction not assertedBalancedTransportRhea 72723

UMP(out) + UDP-alpha-D-glucuronate(in) = UMP(in) + UDP-alpha-D-glucuronate(out)

Direction not assertedBalancedTransportRhea 72727

UMP(out) + UDP-alpha-D-glucose(in) = UMP(in) + UDP-alpha-D-glucose(out)

Direction not assertedBalancedTransportRhea 72731

UDP-N-acetyl-alpha-D-galactosamine(in) + UMP(out) = UDP-N-acetyl-alpha-D-galactosamine(out) + UMP(in)

Direction not assertedBalancedTransportRhea 72735

2 hydrogencarbonate(out) + chloride(in) + Na(+)(out) = 2 hydrogencarbonate(in) + chloride(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 72739

leukotriene C4(out) = leukotriene C4(in)

Direction not assertedBalancedTransportRhea 72743

leukotriene E4(out) = leukotriene E4(in)

Direction not assertedBalancedTransportRhea 72747

ochratoxin A + H2O = ochratoxin alpha + L-phenylalanine

Direction not assertedBalancedRhea 72751

3 ATP = 3',3',3'-c-tri-AMP + 3 diphosphate

Direction not assertedBalancedRhea 72755

anthocyanin A6 + malonyl-CoA = anthocyanin A8 + CoA

Direction not assertedBalancedRhea 72759

anthocyanin A10 + malonyl-CoA = anthocyanin A11 + CoA

Direction not assertedBalancedRhea 72763

4 malonyl-CoA + acetyl-CoA + 5 NADPH + 9 H(+) = 7-methylmellein + 3 CO2 + 5 NADP(+) + 5 CoA + 4 H2O

Direction not assertedBalancedRhea 72767

7-methylmellein + 3 reduced [NADPH--hemoprotein reductase] + 3 O2 = 7-carboxymellein + 3 oxidized [NADPH--hemoprotein reductase] + 4 H2O + 4 H(+)

Direction not assertedBalance undeterminableRhea 72771

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