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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

1,451–1,500 of 18,558 reactions from Rhea

chondroitin beta-D-glucuronate + n 3'-phosphoadenylyl sulfate = chondroitin 4'-sulfate + n adenosine 3',5'-bisphosphate + n H(+)
Direction not assertedBalance undeterminableRhea 16101
a (3S)-3-hydroxyacyl-CoA = a (2E)-enoyl-CoA + H2O
ReversibleBalance undeterminableRhea 16105
beta-D-fructose 6-phosphate + ATP = beta-D-fructose 1,6-bisphosphate + ADP + H(+)
Left to rightBalancedRhea 16109
2 cob(II)alamin-[cyanocobalamin reductase] + 2 hydrogen cyanide + NADP(+) = 2 cyanocob(III)alamin + 2 apo-[cyanocobalamin reductase] + NADPH + H(+)
Right to leftBalance undeterminableRhea 16113
acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate
Left to rightBalancedRhea 16117
5,6-dihydrouracil + H2O = 3-(carbamoylamino)propanoate + H(+)
Direction not assertedBalancedRhea 16121
D-fructose + ATP = D-fructose 6-phosphate + ADP + H(+)

Left to rightBalancedRhea 16125

pyridoxine + NADP(+) = pyridoxal + NADPH + H(+)

Direction not assertedBalancedRhea 16129

N(1)-acetylspermine + O2 + H2O = N(1)-acetylspermidine + 3-aminopropanal + H2O2

Direction not assertedBalancedRhea 16133

2'-deoxymugineate + NADP(+) = 3''-deamino-3''-oxonicotianamine + NADPH + H(+)

Direction not assertedBalancedRhea 16137

2'-deoxymugineate + NAD(+) = 3''-deamino-3''-oxonicotianamine + NADH + H(+)

Direction not assertedBalancedRhea 16141

CMP-N-acetyl-beta-neuraminate + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = CMP-N-glycoloyl-beta-neuraminate + 2 Fe(III)-[cytochrome b5] + H2O

Direction not assertedBalance undeterminableRhea 16145

beta-nicotinamide D-ribonucleotide + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + nicotinamide + H(+)

Right to leftBalancedRhea 16149

a primary methyl amine + O2 + H2O = an aldehyde + H2O2 + NH4(+)

Left to rightBalance undeterminableRhea 16153

2 Fe(III)-[leghemoglobin] + NADPH = 2 Fe(II)-[leghemoglobin] + NADP(+) + H(+)

Direction not assertedBalance undeterminableRhea 16157

2 Fe(III)-[leghemoglobin] + NADH = 2 Fe(II)-[leghemoglobin] + NAD(+) + H(+)

Direction not assertedBalance undeterminableRhea 16161

L-tryptophan + O2 = indole-3-acetamide + CO2 + H2O

Direction not assertedBalancedRhea 16165

L-glutamate + NH4(+) + ATP = L-glutamine + ADP + phosphate + H(+)

Direction not assertedBalancedRhea 16169

(4-hydroxyphenyl)acetaldehyde + dopamine = (S)-norcoclaurine + H2O

Direction not assertedBalancedRhea 16173

retinal + NAD(+) + H2O = retinoate + NADH + 2 H(+)

Left to rightBalancedRhea 16177

3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 16181

an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)

Left to rightBalance undeterminableRhea 16185

3-(4-hydroxyphenyl)pyruvate + O2 = homogentisate + CO2

Left to rightBalancedRhea 16189

an (R)-2-haloacid + H2O = a (2R)-2-hydroxycarboxylate + a halide anion + H(+)

Direction not assertedBalance undeterminableRhea 16193

(3S)-3-hydroxybutanoyl-CoA + NADP(+) = acetoacetyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 16197

4-amino-4-deoxychorismate = 4-aminobenzoate + pyruvate + H(+)

Direction not assertedBalancedRhea 16201

N(6)-(6-O-phospho-D-fructosyl)-L-lysyl-[protein] + H2O = N(6)-(D-fructosyl)-L-lysyl-[protein] + phosphate

Direction not assertedBalance undeterminableRhea 16205

Co-precorrin-8X = cob(II)yrinate

Direction not assertedBalancedRhea 16209

3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 16213

L-arabinono-1,4-lactone + H2O = L-arabinonate + H(+)

Direction not assertedBalancedRhea 16217

3-O-(beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(alpha-D-GlcNAc-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl)-L-seryl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 16221

1,8-diazacyclotetradecane-2,9-dione + H2O = N-(6-aminohexanoyl)-6-aminohexanoate

Direction not assertedBalancedRhea 16225

a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate

Left to rightBalance undeterminableRhea 16229

(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH + H(+)

Direction not assertedBalancedRhea 16233

[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)

Direction not assertedBalance undeterminableRhea 16237

an NDP-alpha-D-glucose + D-fructose = a ribonucleoside 5'-diphosphate + sucrose + H(+)

Direction not assertedBalance undeterminableRhea 16241

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA

Direction not assertedBalance undeterminableRhea 16245

alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate

ReversibleBalancedRhea 16249

(3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = phenanthrene-3,4-diol + NADH + H(+)

Direction not assertedBalancedRhea 16253

alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate

Direction not assertedBalancedRhea 16257

succinyl-CoA + L-lysyl-[protein] = N(6)-succinyl-L-lysyl-[protein] + CoA + H(+)

Left to rightBalance undeterminableRhea 16261

trans-5-O-(4-coumaroyl)-D-quinate + reduced [NADPH--hemoprotein reductase] + O2 = 5-O-[(E)-caffeoyl]-D-quinate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 16265

N,N-dimethyl-1,4-phenylenediamine + aniline + 2 NADP(+) = 4-(dimethylamino)azobenzene + 2 NADPH + 2 H(+)

Direction not assertedBalancedRhea 16269

CDP-choline + an N-acylsphing-4-enine = a sphingomyelin + CMP + H(+)

Direction not assertedBalance undeterminableRhea 16273

indole-3-acetaldehyde + O2 + H2O = (indol-3-yl)acetate + H2O2 + H(+)

Direction not assertedBalancedRhea 16277

dihydrostreptomycin 6-phosphate + ATP = dihydrostreptomycin 3'alpha,6-bisphosphate + ADP + H(+)

Direction not assertedBalancedRhea 16281

D-octopine + NAD(+) + H2O = L-arginine + pyruvate + NADH + H(+)

Direction not assertedBalancedRhea 16285

(1R,2S)-ephedrine + NAD(+) = (R)-2-methylimino-1-phenylpropan-1-ol + NADH + 2 H(+)

Direction not assertedBalancedRhea 16289

2-isopropylmaleate + H2O = (2S)-2-isopropylmalate

Direction not assertedBalancedRhea 16293

5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + NADPH + H(+)

Right to leftBalancedRhea 16297

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