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Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
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Reference

Evidence

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Outcomes
Proteins
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Reactions
Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

101–150 of 18,558 reactions from Rhea

4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA
Right to leftBalancedRhea 10408
ADP-D-ribose + H2O = D-ribose 5-phosphate + AMP + 2 H(+)
Left to rightBalancedRhea 10412
toluene + fumarate = 2-benzylsuccinate
Direction not assertedBalancedRhea 10416
taurine + pyruvate = sulfoacetaldehyde + L-alanine
Direction not assertedBalancedRhea 10420
N-benzoylglycine + H2O = benzoate + glycine
Direction not assertedBalancedRhea 10424
(5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12S)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
Left to rightBalancedRhea 10428
2-(acetamidomethylene)succinate + 2 H2O + H(+) = succinate semialdehyde + acetate + NH4(+) + CO2

? Direction not asserted

Balanced

Rhea 10432

7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oyl-CoA = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oyl-CoA + H2O

Direction not assertedBalancedRhea 10436

D-glucono-1,5-lactone + H2O = D-gluconate + H(+)

Direction not assertedBalancedRhea 10440

(S)-reticuline + S-adenosyl-L-methionine = (S)-laudanine + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 10444

a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O

Direction not assertedBalance undeterminableRhea 10448

2-(L-cystein-S-yl)-2-(1H-indol-3-yl)-acetonitrile + reduced [NADPH--hemoprotein reductase] + O2 = (R)-dihydrocamalexate + hydrogen cyanide + oxidized [NADPH--hemoprotein reductase] + 2 H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 10452

D-maltose + acetyl-CoA = 1-O-acetylmaltose + CoA

Direction not assertedBalancedRhea 10456

prostaglandin A1 = prostaglandin C1

Direction not assertedBalancedRhea 10460

[(1->4)-N-acetyl-beta-D-glucosaminyl](n) + n H2O = chitosan + n acetate

Direction not assertedBalance undeterminableRhea 10464

D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O

Direction not assertedBalancedRhea 10468

(2R,3S)-2,3-dimethylmalate = propanoate + pyruvate

Direction not assertedBalancedRhea 10472

4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate

Direction not assertedBalancedRhea 10480

N-feruloylglycine + H2O = (E)-ferulate + glycine

Direction not assertedBalancedRhea 10484

(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = (6R)-5,10-methenyltetrahydrofolate + ADP + phosphate

Direction not assertedBalancedRhea 10488

phosphocholine + H2O = choline + phosphate

Direction not assertedBalancedRhea 10492

butanoyl-CoA + glyoxylate + H2O = 3-ethylmalate + CoA + H(+)

Direction not assertedBalancedRhea 10500

D-sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate

Right to leftBalancedRhea 10508

(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + NADH + H(+)

Direction not assertedBalancedRhea 10516

a 1,2-diacyl-3-O-(beta-D-galactosyl)-sn-glycerol + UDP-alpha-D-galactose = a 1,2-diacyl-3-O-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-sn-glycerol + UDP + H(+)

Direction not assertedBalance undeterminableRhea 10520

2-oxoglutarate + H(+) = succinate semialdehyde + CO2

Direction not assertedBalancedRhea 10524

dihydrosanguinarine + reduced [NADPH--hemoprotein reductase] + O2 = 10-hydroxydihydrosanguinarine + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 10528

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + L-tryptophan + H2O

Direction not assertedBalancedRhea 10532

4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H2O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + sulfate + H(+)

Direction not assertedBalancedRhea 10536

7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde

Direction not assertedBalancedRhea 10540

L-arginine + O2 = 4-guanidinobutanamide + CO2 + H2O

Direction not assertedBalancedRhea 10548

D-glucose + O2 = 2-dehydro-D-glucose + H2O2

Direction not assertedBalancedRhea 10552

D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + phosphate + H(+)

Direction not assertedBalancedRhea 10556

4-hydroxy-1-pyrroline-2-carboxylate + H2O + H(+) = 2,5-dioxopentanoate + NH4(+)

Direction not assertedBalancedRhea 10560

oxaloacetate 4-methyl ester + H2O = methanol + oxaloacetate + H(+)

Direction not assertedBalancedRhea 10564

luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucuronide + UDP + H(+)

Direction not assertedBalancedRhea 10568

vinylacetyl-CoA = (2E)-butenoyl-CoA

Direction not assertedBalancedRhea 10572

N-methylethanolamine phosphate + CTP + H(+) = CDP-N-methylethanolamine + diphosphate

Direction not assertedBalancedRhea 10576

(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + L-glutamate + ATP = (6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n+1) + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 10580

4-coumaroyl-CoA + 3 malonyl-CoA + NADPH + 4 H(+) = isoliquiritigenin + 3 CO2 + NADP(+) + 4 CoA + H2O

Direction not assertedBalancedRhea 10584

a long-chain fatty acyl-[mycocerosate synthase] + 4 (R)-methylmalonyl-CoA + 8 NADPH + 12 H(+) = tetramethylated-mycocerosoyl-[mycocerosate synthase] + 4 CO2 + 8 NADP(+) + 4 CoA + 4 H2O

Direction not assertedBalance undeterminableRhea 10588

a 3',5'-unsubstituted flavanone + reduced [NADPH--hemoprotein reductase] + O2 = a 3'-hydroxy,5'-unsubstituted flavanone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 10592

L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)

Left to rightBalance undeterminableRhea 10596

prostaglandin H2 = prostaglandin D2

Left to rightBalancedRhea 10600

a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = phosphocholine + a 1,2-diacyl-sn-glycerol + H(+)

Left to rightBalance undeterminableRhea 10604

(E)-cinnamate + reduced [NADPH--hemoprotein reductase] + O2 = (E)-4-coumarate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 10608

N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP-alpha-D-xylose = N(4)-{beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-[beta-D-Xyl-(1->2)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-asparaginyl-[protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 10612

(2R,3S)-catechin + NADP(+) + H2O = (2R,3S,4S)-leucocyanidin + NADPH + H(+)

Direction not assertedBalancedRhea 10616

(E)-cinnamaldehyde + NADP(+) + CoA = (E)-cinnamoyl-CoA + NADPH + H(+)

Direction not assertedBalancedRhea 10620

tRNA(n+1) + phosphate = tRNA(n) + a ribonucleoside 5'-diphosphate

Direction not assertedBalance undeterminableRhea 10628

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