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Subsystem: Xenobiotics metabolism Remove
101–150 of 158 reactions in Xenobiotics metabolism
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol[c] + UDP-glucuronate[c] = 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronide[c] + UDP[c]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR07065
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol[c] + UDP-glucuronate[c] = NNAL-N-glucuronide[c] + UDP[c]
Left to rightBalancedEC 2.4.1.17Human-GEM MAR07066
4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol[c] + H+[c] + NADPH[c] + O2[c] = 4-(methylnitrosamino)-1-(3-pyridyl-N-oxide)-1-butanol[c] + H2O[c] + NADP+[c]
Left to rightBalancedHuman-GEM MAR07067
4-[(hydroxymethyl)nitrosoamino]-1-(3-pyridinyl)-1-butanone[c] = 4-(nitrosoamino)-1-(3-pyridinyl)-1-butanone[c] + formaldehyde[c]
Left to rightBalancedHuman-GEM MAR07068
4-(nitrosoamino)-1-(3-pyridinyl)-1-butanone[c] = 4-hydroxy-1-(3-pyridinyl)-1-butanone[c] + nitrogen[c]
Left to rightBalancedHuman-GEM MAR07069
4-hydroxy-1-(3-pyridinyl)-1-butanone[c] + NADPH[c] + O2[c] = 3-succinoylpyridine[c] + H+[c] + H2O[c] + NADP+[c]
Left to rightUnbalancedHuman-GEM MAR07070
4-hydroxy-4-(methylnitrosoamino)-1-(3-pyridinyl)-1-butanone[c] = 4-oxo-1-(3-pyridyl)-1-butanone[c] + N-nitrosomethanamine[c]
Left to rightBalancedHuman-GEM MAR07071
4-oxo-1-(3-pyridyl)-1-butanone[c] + H+[c] + NADPH[c] + O2[c] = 3-succinoylpyridine[c] + H2O[c] + NADP+[c]
Left to rightBalancedHuman-GEM MAR07072
1-(methylnitrosoamino)-4-(3-pyridinyl)-1,4-butanediol[c] = 5-(3-pyridyl)-2-hydroxytetrahydrofuran[c] + N-nitrosomethanamine[c]
Left to rightBalancedHuman-GEM MAR07073
5-(3-pyridyl)-2-hydroxytetrahydrofuran[c] + NADPH[c] + O2[c] = gamma-hydroxy-3-pyridinebutanoate[c] + H2O[c] + NADP+[c]
Left to rightBalancedHuman-GEM MAR07074
alpha-[3-(nitrosoamino)propyl]-3-pyridinemethanol[c] = 1-(3-pyridinyl)-1,4-butanediol[c] + nitrogen[c]
Left to rightBalancedHuman-GEM MAR07075
1-(3-pyridinyl)-1,4-butanediol[c] + NADPH[c] + O2[c] = gamma-hydroxy-3-pyridinebutanoate[c] + 2 H+[c] + H2O[c] + NADP+[c]
Left to rightUnbalancedHuman-GEM MAR07076
alpha-[3-[(hydroxymethyl)nitrosoamino]propyl]-3-pyridinemethanol[c] = alpha-[3-(nitrosoamino)propyl]-3-pyridinemethanol[c] + formaldehyde[c]
Left to rightBalancedHuman-GEM MAR07077
1-nitronaphthalene[c] + 2 H+[c] + NADPH[c] + O2[c] = 1-nitronaphthalene-5,6-oxide[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07078
1-nitronaphthalene-5,6-oxide[c] + GSH[c] + H+[c] = 1-nitro-5-hydroxy-6-glutathionyl-5,6-dihydronaphthalene[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07079
1-nitronaphthalene-5,6-oxide[c] + GSH[c] + H+[c] = 1-nitro-5-glutathionyl-6-hydroxy-5,6-dihydronaphthalene[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07080
1-nitronaphthalene-5,6-oxide[c] + H2O[c] = 1-nitro-5,6-dihydroxy-dihydronaphthalene[c]
Left to rightBalancedEC 3.3.2.9Human-GEM MAR07081
1-nitronaphthalene[c] + 2 H+[c] + NADPH[c] + O2[c] = 1-nitronaphthalene-7,8-oxide[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07082
1-nitronaphthalene-7,8-oxide[c] + GSH[c] + H+[c] = 1-nitro-7-hydroxy-8-glutathionyl-7,8-dihydronaphthalene[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07083
1-nitronaphthalene-7,8-oxide[c] + GSH[c] + H+[c] = 1-nitro-7-glutathionyl-8-hydroxy-7,8-dihydronaphthalene[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07084
1-nitronaphthalene[c] + 3 H+[c] = 1-nitrosonaphthalene[c] + H2O[c]
Left to rightUnbalancedHuman-GEM MAR07085
1-nitrosonaphthalene[c] + 2 H+[c] = N-hydroxy-1-aminonaphthalene[c]
Left to rightUnbalancedHuman-GEM MAR07086
2 H+[c] + N-hydroxy-1-aminonaphthalene[c] = 1-naphthylamine[c] + H2O[c]
Left to rightUnbalancedHuman-GEM MAR07087
1,1-dichloroethylene[c] + H+[c] + NADPH[c] + O2[c] = 2,2-dichloroacetaldehyde[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07088
2,2-dichloroacetaldehyde[c] + GSH[c] + H+[c] = S-(2,2-dichloro-1-hydroxy)ethyl glutathione[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07089
2,2-dichloroacetaldehyde[c] + H2O[c] = 2,2-dichloro-1,1-ethanediol[c]
Left to rightBalancedHuman-GEM MAR07090
1,1-dichloroethylene[c] + H+[c] + NADPH[c] + O2[c] = 1,1-dichloroethylene epoxide[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07091
1,1-dichloroethylene epoxide[c] + GSH[c] = 2-(S-glutathionyl)acetyl chloride[c] + hydrochloride[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07092
2-(S-glutathionyl)acetyl chloride[c] + GSH[c] = 2-(S-glutathionyl)acetyl glutathione[c] + hydrochloride[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07093
2-(S-glutathionyl)acetyl chloride[c] + H2O[c] = 2-S-glutathionyl acetate[c] + chloride[c] + H+[c]
Left to rightBalancedHuman-GEM MAR07094
2-(S-glutathionyl)acetyl glutathione[c] + H2O[c] = 2-S-glutathionyl acetate[c] + GSH[c]
Left to rightBalancedHuman-GEM MAR07095
1,1-dichloroethylene[c] + H+[c] + NADPH[c] + O2[c] = chloroacetyl chloride[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07096
chloroacetyl chloride[c] + GSH[c] = hydrochloride[c] + S-(2-chloroacetyl)glutathione[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07097
chloroacetyl chloride[c] + H2O[c] = chloride[c] + chloroacetic acid[c] + 2 H+[c]
Left to rightBalancedHuman-GEM MAR07098
1,2-dibromoethane[c] + NADPH[c] + O2[c] = 2-bromoacetaldehyde[c] + H2O[c] + hydrobromic acid[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR07099
2-bromoacetaldehyde[c] + GSH[c] = 2 H+[c] + hydrobromic acid[c] + S-(formylmethyl)glutathione[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07100
1,2-dibromoethane[c] + GSH[c] = glutathione episulfonium ion[c] + 2 H+[c] + 2 hydrobromic acid[c]
Left to rightBalancedEC 2.5.1.18Human-GEM MAR07103
glutathione episulfonium ion[c] + H2O[c] = S-(2-hydroxyethyl)glutathione[c]
Left to rightBalancedHuman-GEM MAR07104
3 H+[c] + S-(formylmethyl)glutathione[c] = S-(2-hydroxyethyl)glutathione[c]
Left to rightUnbalancedHuman-GEM MAR07106
PAPS[c] + PNP[c] = 4-nitrophenyl-sulfate[c] + H+[c] + PAP[c]
Left to rightBalancedEC 2.8.2.1Human-GEM MAR07688
debrisoquin[c] + H+[c] + NADPH[c] + O2[c] = 4-hydroxy-debrisoquine[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR08032
H+[c] + NADPH[c] + O2[c] + PNP[c] = 4-nitrocatechol[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR08034
H+[c] + lauric acid[c] + NADPH[c] + O2[c] = 12-hydroxydodecanoic acid[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.15.3Human-GEM MAR08036
H+[c] + myristic acid[c] + NADPH[c] + O2[c] = 14-hydroxytetradecanoic acid[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.15.3Human-GEM MAR08037
H+[c] + NADPH[c] + O2[c] + palmitate[c] = 16-hydroxyhexadecanoic acid[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.15.3Human-GEM MAR08038
coumarin[c] + H+[c] + NADPH[c] + O2[c] = H2O[c] + NADP+[c] + umbelliferone[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR08040
antipyrine[c] + H+[c] + NADPH[c] + 0.5 O2[c] = edaravone[c] + methanol[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR08043
H+[c] + NADPH[c] + O2[c] + omeprazole[c] = 5-hydroxy-omeprazole[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR08046
H+[c] + NADPH[c] + O2[c] + paclitaxel[c] = 6-hydroxypaclitaxel[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR08049
H+[c] + NADPH[c] + O2[c] + tolbutamide[c] = 4-hydroxy-tolbutamide[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.13.-Human-GEM MAR08052