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Subsystem: Arachidonic acid metabolism Remove
101–138 of 138 reactions in Arachidonic acid metabolism
8(S)-HPETE[c] + 2 GSH[c] = 8(S)-HETE[c] + GSSG[c] + H2O[c]
Left to rightBalancedEC 1.13.11.31Human-GEM MAR01063
arachidonate[c] + O2[c] = (11R)-HPETE[c]
Left to rightBalancedEC 1.13.11.31Human-GEM MAR01064
11,12-EET[c] + ATP[c] + CoA[c] + 2 H2O[c] + NAD+[c] + O2[c] = 9,10-epoxy-(6Z,12Z)-octadecadienoic acid[c] + acetyl-CoA[c] + AMP[c] + H2O2[c] + NADH[c] + PPi[c]
Left to rightUnbalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Human-GEM MAR01065
9,10-epoxy-(6Z,12Z)-octadecadienoic acid[c] + ATP[c] + CoA[c] + 2 H2O[c] + NAD+[c] + O2[c] = 7,8-epoxy-(4Z,10Z)-hexadecadienoic acid[c] + acetyl-CoA[c] + AMP[c] + 2 H+[c] + H2O2[c] + NADH[c] + PPi[c]
Left to rightBalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Human-GEM MAR01066
7,8-epoxy-(4Z,10Z)-hexadecadienoic acid[c] + ATP[c] + CoA[c] + 2 H2O[c] + NAD+[c] + O2[c] = 5,6-epoxy-(8Z)-tetradecenoic acid[c] + acetyl-CoA[c] + AMP[c] + H2O2[c] + NADH[c] + PPi[c]
Left to rightUnbalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Human-GEM MAR01067
14,15-EET[c] + ATP[c] + CoA[c] + 2 H2O[c] + NAD+[c] + O2[c] = 12,13-epoxy-(6Z,9Z)-octadecadienoic acid[c] + acetyl-CoA[c] + AMP[c] + H2O2[c] + NADH[c] + PPi[c]
Left to rightUnbalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Human-GEM MAR01068
12,13-epoxy-(6Z,9Z)-octadecadienoic acid[c] + ATP[c] + CoA[c] + 2 H2O[c] + NAD+[c] + O2[c] = 10,11-epoxy-(4Z,7Z)-hexadecadienoic acid[c] + acetyl-CoA[c] + AMP[c] + 2 H+[c] + H2O2[c] + NADH[c] + PPi[c]
Left to rightBalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Human-GEM MAR01069
10,11-epoxy-(4Z,7Z)-hexadecadienoic acid[c] + ATP[c] + CoA[c] + H+[c] + 2 H2O[c] + NAD+[c] + O2[c] = 8,9-epoxy-(5Z)-tetradecenoic acid[c] + acetyl-CoA[c] + AMP[c] + H2O2[c] + NADH[c] + PPi[c]
Left to rightUnbalancedEC 1.1.1.35, 1.3.3.6, 2.3.1.176, 2.3.1.16, 3.1.2.2, 4.2.1.17, 5.1.99.4, 6.2.1.-Human-GEM MAR01070
12(S)-HETE[c] + H+[c] + NADPH[c] + O2[c] = 12,20-diHETE[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.94Human-GEM MAR01071
12(S)-HETE[r] + H+[r] + NADPH[r] + O2[r] = 12,20-diHETE[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.94Human-GEM MAR01072
12(S)-HETE[c] + 2 H+[c] + O2[c] = 11,12-dihydroxy-(5E,7E,9E,14Z)-eicosatetraenoate[c] + H2O[c]
Left to rightUnbalancedEC 1.13.11.31Human-GEM MAR01073
12(S)-HETE[c] + H+[c] + NADH[c] = 12-hetre[c] + NAD+[c]
ReversibleBalancedEC 1.3.1.-Human-GEM MAR01074
12(S)-HETE[c] + 2 H+[c] + O2[c] = H2O[c] + leukotriene B4[c]
Left to rightUnbalancedEC 1.13.11.34Human-GEM MAR01075
12(S)-HETE[r] + 2 H+[r] + O2[r] = H2O[r] + leukotriene B4[r]
Left to rightUnbalancedEC 1.13.11.34Human-GEM MAR01077
arachidonate[c] + glycerol[c] + 5 H+[c] = 2 H2O[c] + noladin-ether[c]
Left to rightUnbalancedEC 3.5.1.99Human-GEM MAR01079
15(R)-HETE[n] + O2[n] = (5S,6S)-epoxy-(15R)-hydroxy-ETE[n] + H2O[n]
Left to rightBalancedEC 1.13.11.34Human-GEM MAR03005
arachidonyl-CoA[x] + H2O[x] = arachidonate[x] + CoA[x] + H+[x]
Left to rightBalancedEC 3.1.2.2, 3.1.2.22Human-GEM MAR03015
arachidonate[r] + FADH2[r] + O2[r] = 11,12-EET[r] + FAD[r] + H2O[r]
Left to rightBalancedEC 1.14.14.1Human-GEM MAR03788
leukotriene B4[c] + NADP+[c] = 5-oxo-12-HETE[c] + H+[c] + NADPH[c]
ReversibleBalancedEC 1.1.1.184Human-GEM MAR03886
leukotriene B4[m] + NADP+[m] = 5-oxo-12-HETE[m] + H+[m] + NADPH[m]
ReversibleBalancedEC 1.1.1.184Human-GEM MAR03887
leukotriene B4[x] + NADP+[x] = 5-oxo-12-HETE[x] + H+[x] + NADPH[x]
ReversibleBalancedEC 1.1.1.184Human-GEM MAR03888
5(S)-HETE[r] + H+[r] + NADPH[r] + O2[r] = 20-hydroxy-5S-HETE[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.94Human-GEM MAR03891
2 5(S)-HETE[n] + O2[n] = 2 5,15-DiHETE[n]
Left to rightBalancedEC 1.13.11.34Human-GEM MAR03893
5(S)-HETE[m] + NADP+[m] = 5-oxo-ETE[m] + H+[m] + NADPH[m]
ReversibleBalancedEC 1.1.1.184Human-GEM MAR03894
5(S)-HETE[x] + NADP+[x] = 5-oxo-ETE[x] + H+[x] + NADPH[x]
ReversibleBalancedEC 1.1.1.184Human-GEM MAR03896
2 12(S)-HETE[n] + O2[n] = 2 leukotriene B4[n]
Left to rightBalancedEC 1.13.11.34Human-GEM MAR03906
H+[c] + leukotriene B4[c] + NADPH[c] + O2[c] = 5,12,20-TriHETE[c] + H2O[c] + NADP+[c]
Left to rightBalancedEC 1.14.14.94Human-GEM MAR03909
H+[r] + leukotriene B4[r] + NADPH[r] + O2[r] = 5,12,20-TriHETE[r] + H2O[r] + NADP+[r]
Left to rightBalancedEC 1.14.14.94Human-GEM MAR03913
12(S)-HPETE[m] = hepoxilin A3[m]
ReversibleBalancedEC 1.11.1.9Human-GEM MAR03918
12(S)-HPETE[n] = hepoxilin A3[n]
ReversibleBalancedEC 1.11.1.9Human-GEM MAR03924
GSH[m] + hepoxilin A3[m] = hepoxilin A3-c[m]
ReversibleBalancedEC 2.5.1.18Human-GEM MAR03926
2 5(S)-HETE[n] + O2[n] = 2 leukotriene B4[n]
Left to rightBalancedEC 1.13.11.31Human-GEM MAR03927
2 5(S)-HETE[x] + O2[x] = 2 leukotriene B4[x]
Left to rightBalancedEC 1.13.11.31Human-GEM MAR03930
2 5-oxo-ETE[c] + O2[c] = 2 5-oxo-12-HETE[c]
Left to rightBalancedEC 1.13.11.31Human-GEM MAR03932
2 5-oxo-ETE[m] + O2[m] = 2 5-oxo-12-HETE[m]
Left to rightBalancedEC 1.13.11.31Human-GEM MAR03934
2 5-oxo-ETE[x] + O2[x] = 2 5-oxo-12-HETE[x]
Left to rightBalancedEC 1.13.11.31Human-GEM MAR03936
Left to rightBalancedEC 1.3.1.48Human-GEM MAR20018
Left to rightBalancedEC 1.3.1.48Human-GEM MAR20019