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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

14,751–14,800 of 18,558 reactions from Rhea

testosterone 17-sulfate(out) + 2 Na(+)(out) = testosterone 17-sulfate(in) + 2 Na(+)(in)
Direction not assertedBalancedTransportRhea 71375
D-aspartate(out) + K(+)(in) + 3 Na(+)(out) + H(+)(out) = D-aspartate(in) + K(+)(out) + 3 Na(+)(in) + H(+)(in)
Direction not assertedBalancedTransportRhea 71379
L-asparagine(in) + Na(+)(in) = L-asparagine(out) + Na(+)(out)
Right to leftBalancedTransportRhea 71383
L-pipecolate(in) + Na(+)(in) = L-pipecolate(out) + Na(+)(out)
Direction not assertedBalancedTransportRhea 71387
16alpha-hydroxydehydroepiandrosterone 3-sulfate(out) + 2 Na(+)(out) = 16alpha-hydroxydehydroepiandrosterone 3-sulfate(in) + 2 Na(+)(in)
Direction not assertedBalancedTransportRhea 71391
(5Z,8Z,11Z,14Z)-eicosatetraenoate(out) = (5Z,8Z,11Z,14Z)-eicosatetraenoate(in)
Left to rightBalancedTransport

Rhea 71395

taxusin + reduced [NADPH--hemoprotein reductase] + O2 = 2alpha-hydroxytaxusin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 71399

2alpha-hydroxytaxusin + reduced [NADPH--hemoprotein reductase] + O2 = 2alpha,7beta-dihydroxytaxusin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 71403

7beta-hydroxytaxusin + reduced [NADPH--hemoprotein reductase] + O2 = 2alpha,7beta-dihydroxytaxusin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 71407

3,3',5-triiodo-L-thyronine(out) + L-tryptophan(in) = 3,3',5-triiodo-L-thyronine(in) + L-tryptophan(out)

Direction not assertedBalancedTransportRhea 71411

3,3',5-triiodo-L-thyronine(out) + L-phenylalanine(in) = 3,3',5-triiodo-L-thyronine(in) + L-phenylalanine(out)

Direction not assertedBalancedTransportRhea 71415

3,3',5-triiodo-L-thyronine(out) + L-tyrosine(in) = 3,3',5-triiodo-L-thyronine(in) + L-tyrosine(out)

Direction not assertedBalancedTransportRhea 71419

an aromatic L-alpha-amino acid(in) + 3,3',5-triiodo-L-thyronine(out) = an aromatic L-alpha-amino acid(out) + 3,3',5-triiodo-L-thyronine(in)

Direction not assertedBalance undeterminableTransportRhea 71423

3,3'-diiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) = 3,3'-diiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)

Direction not assertedBalance undeterminableTransportRhea 71427

3,3',5'-triiodo-L-thyronine(out) + an aromatic L-alpha-amino acid(in) = 3,3',5'-triiodo-L-thyronine(in) + an aromatic L-alpha-amino acid(out)

Direction not assertedBalance undeterminableTransportRhea 71431

L-thyroxine(out) + an aromatic L-alpha-amino acid(in) = L-thyroxine(in) + an aromatic L-alpha-amino acid(out)

Direction not assertedBalance undeterminableTransportRhea 71435

L-dopa(out) + L-phenylalanine(in) = L-dopa(in) + L-phenylalanine(out)

Direction not assertedBalancedTransportRhea 71439

3-O-methyl-L-dopa(out) + L-phenylalanine(in) = 3-O-methyl-L-dopa(in) + L-phenylalanine(out)

Direction not assertedBalancedTransportRhea 71443

D-alanine(in) + Na(+)(in) = D-alanine(out) + Na(+)(out)

Direction not assertedBalancedTransportRhea 71447

bradykinin + H2O = L-Phe-L-Arg + bradykinin(1-7)

Left to rightBalancedRhea 71451

goralatide + H2O = N-acetyl-L-seryl-L-aspartate + L-lysyl-L-proline

Left to rightBalancedRhea 71455

substance P + H2O = substance P(1-9) + L-Leu-L-Met-NH2

Left to rightBalancedRhea 71459

substance P + H2O = substance P(1-8) + Gly-L-Leu-L-Met-NH2

Left to rightBalancedRhea 71463

substance P + H2O = substance P(1-7) + L-Phe-Gly-L-Leu-L-Met-NH2

Left to rightBalancedRhea 71467

substance P + H2O = L-Phe-L-Phe-Gly-L-Leu-L-Met-NH2 + substance P(1-6)

Left to rightBalancedRhea 71471

neurotensin + H2O = neurotensin(1-11) + L-isoleucyl-L-leucine

Left to rightBalancedRhea 71475

neurotensin + H2O = neurotensin(1-10) + L-tyrosyl-L-isoleucyl-L-leucine

Left to rightBalancedRhea 71479

Met-enkephalin + H2O = L-phenylalanyl-L-methionine + L-tyrosylglycylglycine

Left to rightBalancedRhea 71483

Leu-enkephalin + H2O = L-tyrosylglycylglycine + L-phenylalanyl-L-leucine

Left to rightBalancedRhea 71487

a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol(in) = a 6-(alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol(out)

Direction not assertedBalance undeterminableTransportRhea 71491

6-(alpha-D-glucosaminyl)-(1-octadecanoyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho)-1D-myo-inositol(in) = 6-(alpha-D-glucosaminyl)-(1-octadecanoyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho)-1D-myo-inositol(out)

Direction not assertedBalancedTransportRhea 71495

6-(N-acetyl-alpha-D-glucosaminyl)-(1-octadecanoyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho)-1D-myo-inositol(in) = 6-(N-acetyl-alpha-D-glucosaminyl)-(1-octadecanoyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho)-1D-myo-inositol(out)

Direction not assertedBalancedTransportRhea 71499

a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol(in) = a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositol(out)

Direction not assertedBalance undeterminableTransportRhea 71503

(+)-alpha-tocopherol(out) = (+)-alpha-tocopherol(in)

Direction not assertedBalancedTransportRhea 71507

phylloquinone(out) = phylloquinone(in)

Direction not assertedBalancedTransportRhea 71511

hypoxanthine(out) = hypoxanthine(in)

ReversibleBalancedTransportRhea 71515

uridine(out) = uridine(in)

ReversibleBalancedTransportRhea 71519

adenine(out) = adenine(in)

ReversibleBalancedTransportRhea 71523

thymine(out) = thymine(in)

ReversibleBalancedTransportRhea 71527

guanine(out) = guanine(in)

ReversibleBalancedTransportRhea 71531

D-glucose 6-phosphate(in) + phosphate(out) = D-glucose 6-phosphate(out) + phosphate(in)

Direction not assertedBalancedTransportRhea 71535

2 nitrate(out) + H(+)(out) = 2 nitrate(in) + H(+)(in)

Left to rightBalancedTransportRhea 71539

5-hydroxymethyl-dUMP in DNA + ATP = 5-phosphomethyl-dUMP in DNA + ADP + H(+)

Direction not assertedBalancedRhea 71543

5-phosphomethyl-dUMP in DNA + glycine = 5-N(alpha)-glycyl-dTMP in DNA + phosphate

Direction not assertedBalancedRhea 71547

5-N(alpha)-glycyl-dTMP in DNA + AH2 + S-adenosyl-L-methionine = 5-C(alpha)-glycyl-dTMP in DNA + 5'-deoxyadenosine + L-methionine + A + H(+)

Direction not assertedBalancedRhea 71551

5-C(alpha)-glycyl-dTMP in DNA + H(+) = 5-aminoethyl-dUMP in DNA + CO2

Direction not assertedBalancedRhea 71555

5-N(alpha)-glycyl-dTMP in DNA + A + H2O = 5-aminomethyl-dUMP in DNA + glyoxylate + AH2

Direction not assertedBalancedRhea 71559

5-aminomethyl-dUMP in DNA + acetyl-CoA = 5-acetylaminomethyl-dUMP in DNA + CoA + H(+)

Direction not assertedBalancedRhea 71563

5-phosphomethyl-dUMP in DNA + L-serine = 5-O-(L-seryl)-dTMP in DNA + phosphate

Direction not assertedBalancedRhea 71567

5-O-(L-seryl)-dTMP in DNA + H(+) = 5-aminoethoxy-methyl-dUMP in DNA + CO2

Direction not assertedBalancedRhea 71571

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