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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

14,601–14,650 of 18,558 reactions from Rhea

1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+)
Left to rightBalancedRhea 70771
6-sulfo-D-quinovose + FMNH2 + O2 = 6-dehydro-D-glucose + FMN + sulfite + H2O + 2 H(+)
Direction not assertedBalancedRhea 70775
D-glucose + NADP(+) = 6-dehydro-D-glucose + NADPH + H(+)
Direction not assertedBalancedRhea 70779
L-aspartate(in) + L-glutamate(out) + H(+)(out) = L-aspartate(out) + L-glutamate(in) + H(+)(in)
Direction not assertedBalancedTransportRhea 70783
L-citrulline(in) + L-ornithine(out) + H(+)(in) = L-citrulline(out) + L-ornithine(in) + H(+)(out)
Direction not assertedBalancedTransportRhea 70787
L-ornithine(out) + H(+)(in) = L-ornithine(in) + H(+)(out)
Direction not asserted

Balanced

Transport

Rhea 70791

L-lysine(out) + H(+)(in) = L-lysine(in) + H(+)(out)

Direction not assertedBalancedTransportRhea 70795

L-ornithine(out) + L-lysine(in) = L-ornithine(in) + L-lysine(out)

Direction not assertedBalancedTransportRhea 70799

6-deoxy-6-sulfo-D-fructose + D-glyceraldehyde 3-phosphate = 4-deoxy-4-sulfo-D-erythrose + D-xylulose 5-phosphate

Direction not assertedBalancedRhea 70803

4-deoxy-4-sulfo-D-erythrose = 4-deoxy-4-sulfo-D-erythrulose

Direction not assertedBalancedRhea 70807

4-deoxy-4-sulfo-D-erythrulose + D-glyceraldehyde 3-phosphate = sulfoacetaldehyde + D-xylulose 5-phosphate

Direction not assertedBalancedRhea 70811

L-histidine(in) + L-ornithine(out) + H(+)(in) = L-histidine(out) + L-ornithine(in) + H(+)(out)

Direction not assertedBalancedTransportRhea 70815

L-homoarginine(in) + L-ornithine(out) = L-homoarginine(out) + L-ornithine(in)

Direction not assertedBalancedTransportRhea 70819

L-lysine(out) + L-arginine(in) = L-lysine(in) + L-arginine(out)

Left to rightBalancedTransportRhea 70827

L-leucine(out) + L-arginine(in) + Na(+)(out) = L-leucine(in) + L-arginine(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70831

L-arginine(in) + L-glutamine(out) + Na(+)(out) = L-arginine(out) + L-glutamine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70835

L-histidine(out) + L-arginine(in) + Na(+)(out) = L-histidine(in) + L-arginine(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70839

L-arginine(in) + L-methionine(out) + Na(+)(out) = L-arginine(out) + L-methionine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70843

L-cysteine(out) + L-arginine(in) + Na(+)(out) = L-cysteine(in) + L-arginine(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70847

K(+)(in) + L-aspartate(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-aspartate(in) + 3 Na(+)(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 70851

L-serine(in) + L-glutamine(out) + Na(+)(out) = L-serine(out) + L-glutamine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70855

L-asparagine(in) + L-glutamine(out) + Na(+)(out) = L-asparagine(out) + L-glutamine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70859

L-threonine(in) + L-glutamine(out) + Na(+)(out) = L-threonine(out) + L-glutamine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70863

L-glutamine(in) + L-alanine(out) + Na(+)(out) = L-glutamine(out) + L-alanine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70867

L-valine(out) + L-glutamine(in) + Na(+)(out) = L-valine(in) + L-glutamine(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70871

L-glutamine(in) + L-methionine(out) + Na(+)(out) = L-glutamine(out) + L-methionine(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70875

L-threonine(out) + L-glutamine(in) + Na(+)(out) = L-threonine(in) + L-glutamine(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70879

L-glutamine(in) + L-glutamate(out) + Na(+)(out) + H(+)(out) = L-glutamine(out) + L-glutamate(in) + Na(+)(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 70883

L-serine(out) + L-glutamine(in) + Na(+)(out) = L-serine(in) + L-glutamine(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70887

L-asparagine(out) + L-glutamine(in) + Na(+)(out) = L-asparagine(in) + L-glutamine(out) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70891

N-terminal L-cysteinyl-[protein] + O2 = N-terminal S-hydroxy-S-oxy-L-cysteinyl-[protein] + H(+)

Left to rightBalance undeterminableRhea 70895

(2R)-3-phospho-glyceroyl phosphate + alpha-D-ribose 1-phosphate = alpha-D-ribose 1,5-bisphosphate + (2R)-3-phosphoglycerate + H(+)

Left to rightBalancedRhea 70899

2-deoxy-alpha-D-ribose 1-phosphate + (2R)-3-phospho-glyceroyl phosphate = 2-deoxy-alpha-D-ribose 1,5-bisphosphate + (2R)-3-phosphoglycerate + H(+)

Left to rightBalancedRhea 70903

(2R)-3-phospho-glyceroyl phosphate + alpha-D-mannose 1-phosphate = alpha-D-mannose 1,6-bisphosphate + (2R)-3-phosphoglycerate + H(+)

Left to rightBalancedRhea 70907

alpha-D-glucose 6-phosphate + (2R)-3-phospho-glyceroyl phosphate = alpha-D-glucose 1,6-bisphosphate + (2R)-3-phosphoglycerate + H(+)

Left to rightBalancedRhea 70911

guanosine(in) + H(+)(in) = guanosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70915

dopamine(out) + chloride(out) + Na(+)(out) = dopamine(in) + chloride(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70919

(R)-noradrenaline(out) + chloride(out) + Na(+)(out) = (R)-noradrenaline(in) + chloride(in) + Na(+)(in)

Direction not assertedBalancedTransportRhea 70923

(R)-glycerate(in) + H(+)(in) = (R)-glycerate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70927

dopamine(out) + chloride(out) + 2 Na(+)(out) = dopamine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 70931

L-lysine(in) = L-lysine(out)

Direction not assertedBalancedTransportRhea 70935

L-methionine(in) = L-methionine(out)

Direction not assertedBalancedTransportRhea 70939

L-isoleucine(in) = L-isoleucine(out)

Direction not assertedBalancedTransportRhea 70943

L-tryptophan(in) = L-tryptophan(out)

ReversibleBalancedTransportRhea 70947

D-serine + O2 + H2O = 3-hydroxypyruvate + H2O2 + NH4(+)

Left to rightBalancedRhea 70951

L-glutamate(in) + H(+)(in) = L-glutamate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70955

D-tyrosine + O2 + H2O = 3-(4-hydroxyphenyl)pyruvate + H2O2 + NH4(+)

Direction not assertedBalancedRhea 70959

D-phenylalanine + O2 + H2O = 3-phenylpyruvate + H2O2 + NH4(+)

Left to rightBalancedRhea 70963

3-sulfino-L-alanine(out) + L-glutamate(in) + H(+)(in) = 3-sulfino-L-alanine(in) + L-glutamate(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70967

D-dopa + O2 + H2O = 3-(3,4-dihydroxyphenyl)pyruvate + H2O2 + NH4(+)

Left to rightBalancedRhea 70971

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