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CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
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Reference

Evidence

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Reach

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Organisms
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Diseases

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

14,551–14,600 of 18,558 reactions from Rhea

D-glucose(out) + Na(+)(out) = D-glucose(in) + Na(+)(in)
Left to rightBalancedTransportRhea 70571
3',5'-cyclic UMP + H2O = UMP + H(+)
Left to rightBalancedRhea 70575
2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Left to rightBalancedRhea 70579
a 2-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-octadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
Left to rightBalance undeterminableRhea 70583
N-acetyl-alpha-D-glucosaminyl-[heparan sulfate](n) + H2O = alpha-D-glucosaminyl-[heparan sulfate](n) + acetate
Left to rightBalance undeterminableRhea 70587
2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Left to rightBalancedRhea 70591

a 2-acyl-sn-glycero-3-phosphoethanolamine + hexadecanoyl-CoA = 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphoethanolamine + CoA

Left to rightBalance undeterminableRhea 70595

a 2-acyl-sn-glycero-3-phosphoethanolamine + a fatty acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA

Left to rightBalance undeterminableRhea 70599

4-vinylphenol + NADH + H(+) = 4-ethylphenol + NAD(+)

Direction not assertedBalancedRhea 70603

4-ethylphenol + 3'-phosphoadenylyl sulfate = 4-ethylphenyl sulfate + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 70607

tetradecanoyl-[ACP] + L-lysyl-[protein] = N(6)-tetradecanoyl-L-lysyl-[protein] + holo-[ACP] + H(+)

Direction not assertedBalance undeterminableRhea 70611

hexadecanoyl-[ACP] + L-lysyl-[protein] = N(6)-hexadecanoyl-L-lysyl-[protein] + holo-[ACP] + H(+)

Direction not assertedBalance undeterminableRhea 70615

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70619

1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70623

N(6)-dodecanoyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-dodecanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]

Direction not assertedBalance undeterminableRhea 70627

N(6)-decanoyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-decanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]

Left to rightBalance undeterminableRhea 70631

N(6)-octanoyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-octanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]

Direction not assertedBalance undeterminableRhea 70635

N(6)-hexanoyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-hexanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]

Direction not assertedBalance undeterminableRhea 70639

D-proline(out) + H(+)(out) = D-proline(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 70643

D-serine(out) + H(+)(out) = D-serine(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 70647

(9Z)-hexadecenoyl-[ACP] + L-lysyl-[protein] = N(6)-[(9Z)-hexadecenoyl]-L-lysyl-[protein] + holo-[ACP] + H(+)

Direction not assertedBalance undeterminableRhea 70651

sarcosine(in) + H(+)(in) = sarcosine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70655

N,N-dimethylglycine(in) + H(+)(in) = N,N-dimethylglycine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70659

4-hydroxy-L-proline(in) + H(+)(in) = 4-hydroxy-L-proline(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70663

a fatty acyl-[ACP] + L-lysyl-[protein] = N(6)-(fatty acyl)-L-lysyl-[protein] + holo-[ACP] + H(+)

Direction not assertedBalance undeterminableRhea 70667

N-terminal glycyl-L-lysyl-[protein] + tetradecanoyl-CoA = N-terminal glycyl-(N(6)-tetradecanoyl)-L-lysyl-[protein] + CoA + H(+)

Left to rightBalance undeterminableRhea 70671

Met-enkephalin-Arg-Phe + H2O = L-arginyl-L-phenylalanine + Met-enkephalin

Left to rightBalancedRhea 70675

glycine betaine(in) + H(+)(in) = glycine betaine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70679

(R)-normetanephrine + S-adenosyl-L-methionine = (R)-metanephrine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70683

4-aminobutanoate(out) + chloride(out) + 2 Na(+)(out) = 4-aminobutanoate(in) + chloride(in) + 2 Na(+)(in)

ReversibleBalancedTransportRhea 70687

glycine(out) + chloride(out) + 2 Na(+)(out) = glycine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 70691

glycine(out) + chloride(out) + 3 Na(+)(out) = glycine(in) + chloride(in) + 3 Na(+)(in)

Direction not assertedBalancedTransportRhea 70695

K(+)(in) + L-glutamate(out) + 3 Na(+)(out) + H(+)(out) = K(+)(out) + L-glutamate(in) + 3 Na(+)(in) + H(+)(in)

Direction not assertedBalancedTransportRhea 70699

D-cycloserine(in) + H(+)(in) = D-cycloserine(out) + H(+)(out)

Direction not assertedBalancedTransportRhea 70703

6-sulfo-beta-D-quinovose = 6-sulfo-D-rhamnose

Direction not assertedBalancedRhea 70707

D-alanine(in) = D-alanine(out)

Direction not assertedBalancedTransportRhea 70711

glycine(in) = glycine(out)

Direction not assertedBalancedTransportRhea 70715

L-alanine(in) = L-alanine(out)

ReversibleBalancedTransportRhea 70719

sitosterol(out) = sitosterol(in)

Direction not assertedBalancedTransportRhea 70723

3-(6-sulfo-alpha-D-quinovosyl)glycerol + H2O = 6-sulfo-alpha-D-quinovose + glycerol

Direction not assertedBalancedRhea 70727

4-aminobutanoate(out) + chloride(out) + 3 Na(+)(out) = 4-aminobutanoate(in) + chloride(in) + 3 Na(+)(in)

Left to rightBalancedTransportRhea 70731

glycine betaine(out) + chloride(out) + 2 Na(+)(out) = glycine betaine(in) + chloride(in) + 2 Na(+)(in)

Direction not assertedBalancedTransportRhea 70735

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70739

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70743

1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70747

1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70751

1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70755

1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-methionine = 1,2-di-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70759

1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphoethanolamine + S-adenosyl-L-methionine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70763

1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N-methylethanolamine + S-adenosyl-L-methionine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phospho-N,N-dimethylethanolamine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70767

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