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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

14,501–14,550 of 18,558 reactions from Rhea

3-oxosphinganine + decanoyl-CoA = N-decanoyl-3-oxosphinganine + CoA + H(+)
Direction not assertedBalancedRhea 70371
3-oxosphinganine + dodecanoyl-CoA = N-dodecanoyl-3-oxosphinganine + CoA + H(+)
Direction not assertedBalancedRhea 70375
3-oxosphinganine + tetradecanoyl-CoA = N-tetradecanoyl-3-oxosphinganine + CoA + H(+)
Direction not assertedBalancedRhea 70379
3-oxosphinganine + hexadecanoyl-CoA = N-hexadecanoyl-3-oxosphinganine + CoA + H(+)
Direction not assertedBalancedRhea 70383
3-oxosphinganine + octadecanoyl-CoA = N-octadecanoyl-3-oxosphinganine + CoA + H(+)
Direction not assertedBalancedRhea 70387
3-oxosphinganine + eicosanoyl-CoA = N-eicosanoyl-3-oxosphinganine + CoA + H(+)
Direction not assertedBalancedRhea 70391
3-oxosphinganine + docosanoyl-CoA = N-docosanoyl-3-ketodihydrosphingosine + CoA + H(+)

Direction not assertedBalancedRhea 70395

3-oxosphinganine + tetracosanoyl-CoA = N-tetracosanoyl-3-oxosphinganine + CoA + H(+)

Direction not assertedBalancedRhea 70399

3-oxosphinganine + (9Z)-hexadecenoyl-CoA = N-(9Z-hexadecenoyl)-3-oxosphinganine + CoA + H(+)

Direction not assertedBalancedRhea 70403

[(2E,6E,10E)-geranylgeranyl]-L-cysteine + O2 + H2O = (2E,6E,10E)-geranylgeranial + L-cysteine + H2O2

Left to rightBalancedRhea 70407

4-hydroxyphenylacetyl-CoA + H2O = 4-hydroxyphenylacetate + CoA + H(+)

Direction not assertedBalancedRhea 70411

(3,5-dihydroxyphenyl)acetyl-CoA + H2O = (3,5-dihydroxyphenyl)acetate + CoA + H(+)

Direction not assertedBalancedRhea 70415

3,4-dihydroxyphenylacetyl-CoA + H2O = 3,4-dihydroxyphenylacetate + CoA + H(+)

Direction not assertedBalancedRhea 70419

an acyl-CoA + H2O = a carboxylate + CoA + H(+)

Direction not assertedBalance undeterminableRhea 70423

phenylacetyl-CoA + H2O = 2-phenylacetate + CoA + H(+)

Direction not assertedBalancedRhea 70427

Li(+)(in) + 2 H(+)(out) = Li(+)(out) + 2 H(+)(in)

Direction not assertedBalancedTransportRhea 70431

an N(3)-methyl-2'-deoxycytidine in single-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxycytidine in single-stranded DNA + formaldehyde + succinate + CO2 + H(+)

Left to rightBalance undeterminableRhea 70435

an N(3)-methyl-2'-deoxycytidine in double-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxycytidine in double-stranded DNA + formaldehyde + succinate + CO2 + H(+)

Left to rightBalance undeterminableRhea 70439

an N(1)-methyl-2'-deoxyadenosine in double-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxyadenosine in double-stranded DNA + formaldehyde + succinate + CO2 + H(+)

Left to rightBalance undeterminableRhea 70443

an N(1)-methyl-2'-deoxyadenosine in single-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxyadenosine in single-stranded DNA + formaldehyde + succinate + CO2 + H(+)

Left to rightBalance undeterminableRhea 70447

an N(1)-ethyl-2'-deoxyadenosine in single-stranded DNA + 2-oxoglutarate + O2 = a 2'-deoxyadenosine in single-stranded DNA + acetaldehyde + succinate + CO2 + H(+)

Direction not assertedBalance undeterminableRhea 70451

sarcosine + (6S)-5,6,7,8-tetrahydrofolate + O2 = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O2

Direction not assertedBalancedRhea 70455

a 1,N(6)-etheno-2'-deoxyadenosine in single-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxyadenosine in single-stranded DNA + glyoxal + succinate + CO2

Left to rightBalance undeterminableRhea 70459

a 1,N(6)-etheno-2'-deoxyadenosine in double-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxyadenosine in double-stranded DNA + glyoxal + succinate + CO2

Left to rightBalance undeterminableRhea 70463

a 3,N(4)-etheno-2'-deoxycytidine in double-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxycytidine in double-stranded DNA + glyoxal + succinate + CO2

Left to rightBalance undeterminableRhea 70467

a 3,N(4)-etheno-2'-deoxycytidine in single-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxycytidine in single-stranded DNA + glyoxal + succinate + CO2

Left to rightBalance undeterminableRhea 70471

sphing-4-enine + 2 S-adenosyl-L-methionine = N,N-dimethylsphing-4-enine + 2 S-adenosyl-L-homocysteine + 2 H(+)

Direction not assertedBalancedRhea 70475

N(6)-biotinyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-biotinyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]

Left to rightBalance undeterminableRhea 70479

a 1,N(2)-etheno-2'-deoxyguanosine in single-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxyguanosine in single-stranded DNA + glyoxal + succinate + CO2

Direction not assertedBalance undeterminableRhea 70483

a 1,N(2)-etheno-2'-deoxyguanosine in double-stranded DNA + 2-oxoglutarate + O2 + H2O = a 2'-deoxyguanosine in double-stranded DNA + glyoxal + succinate + CO2

Left to rightBalance undeterminableRhea 70487

L-threonyl-[protein] + GDP-beta-L-fucose = 3-O-(alpha-L-fucosyl)-L-threonyl-[protein] + GDP + H(+)

Left to rightBalance undeterminableRhea 70491

D-glucose(out) + 2 Na(+)(out) = D-glucose(in) + 2 Na(+)(in)

Left to rightBalancedTransportRhea 70495

D-galactose(out) + 2 Na(+)(out) = D-galactose(in) + 2 Na(+)(in)

Left to rightBalancedTransportRhea 70499

isopentenyl diphosphate + H2O = isopentenyl phosphate + phosphate + H(+)

Left to rightBalancedRhea 70503

dimethylallyl diphosphate + H2O = dimethylallyl phosphate + phosphate + H(+)

Left to rightBalancedRhea 70507

3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 70511

3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + UDP-alpha-D-galactose = 3-O-(beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-alpha-L-Fuc)-L-seryl-[EGF-like domain protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 70515

(R)-octopamine + S-adenosyl-L-methionine = (R)-synephrine + S-adenosyl-L-homocysteine + H(+)

Left to rightBalancedRhea 70519

UDP-alpha-D-glucuronate + H(+) = UDP-alpha-D-apiose + CO2

Direction not assertedBalancedRhea 70523

N-acyl-3-oxosphinganine + NADH + H(+) = an N-acylsphinganine + NAD(+)

Direction not assertedBalance undeterminableRhea 70527

3-O-(alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 70531

L-seryl-[EGF-like domain protein] + GDP-beta-L-fucose = 3-O-(alpha-L-fucosyl)-L-seryl-[EGF-like domain protein] + GDP + H(+)

Direction not assertedBalance undeterminableRhea 70535

L-threonyl-[EGF-like domain protein] + GDP-beta-L-fucose = 3-O-(alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + GDP + H(+)

Direction not assertedBalance undeterminableRhea 70539

3-O-(alpha-L-fucosyl)-L-seryl-[protein] + UDP-alpha-D-glucose = 3-O-(beta-D-glucosyl-(1->3)-alpha-L-fucosyl)-L-seryl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 70543

3-O-(alpha-L-fucosyl)-L-threonyl-[protein] + UDP-alpha-D-glucose = 3-O-(beta-D-glucosyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[protein] + UDP + H(+)

Left to rightBalance undeterminableRhea 70547

3-O-(N-acetyl-beta-D-glucosaminyl-(1->3)-alpha-L-fucosyl)-L-threonyl-[EGF-like domain protein] + UDP-alpha-D-galactose = 3-O-(beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-alpha-L-Fuc)-L-threonyl-[EGF-like domain protein] + UDP + H(+)

Direction not assertedBalance undeterminableRhea 70551

a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H2O = N-acetyl-D-galactosamine + L-seryl-[protein]

Direction not assertedBalance undeterminableRhea 70555

a 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H2O = N-acetyl-D-galactosamine + L-threonyl-[protein]

Direction not assertedBalance undeterminableRhea 70559

N(6)-hexadecanoyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-hexadecanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]

Left to rightBalance undeterminableRhea 70563

N(6)-tetradecanoyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-tetradecanoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]

Left to rightBalance undeterminableRhea 70567

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