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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

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PathwaysReactions grouped under one name
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AssessmentsRegulatory determinations, transcribed
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Reference

Evidence

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

14,201–14,250 of 18,558 reactions from Rhea

N-(4-aminobutyl)-3-aminopropanal + NAD(+) + H2O = N-(2-carboxyethyl)putrescine + NADH + 2 H(+)
Direction not assertedBalancedRhea 69164
spermine monoaldehyde + NAD(+) + H2O = N-(2-carboxyethyl)spermidine + NADH + 2 H(+)
Direction not assertedBalancedRhea 69168
N(6)-(2E)-butenoyl-L-lysyl-[protein] + H2O = (2E)-2-butenoate + L-lysyl-[protein]
Left to rightBalance undeterminableRhea 69172
N(6)-(2-hydroxyisobutanoyl)-L-lysyl-[protein] + H2O = 2-hydroxy-2-methylpropanoate + L-lysyl-[protein]
Left to rightBalance undeterminableRhea 69176
thiamine diphosphate + ADP = thiamine triphosphate + AMP
Direction not assertedBalancedRhea 69180
sn-glycerol 1-phosphate + (2E,6E,10E,14E)-geranylfarnesyl diphosphate = sn-3-(O-farnesylgeranyl)glycerol 1-phosphate + diphosphate
Direction not assertedBalancedRhea 69184

gamma-L-glutamyl-L-glutamyl-[protein] + L-glutamate + ATP = L-glutamyl-gamma-L-glutamyl-L-glutamyl-[protein] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69188

L-glutamyl-[tubulin] + L-glutamate + ATP = gamma-L-glutamyl-L-glutamyl-[tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69192

L-glutamyl-[beta-tubulin] + L-glutamate + ATP = gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69196

gamma-L-glutamyl-L-glutamyl-[tubulin] + L-glutamate + ATP = L-glutamyl-gamma-L-glutamyl-L-glutamyl-[tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69200

gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + L-glutamate + ATP = L-glutamyl-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69204

(L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[tubulin] + L-glutamate + ATP = (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69208

(L-glutamyl)(n)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + L-glutamate + ATP = (L-glutamyl)(n+1)-gamma-L-glutamyl-L-glutamyl-[beta-tubulin] + ADP + phosphate + H(+)

Direction not assertedBalance undeterminableRhea 69212

(omega-1)-methyl-(3R)-hydroxy-fatty acyl-CoA + NADP(+) = (omega-1)-methyl-3-oxo-fatty acyl-CoA + NADPH + H(+)

Direction not assertedBalance undeterminableRhea 69216

a (Z)-glucosinolate + H2O = a (Z)-N-(sulfonatooxy)alkanimidothioate + D-glucose + H(+)

Direction not assertedBalance undeterminableRhea 69220

a (Z)-alkenyl glucosinolate + H2O = a (Z)-N-(sulfonatooxy)alkenimidothioate + D-glucose + H(+)

Direction not assertedBalance undeterminableRhea 69224

a (Z)-N-(sulfonatooxy)alkenimidothioate = an epithionitrile + sulfate

Direction not assertedBalance undeterminableRhea 69228

(Z)-3-hydroxypropyl glucosinolate + H2O = (Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)

Direction not assertedBalancedRhea 69232

(Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate = 4-hydroxybutylnitrile + sulfur + sulfate

Direction not assertedBalancedRhea 69236

glucoraphanin + H2O = (Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)

Direction not assertedBalancedRhea 69240

(Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate = 5-methylsulfinylpentyl nitrile + sulfur + sulfate

Direction not assertedBalancedRhea 69244

sinigrin + H2O = (Z)-N-(sulfonatooxy)prop-2-enimidothioate + D-glucose + H(+)

Direction not assertedBalancedRhea 69248

(Z)-N-(sulfonatooxy)prop-2-enimidothioate = 2-(thiiran-2-yl)acetonitrile + sulfate

Direction not assertedBalancedRhea 69252

progoitrin + H2O = (Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)

Direction not assertedBalancedRhea 69256

(Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate = (3R)-3-hydroxy-3-(thiiran-2-yl)propanenitrile + sulfate

Direction not assertedBalancedRhea 69260

a (Z)-N-(sulfonatooxy)alkanimidothioate = an isothiocyanate + sulfate

Direction not assertedBalance undeterminableRhea 69264

a (Z)-N-(sulfonatooxy)alkenimidothioate = an alkenyl isothiocyanate + sulfate

Direction not assertedBalance undeterminableRhea 69268

(Z)-N-(sulfonatooxy)prop-2-enimidothioate = allyl isothiocyanate + sulfate

Direction not assertedBalancedRhea 69272

(Z)-N-(sulfonatooxy)prop-2-enimidothioate = but-3-enenitrile + sulfur + sulfate

Direction not assertedBalancedRhea 69276

(Z)-3-hydroxypropyl-N-(sulfonatooxy)methanimidothioate = 3-hydroxypropyl isothiocyanate + sulfate

Direction not assertedBalancedRhea 69280

a 17beta-hydroxy steroid + NADP(+) = a 17-oxo steroid + NADPH + H(+)

Right to leftBalance undeterminableRhea 69284

(Z)-4-methylsufinylbutyl-N-(sulfonatooxy)methanimidothioate = sulforaphane + sulfate

Direction not assertedBalancedRhea 69288

(Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate = goitrin + sulfate

Direction not assertedBalancedRhea 69292

(Z)-(2R)-2-hydroxy-3-butenyl-N-(sulfonatooxy)methanimidothioate = 3-hydroxypent-4-ene nitrile + sulfur + sulfate

Direction not assertedBalancedRhea 69296

(Z)-phenyl-N-(sulfonatooxy)methanimidothioate = benzyl isothiocyanate + sulfate

Direction not assertedBalancedRhea 69300

(Z)-glucotropeolin + H2O = (Z)-phenyl-N-(sulfonatooxy)methanimidothioate + D-glucose + H(+)

Direction not assertedBalancedRhea 69304

(Z)-phenyl-N-(sulfonatooxy)methanimidothioate = phenylacetonitrile + sulfur + sulfate

Direction not assertedBalancedRhea 69308

(Z)-phenyl-N-(sulfonatooxy)methanimidothioate = benzyl thiocyanate + sulfate

Direction not assertedBalancedRhea 69312

(Z)-N-(sulfonatooxy)prop-2-enimidothioate = allyl thiocyanate + sulfate

Direction not assertedBalancedRhea 69316

glucoerucin + H2O = (Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate + D-glucose

Direction not assertedBalancedRhea 69320

(Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate = 4-methylsulfanylbutyl isothionate + sulfate + H(+)

Direction not assertedBalancedRhea 69324

(Z)-4-methylsulfanylbutyl-N-(sulfonatooxy)methanimidothioate = 5-(methylsulfanyl)pentanenitrile + sulfur + sulfate + H(+)

Direction not assertedBalancedRhea 69328

N(6)-(2E)-butenoyl-L-lysyl-[protein] + NAD(+) + H2O = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + nicotinamide + L-lysyl-[protein]

Left to rightBalance undeterminableRhea 69332

(E)-alk-1-en-1-SO-peroxol = (Z)-alkanethial oxide

Direction not assertedBalance undeterminableRhea 69336

(E)-prop-1-en-1-SO-peroxol = (Z)-propanethial S-oxide

Direction not assertedBalancedRhea 69340

(E)-but-1-en-1-SO-peroxol = (Z)-butanethial oxide

Direction not assertedBalancedRhea 69344

S-1-propenyl-L-cysteine sulfoxide = (E)-prop-1-en-1-SO-peroxol + 2-aminoprop-2-enoate

Direction not assertedBalancedRhea 69348

2 (E)-prop-1-en-1-SO-peroxol = thiosulfinate + H2O

Direction not assertedBalancedRhea 69352

hypobromite + L-tyrosyl-[protein] + H(+) = 3-bromo-L-tyrosyl-[protein] + H2O

Left to rightBalance undeterminableRhea 69356

L-tyrosyl-[protein] + bromide + H2O2 + H(+) = 3-bromo-L-tyrosyl-[protein] + 2 H2O

Left to rightBalance undeterminableRhea 69360

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