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CompoundsSubstances with curated findings
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ProteinsTransporters and enzymes
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ReactionsRhea and Human-GEM, by subsystem
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PathwaysReactions grouped under one name
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MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

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Reference

Evidence

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

14,151–14,200 of 18,558 reactions from Rhea

2-hydroxyoctadecanoate + O2 = 2-oxooctadecanoate + H2O2
Direction not assertedBalancedRhea 68964
mandelate + O2 = phenylglyoxylate + H2O2
Direction not assertedBalancedRhea 68968
sn-glycerol 3-phosphate + A = dihydroxyacetone phosphate + AH2
Direction not assertedBalancedRhea 68972
glycoursodeoxycholate + NADP(+) = 7-oxoglycolithocholate + NADPH + H(+)
Right to leftBalancedRhea 68976
tauroursodeoxycholate + NADP(+) = 7-oxotaurolithocholate + NADPH + H(+)
Right to leftBalancedRhea 68980
a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine + ATP + H2O = a 5-methyl-2'-deoxycytidine in DNA + S-adenosyl-L-homocysteine + ADP + phosphate + 2 H(+)
Direction not assertedBalance undeterminableRhea 68984
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1,2-dihexadecanoyl-sn-glycero-3-phosphocholine

ReversibleBalancedRhea 68988

3-amino-4-hydroxybenzoate + NADPH + O2 + H(+) = 3-amino-2,4-dihydroxybenzoate + NADP(+) + H2O

Direction not assertedBalancedRhea 68992

gibberellin A9 + 2-oxoglutarate + O2 = gibberellin A4 + succinate + CO2

Direction not assertedBalancedRhea 68996

3-amino-2,4-dihydroxybenzoate + S-adenosyl-L-methionine = 3-amino-2-hydroxy-4-methoxybenzoate + S-adenosyl-L-homocysteine + H(+)

Direction not assertedBalancedRhea 69000

3-amino-2-hydroxy-4-methoxybenzoate + nitrite + ATP = cremeomycin + AMP + diphosphate + H2O

Direction not assertedBalancedRhea 69004

L-aspartate + 3 NADPH + 3 O2 + 2 H(+) = 2-nitrobutanedioate + 3 NADP(+) + 4 H2O

Direction not assertedBalancedRhea 69008

5beta-dihydrotestosterone + NADPH + H(+) = 5beta-androstane-3beta,17beta-diol + NADP(+)

Left to rightBalancedRhea 69012

3alpha-hydroxy-5beta-pregnan-20-one + NADP(+) = 5beta-pregnan-3,20-dione + NADPH + H(+)

Right to leftBalancedRhea 69016

L-aspartate + NADPH + O2 = N-hydroxy-L-aspartate + NADP(+) + H2O

Direction not assertedBalancedRhea 69020

N-hydroxy-L-aspartate + NADPH + O2 + H(+) = N,N-dihydroxy-L-aspartate + NADP(+) + H2O

Direction not assertedBalancedRhea 69024

5beta-dihydrotestosterone + NADPH + H(+) = 5beta-androstane-3alpha,17beta-diol + NADP(+)

Direction not assertedBalancedRhea 69028

N,N-dihydroxy-L-aspartate = (2S)-2-nitrosobutanedioate + H2O

Direction not assertedBalancedRhea 69032

5beta-androstane-3,17-dione + NADPH + H(+) = 3beta-hydroxy-5beta-androstane-17-one + NADP(+)

Left to rightBalancedRhea 69036

(2S)-2-nitrosobutanedioate + NADPH + O2 + H(+) = 2-nitrobutanedioate + NADP(+) + H2O

Direction not assertedBalancedRhea 69040

2-nitrobutanedioate = fumarate + nitrite + H(+)

Direction not assertedBalancedRhea 69044

hexano-6-lactone + H2O = 6-hydroxyhexanoate + H(+)

Direction not assertedBalancedRhea 69048

N(omega)-methyl-L-arginine + 2 NADH + 3 O2 + H(+) = N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + 2 NAD(+) + 3 H2O

Direction not assertedBalancedRhea 69052

N(omega)-methyl-L-arginine + NADH + O2 + H(+) = N(delta)-hydroxy-N(omega)-methyl-L-arginine + NAD(+) + H2O

Direction not assertedBalancedRhea 69056

N(delta)-hydroxy-N(omega)-methyl-L-arginine + NADH + O2 = N(delta),N(omega')-dihydroxy-N(omega)-methyl-L-arginine + NAD(+) + H2O

Direction not assertedBalancedRhea 69060

N(delta),N(omega')-dihydroxy-N(omega)-methyl-L-arginine + O2 = N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + H2O

Direction not assertedBalancedRhea 69064

2 N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-L-citrulline + AH2 = 2 N(delta)-hydroxy-N(omega)-methyl-L-citrulline + 2 nitric oxide + A

Direction not assertedBalancedRhea 69068

serotonin + O2 + H2O = (5-hydroxyindol-3-yl)acetaldehyde + H2O2 + NH4(+)

Direction not assertedBalancedRhea 69072

(R)-noradrenaline + O2 + H2O = (R)-3,4-dihydroxymandelaldehyde + H2O2 + NH4(+)

Direction not assertedBalancedRhea 69076

3,4-dihydroxyphenylacetaldehyde + NAD(+) + H2O = 3,4-dihydroxyphenylacetate + NADH + 2 H(+)

Direction not assertedBalancedRhea 69080

acrolein + NAD(+) + H2O = acrylate + NADH + 2 H(+)

Direction not assertedBalancedRhea 69084

butanal + NAD(+) + H2O = butanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 69088

pentanal + NAD(+) + H2O = pentanoate + NADH + 2 H(+)

Direction not assertedBalancedRhea 69092

4-methylsulfanyl-2-oxobutanoate + L-kynurenine = kynurenate + L-methionine + H2O

Left to rightBalancedRhea 69096

4-methylsulfanyl-2-oxobutanoate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-methionine

Direction not assertedBalancedRhea 69100

2-oxo-3-sulfanylpropanoate + L-kynurenine = kynurenate + L-cysteine + H2O

Left to rightBalancedRhea 69104

2-oxo-3-sulfanylpropanoate + L-kynurenine = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-cysteine

Direction not assertedBalancedRhea 69108

L-2-aminoadipate + glyoxylate = 2-oxoadipate + glycine

Left to rightBalancedRhea 69112

L-tyrosine + glyoxylate = 3-(4-hydroxyphenyl)pyruvate + glycine

Direction not assertedBalancedRhea 69116

glyoxylate + L-phenylalanine = 3-phenylpyruvate + glycine

Direction not assertedBalancedRhea 69120

L-tryptophan + glyoxylate = indole-3-pyruvate + glycine

Direction not assertedBalancedRhea 69124

L-leucine + glyoxylate = 4-methyl-2-oxopentanoate + glycine

Direction not assertedBalancedRhea 69128

cadaverine + O2 + H2O = 5-aminopentanal + H2O2 + NH4(+)

Left to rightBalancedRhea 69132

spermine + 2 O2 + 2 H2O = spermine dialdehyde + 2 H2O2 + 2 NH4(+)

Direction not assertedBalancedRhea 69136

N-(4-aminobutyl)-3-aminopropanal = acrolein + putrescine

Direction not assertedBalancedRhea 69140

agmatine + O2 + H2O = 4-guanidinobutanal + H2O2 + NH4(+)

Direction not assertedBalancedRhea 69144

spermine + O2 + H2O = spermine monoaldehyde + H2O2 + NH4(+)

Direction not assertedBalancedRhea 69148

spermine monoaldehyde = acrolein + spermidine

Direction not assertedBalancedRhea 69152

spermine dialdehyde = N-(4-aminobutyl)-3-aminopropanal + acrolein

Direction not assertedBalancedRhea 69156

agmatine + O2 + H2O = N-amidino-(2R)-hydroxypyrrolidine + H2O2 + NH4(+)

Direction not assertedBalancedRhea 69160

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