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ReactionsRhea and Human-GEM, by subsystem
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Reference

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Reach

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Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

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A reference for what the literature reports. Not medical advice.

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Index

Reactions

Reactions from Rhea and Human-GEM · Reach

reactions in the graph: 31,435

By source

Rhea18,558
Human-GEM12,877

Inferred

Reference data, not a finding. Evidence key

Filter reactions by equationSourceClear

Reactions

14,051–14,100 of 18,558 reactions from Rhea

6-methoxycoumarin + reduced [NADPH--hemoprotein reductase] + O2 = scopoletin + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Direction not assertedBalance undeterminableRhea 68564
N(5)-hydroxy-L-ornithine = (3S)-1,2-diazinane-3-carboxylate + H2O + H(+)
Direction not assertedBalancedRhea 68568
L-tyrosine(in) = L-tyrosine(out)
ReversibleBalancedTransportRhea 68572
xanthine(out) + ATP + H2O = xanthine(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 68576
L-kynurenine(out) + ATP + H2O = L-kynurenine(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 68580
L-tryptophan(out) + ATP + H2O = L-tryptophan(in) + ADP + phosphate + H(+)
Direction not assertedBalancedTransportRhea 68584

GDP-alpha-D-perosamine + (6R)-10-formyltetrahydrofolate = GDP-N-formyl-alpha-D-perosamine + (6S)-5,6,7,8-tetrahydrofolate + H(+)

Direction not assertedBalancedRhea 68588

(6S)-5,6,7,8-tetrahydrofolate(out) + ATP + H2O = (6S)-5,6,7,8-tetrahydrofolate(in) + ADP + phosphate + H(+)

Direction not assertedBalancedTransportRhea 68592

(2E,6E)-farnesyl diphosphate = beta-cadinene + diphosphate

Direction not assertedBalancedRhea 68596

(2S)-3-sulfopropanediol = 3-oxopropane-1-sulfonate + H2O

Direction not assertedBalancedRhea 68600

(2S)-3-sulfopropanediol = hydroxyacetone + sulfite + H(+)

Direction not assertedBalancedRhea 68604

isatin + NADPH + H(+) = 3-hydroxyindolin-2-one + NADP(+)

Left to rightBalancedRhea 68608

prostaglandin E1 + NADPH + H(+) = prostaglandin F1 + NADP(+)

Left to rightBalancedRhea 68612

cortisone + NADPH + H(+) = cortisol + NADP(+)

ReversibleBalancedRhea 68616

cortisone + NADPH + H(+) = 20beta-dihydrocortisone + NADP(+)

Direction not assertedBalancedRhea 68620

phycoerythrobilin-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit] = apo-L-cysteinyl(82)-[C-phycoerythrin alpha-subunit] + (2R,3E)-phycoerythrobilin

Direction not assertedBalance undeterminableRhea 68624

phycoerythrobilin-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit] = apo-L-cysteinyl(48)/L-cysteinyl(59)-[C-phycoerythrin beta-subunit] + (2R,3E)-phycoerythrobilin

Direction not assertedBalance undeterminableRhea 68628

2 reduced [2Fe-2S]-[ferredoxin] + NAD(+) + 3 H(+)(in) = 2 oxidized [2Fe-2S]-[ferredoxin] + NADH + 2 H(+)(out)

Direction not assertedBalance undeterminableTransportRhea 68632

(2E)-geranyl diphosphate = sabinene + diphosphate

Direction not assertedBalancedRhea 68636

(2E)-geranyl diphosphate = limonene + diphosphate

Direction not assertedBalancedRhea 68640

(2E)-geranyl diphosphate = alpha-thujene + diphosphate

Direction not assertedBalancedRhea 68644

2 L-cysteine = L-lanthionine + hydrogen sulfide + H(+)

Direction not assertedBalancedRhea 68648

2 L-homocysteine = L-homolanthionine + hydrogen sulfide + H(+)

Direction not assertedBalancedRhea 68652

7-oxocholesterol + NADPH + H(+) = 7beta-hydroxycholesterol + NADP(+)

Left to rightBalancedRhea 68656

17beta-estradiol 3-O-(beta-D-glucuronate) 17-sulfate + 3'-phosphoadenylyl sulfate = 17beta-estradiol 3-O-(3-sulfo-beta-D-glucuronate) 17-sulfate + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68660

17beta-estradiol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 17beta-estradiol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68664

16alpha,17beta-estriol 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 16alpha,17beta-estriol 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68668

16alpha,17beta-estriol 16-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 16alpha,17beta-estriol 16-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68672

estrone 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = estrone 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68676

3alpha,20alpha-dihydroxy-5beta-pregnane 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 3alpha,20alpha-dihydroxy-5beta-pregnane 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68680

testosterone 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = testosterone 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68684

3beta-androst-5-en-17-one 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 3beta-androst-5-en-17-one 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68688

3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 3alpha,17alpha-dihydroxy-5beta-androstane-11-one-17beta-carboxylate 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68692

17beta-estradiol 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 17beta-estradiol 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68696

16alpha,17beta-estriol 17-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 16alpha,17beta-estriol 17-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68700

3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate) + 3'-phosphoadenylyl sulfate = 3alpha-hydroxyetiocholan-17-one 3-O-(3-sulfo-beta-D-glucuronate) + adenosine 3',5'-bisphosphate + H(+)

Left to rightBalancedRhea 68704

(2E)-geranyl diphosphate + H2O = linalool + diphosphate

Direction not assertedBalancedRhea 68708

(2E,6E)-farnesyl diphosphate = (1S,2S,4R)-beta-elemene + diphosphate

Direction not assertedBalancedRhea 68712

(2E,6E)-farnesyl diphosphate = germacrene D + diphosphate

Direction not assertedBalancedRhea 68716

lanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 26-hydroxylanosterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 68720

26-hydroxylanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 26-oxolanosterol + oxidized [NADPH--hemoprotein reductase] + 2 H2O + H(+)

Direction not assertedBalance undeterminableRhea 68724

26-oxolanosterol + reduced [NADPH--hemoprotein reductase] + O2 = 3beta-hydroxy-lanosta-8, 24-dien-26-oate + oxidized [NADPH--hemoprotein reductase] + H2O + 2 H(+)

Direction not assertedBalance undeterminableRhea 68728

ganoderate DM + reduced [NADPH--hemoprotein reductase] + O2 = hainanate A + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 68732

ganoderate TR + reduced [NADPH--hemoprotein reductase] + O2 = ganoderate Jc + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)

Direction not assertedBalance undeterminableRhea 68736

7-oxocholesterol + NADPH + H(+) = 7alpha-hydroxycholesterol + NADP(+)

Direction not assertedBalancedRhea 68740

2 (R)-3-phenyllactate + 2 (R)-lactate + 4 L-leucine + 4 S-adenosyl-L-methionine + 8 ATP = PF1022A + 8 AMP + 4 S-adenosyl-L-homocysteine + 8 diphosphate + 8 H(+)

Direction not assertedBalancedRhea 68744

O-phospho-L-seryl-[protein] + alpha-D-glucose 1-phosphate = alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein]

Direction not assertedBalance undeterminableRhea 68748

alpha-D-glucose 1,6-bisphosphate + L-seryl-[protein] = O-phospho-L-seryl-[protein] + alpha-D-glucose 6-phosphate

Direction not assertedBalance undeterminableRhea 68752

4 (R)-3-phenyllactate + 4 L-leucine + 4 S-adenosyl-L-methionine + 8 ATP = PF1022B + 8 AMP + 4 S-adenosyl-L-homocysteine + 8 diphosphate + 8 H(+)

Direction not assertedBalancedRhea 68756

3 (R)-3-phenyllactate + (R)-lactate + 4 L-leucine + 4 S-adenosyl-L-methionine + 8 ATP = PF1022C + 8 AMP + 4 S-adenosyl-L-homocysteine + 8 diphosphate + 8 H(+)

Direction not assertedBalancedRhea 68760

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